Very proud of my student @VinsonChan who has performed a systematic review on COVID-19 and Urology. I think it does contain important information that every urologist should know. It was just published at @wjurol, and you can find the paper here :) link.springer.com/article/10.100… (1/n) 
We conducted a literature search up to 8th April, and 25 studies were included in the quantitative synthesis. We summarized the data regarding urinary symptoms, acute kidney injury, viral RNA in urine and stool specimens, and clinical outcomes of renal transplant patients. (2/n)
We found 21 studies including 3714 patients, and none of them had urinary symptoms because of COVID-19. Two patients had urinary symptoms (because of underlying urological problems) PLUS fever, which eventually turned out to be COVID-19. (3/n)
Acute kidney injury is not uncommon. We found 12 studies with 3266 patients, and the pooled rate of AKI is 7.6%. ACE2 is a major receptor for viral entry to human cells, and kidney has abundant ACE2 expression. This raises the possibility of a direct injury from COVID-19. (4/n)
In patients who developed AKI secondary to COVID-19, the prognosis is very bad. In our review, we were able to retrieve data from 65 patients, and the pooled mortality rate is 93.3% - Very very high. (5/n)
11 studies reported data regarding viral RNA detection in urine. There were 11 studies with 195 patients, and the pooled rate of RNA positivity was 5.7%. The duration of viral shedding is however unclear. Whether this represents a genuine infective risk is also unknown. (6/n)
11 studies reported data regarding viral RNA detection in stool. There were 12 studies with 325 patients, and the pooled rate of RNA positivity was 65.8%. RNA was detected as early as 2 days from symptom onset, and could be persistent up to 47 days from symptom onset. (7/n)
There were 19 reported cases of COVID-19 in renal transplant patients. 31.6% required non-invasive ventilation, and the mortality rate was 15.4%. COVID-19 seems to have a more severe clinical manifestation in renal transplant patients. (8/n)
I hope this paper is able to compile some basic BUT important information for health care professionals in urology. Please take care and stay safe – I am sure we can win over this pandemic! (9/9)
