When the first white settlers arrived in Montana, the native Salish people warned them to not settle the West side of the Bitterroot River.
Ignoring these warnings, a small group of people colonized that side of the river.
Three quarters-75%-died of a mysterious disease.
The Bitterroot river carves out a 75 mile canyon in Western Montana.
It's not deep at all, averaging only about 3 feet. Animals and humans cross it very easily, and it's not really a barrier to any kind of travel.
The Salish believed evil spirits lived in the area.
Saint Mary's mission, founded in 1841, was the first permanent European settlement in Montana.
The European settlers weren't very nice to the natives, and the poor relationship caused the mission to close.
A trading post which mostly serviced trappers, Fort Owen, popped up about 10 years later.
When the owner, John Owen discovered gold in the area, this set off a gold rush in the area.
Unfortunately, the disease on the West side of the bitterroot river made life difficult.
Not much was known about this disease until the early 1800s, when the state board of health brought in Louis Wilson and William Chowning to investigate.
They did a lot of research on the disease, eventually creating the map below
At the same time, a few other doctors were sent to investigate along with Williams and Chowning.
Together they found out:
It was caught in springtime
It was caught outdoors
The Salish rarely got the disease
The more these early researchers found out about it, the more mysterious it became.
People became really sore, and developed a fever. A rash of purple spots dotted the body. Some would go blind or deaf. Loss of balance was pretty common.
It didn't appear to be contagious.
The disease remained mysterious, until two doctors L.P. Macalla and H.A. Bereton had a patient who was bitten by a tick.
One which looked a lot like the one below.
That patient later developed the symptoms described in the post above.
So they took the tick, and allowed it to bite another healthy person.
They got the disease.
So they fed a tick on that person, and THAT person got the disease as well.
Unfortunately, they didn't publish these results until much later.
At the same time as this was going on, a young microbiologist by the name of Howard Taylor Ricketts set up shop in the area.
With few laboratory supplies-all of his experiments were done in a tent-he began to look for the cause of this perplexing disease.
It didn't take too long before he met a local family living in black measles territory. Their son, William, 10 years old, had caught the disease.
When Ricketts came to visit he found...ticks.
Lots of ticks. Everyone in the family had been bitten by them.
So he drew blood from William Langdon, stained it with a chemical called Eosin, and found bacteria.
He dissected ticks in the area, found the bacteria.
He also found that he could pass the disease among guinea pigs.
He named this bacteria after himself, Rickettsia rickettsii.
The disease would go on to be well studied, and go by a few other names. However, over time, the scientific community settled on a name originally published in 1903.
Rocky Mountian Spotted Fever
The story of this disease is one I've wanted to tell for awhile, and by no means does it end here.
The story of RMSF is a really important cautionary tale for why people like us, those who specialize in outreach, are so important.
In addition, the Bitterroot strain of RMSF has remained a biological mystery that has baffled scientists to this day.
So, next week, I'll be talking about part 2:
The legal war over Rocky Mountian Spotted Fever
Also, on our Deep Dives, we're absolutely terrible at acknowledging our sources and we need to work on this.
Here are the sources we consulted if you want to read more:
So, I've been thinking about how to properly respond to this...and there's really no way to do that because we will never be able to take our ecosystems from Earth to other planets.
What Musk proposes here is (as @Myrmecos pointed out) simply impossible.
The most important is a reference strain. Lots of mosquitoes were being bred in labs before pesticides were introduced, so we *know* they're not resistant to them.
If we're curious about a modern population, we can compare and use them as a standard.
Besides reference strains for pesticides, we know that the lab reference strains can transmit most of the 'normal' diseases that Ae. aegypti spread.
However, not all populations of Ae. aegypti spread every disease.