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It's time for another quick update on paediatric #COVID19 evidence!

Most new information is about transmission so we'll focus on that for now. It's pretty interesting!

Lets take a look...

#FOAMed #tweetorial

First, pre-print systematic review of transmission (search on May 16th)…

I won't go into depth as all studies covered in a previous thread, however useful meta-analysis of contact tracing studies

OR = 0.44 of infection in children compared to adults

This is conservative as they use raw Odds Ratios, not those adjusted for contact type from initial studies

Some criticisms of these include potential lack of testing of non-symptomatic children missing cases

Well fortunately we've got some new evidence there...

Here are 2 studies which both tested all household contacts regardless of symptoms


New York…

Both found children half as likely to become infected as adults

How about false negatives as difficult to swab kids?

Well in the Netherlands they didn't rely on swabs. They did serology.…

Guess what? Same thing!

Young children about 50% as likely to get infected as adults/teens in household

Same study looked at infection pairs from a national database to see who was infecting who.

Almost all transmission adult to adult. Minimal child to adult or child to child.

Finally a revisit to a sero-prevalence study from Switzerland (prev seen as pre-print)

Population tested in Geneva and results adjusted and extrapolated for population estimates…

Children <10yrs had Odds of 0.32 for being infected compared to adults

Studies are consistently finding children get infected less easily than adults (however you look for it) and good size sero-epidemiology finding lower numbers of younger children have been infected

Super spreaders? Doesn't look like it.

For all this and more on paediatric #COVID19 evidence, check out our review (in collaboration with the RCPCH) of ALL the published evidence so far on @DFTBubbles

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