Thread by @Ryan_Mac_Phd

Very proud to have been a part of this team effort here at @UNC.

High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States
biorxiv.org/content/10.110…

We show that the D614G mutant in the Spike protein of SARS-CoV-2 is becoming increasingly prevalent in symptomatic cases in North Carolina. We also show that community transmission is the primary driver of virus spread in the Tar Heel state.

This was done through deep-sequencing of 175+ SARS-CoV-2 positive samples. Our deep-sequencing approach was sensitive and accurate, complementing current testing protocols.

I want to emphasize that this work is in the pre-print stage and going through the peer-review process. We look forward to reviewers making this work better through critical and careful evaluation for final publication. This step in the scientific process is pivotal.

So much hard work by so many went into this, namely @LabDittmer, @DamaniaLab, @melmillerphd, @cmthompson15, @Easonred57, @DanielleChapp14, @Baric_Lab, & many others.
A lot of great work on SARS-CoV-2 is happening at @UNC, and I'm humbled to be a part of it.
#GoHeels

Can't believe I forgot to tag @langept. We spent many hours processing samples while our faceshields fogged up.