Are some people naturally vaccinated for Covid-19?
Our new study found a cross-immune response between Covid-19 and seasonal coronaviruses that only cause common cold:
Covid-19 exposed have antibodies to both Covid-19 and seasonal coronaviruses
Our new study found a cross-immune response between Covid-19 and seasonal coronaviruses that only cause common cold:
Covid-19 exposed have antibodies to both Covid-19 and seasonal coronaviruses
Unexposed individuals have antibodies to seasonal coronaviruses similar to found in exposed individuals
A small fraction of unexposed had Covid-19 antibodies but a larger sample is needed and the function of this is unclear
We searched for seasonal coronaviruses more abundant in unexposed, as this would indicate protection, but we did not find such antibodies
We searched for seasonal coronaviruses more abundant in unexposed, as this would indicate protection, but we did not find such antibodies
Almost all exposed individuals developed antibodies to SARS-Cov-2, allowing us to develop an accurate serology test using our tech
But the virus regions to which exposed people had antibodies differed between people. This may have implications for some vaccines being developed
But the virus regions to which exposed people had antibodies differed between people. This may have implications for some vaccines being developed
Bottom line, we did not find evidence for natural vaccination and protection from Covid-19 in unexposed people, but with appropriate samples from people who had different disease severity our tech can help resolve this critical question
The full research is here:
medrxiv.org/content/10.110…
The work has not been peer reviewed yet
Great work led by Shelley Klompus, Sigal Leviatan, Thomas Vogl, @KalkaIris, @Nastya08434121, and @AdinaBlueBird
medrxiv.org/content/10.110…
The work has not been peer reviewed yet
Great work led by Shelley Klompus, Sigal Leviatan, Thomas Vogl, @KalkaIris, @Nastya08434121, and @AdinaBlueBird
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