Some good news: There are signs #Covid19 is getting less deadly for hospitalized patients as doctors gain experience and a handful of new drugs have come online bloomberg.com/news/articles/…
This is, to be clear, about *individual* risk. How many people get seriously ill or die at the country will still depend largely on the rate of spread. For that to go down, it's public health measures and a vaccine. bloomberg.com/news/articles/…
That's because, as @FayCortez wrote here, it's very, very, very difficult to come up with *cures* for viruses. The best bets are supportive care, etc: bloomberg.com/news/articles/…
“We have better and more rapid access to diagnosis. We have more knowledge about what drugs to use and what drugs not to use. We have more experimental treatments available. All of those contribute to possible improvements in the mortality rate.” bloomberg.com/news/articles/…
Good reporting here from @LivRaiReports about the changing aspects of Covid care, which will have major implications for a fall surge.
The data on what's happening here aren't great. There's lots of look at per capita deaths, excess deaths, etc. Some of the better work involves risk-adjusted looks at hospital admits (which still has limitations).
Astudy of a NYC hospital system's #Covid19 hospitalizations in March-->June (n=4,689). In the first half of March, mortality rate for hospitalizations was 23%. By June, it was down to 8%. (Adjusted for factors like age, race, obesity + underlying illness) bloomberg.com/news/articles/…
None of this means #Covid19 still isn't dangerous: “This does not mean that coronavirus is now a non-dangerous disease. It remains a very serious threat to public health.”
Docs outside of NY also learned from what happened here. Those places that are now getting hit have better knowledge: “We kind of had a play book before we even started seeing any patients in Texas.... We understand the things that work at this point with Covid much better.”
These gains are marginal, but they matter: “Even if these things aren’t cures, they help a small percentage do better.... You add several of those things up and you’ve got a better outcome overall.” bloomberg.com/news/articles/…
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These are astonishing results in weight loss. 24.% weight loss at 48 weeks. Average loss of 58 pounds. Blows out of the water everything else we've seen so far.
For context: Every other weight loss drug we've seen is around 15%. Which was already awesome. This is 10pp higher than that.
The debate has been around "will the new pill versions wipe out the injections" and this just reset the conversation.
This drug is still in mid-stage testing. A lot could happen between now and then. And the market for these products will likely fragment based on how they're administered, how strong they are and the side effect profiles.
Over the last several months, I spoke to dozens of disease modelers, epidemiologists and public health officials about what's changed, what they don't know, what they wish they knew, and how they think about what we've been through. bloomberg.com/news/articles/…
Our data on Covid-19 hospitalizations is too blunt. We lump in people hospitalized "with" Covid and people hospitalized "for" Covid. This is a complicated, fraught topic, but an important one.
Reporting in Kentucky hospitals, I saw a lot of covid patients. What are they like?
One man was in a high-flow oxygen mask. He was lying in bed, making tiny, fast bites at the air, gasping.
He looked like he was suffocating, like a dying fish washed up on the beach.
I saw other patients on ventilators. They're pale and sedated.
They look dead, until the ventilator pushes air into their lungs and their chest heaves upward. None of the looks natural, and it's very, very upsetting to watch.
I also saw patients on ECMO (heart-lung bypass). It can be a life-saving bridge to a lung transplant or recovery. About half of the patients die.
It is also not gentle -- the patients have a garden hose-sized tube in the jugular and another in the groin. Plus a half-dozen IVs.