1/ Has the UK ended up with the worst possible #SARSCoV2#COVID19 combination?
- /Everyone/ is upset & confused
- Personal life greatly restricted
- Trust in strategy at a low
- Still possibly not applying restrictions consistently enough to make a decisive difference
2/ The local-lockdown strategy seems to have contained outbreaks over the summer - I was encouraged by this.
Convinced that was the end of it, however, the govt seems to have turned attention totally to businesses instead of the possibility that a 2nd wave could come in autumn.
3/ I do not believe a strict lockdown, as in spring, is necessary to stop #SARSCoV2. But the idea that people can totally isolate themselves in personal life, yet continue to patronise bars & restaurants & go work in offices like normal - & this stops transmission - is farcical.
4/ And, though economically less ideal, I believe strict personal restrictions are harder for the public to bear than limitations on how pubs & restaurants operate. Personal restrictions are invasive, isolating, & confining - and punch hard at mental wellness.
5/ We can save businesses (if we so wish) with financial schemes - but it's not so easy to keep the public healthy, happy, & continuing to make good decisions to minimise transmissions by following guidelines.
Of course, some personal restrictions are likely needed.
6/ But these should be carefully made, to accommodate families, children, & differences in types & places of meeting (meeting outdoors & keeping distance is likely quite safe). Other higher risk settings should be regulated to minimise need for personal restrictions when possible
7/ Communication & public perception *matter* when you're trying to get an entire country on-side to give things up for a greater goal!
When messages are confusing & restrictions seem contradictory or unfair, you lose engagement & trust and deplete willpower.
8/ Statements like this (presumably trying to save the govt face): "Testing & tracing has very little or nothing to do with the spread or the transmission of the disease"
Scramble messages about what's important. (Why get tested if it doesn't matter?)
9/ The first step to fixing a problem is admitting you have one - something the UK govt seems loath to do with regard to Test & Trace.
My heart aches to see the UK in the position it's in right now. It didn't need to be this way... & doesn't need to continue this way.
10/ It's not going to be easy to turn things around now, but I believe it's possible. However, it will take investment, planning, balanced restrictions - and much, much better communication.
A lot of work needs to be done to get the public back on-board. I hope it starts soon.
11/ The takeaway here is balance. #SARSCoV2 transmission likely isn't just happening at home /or/ at businesses/pubs/etc, but both. We need strategies that minimise risk in both settings, while allowing both to proceed as normally as is possible, based on case-trajectories.
12/ And clear, effective, balanced guidelines aid good communication & build back trust. 'Fair' restrictions that are 'worth it' are easier for people to tolerate. We may have multiple 'upswings' this winter that require action - we need the public to buy-in /every time/.
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I'm excited to announce a new paper with @MLReichmuth and @C_Althaus, out now in @PLOSPathogens!
We used phylogenetics & modelling to investigate the introduction & expansion of #SARSCoV2 Alpha & Delta variants into #Switzerland & to simulate different interventions.
1/17
First, we wanted to estimate the number of times Alpha & Delta were introduced into Switzerland before they were dominant.
For this we used sequences: we looked for where Swiss Alpha/Delta seqs descend from non-Swiss sequences - coming to Switzerland from elsewhere.
2/17
We looked at two ways of counting these introductions:
Liberal: every Swiss sequence coming from non-Swiss sequences is an introduction
Conservative: only the first Swiss sequence in a subtree of mixed-Swiss-non-Swiss sequences is an introduction
Benevolent dictators have no place in academic science.
I don't care if they usually make the right decision. Or if people don't think they've abused their power yet.
Science should not depend on one person being well-behaved.
Balance should be built in, power distributed.
1/5
"If you want to go fast, go alone, if you want to go far, go together" the African proverb says.
Can driven, visionary people start up groundbreaking ideas & cut through barriers to implement them? Absolutely! This 100% is part of science.
2/5
But if you want your idea to be a keystone of science communities & the public, you have to make it about more than *you*.
If you want to run a private business, go do that.
If you want to be keystone of public science, you have to be transparent, trustworthy, & stable.
3/5
23B (XBB.1.16) is now available on CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.
As I covered earlier, 23B (XBB.1.16) is descended from the recombinant 22F (XBB) variant, with some additional mutations. You can read more about how it evolved & acquired those mutations below 👇🏻.
Also from this article:
'Marion Koopmans ... says she has received multiple calls from Bogner“with a rather intimidating tone.” So have colleagues, she adds. “I have heard similar experiences from quite a few.”'
And:
"And Science heard many stories about researchers who saw their data curtailed, or cut off, without explanation. Some linked the actions to their being critical of GISAID or being seen as a potential threat."
If you're an early career researcher (yes even 'just' a PhD student!) 1 of my biggest pieces of advice would be:
Go claim/create your Google Scholar page!! 👈🏻✍️🏻
I put this off bc I thought I 'didn't have enough on it'. I also generally thought "nobody is looking for me".
1/4
Now that I'm (a little) on the other end, I see how wrong I was.
It's *just fine* to not have "much" in your Google Scholar profile - anyone worth their salt will be evaluating you relative to your career state.
Much more important: to be findable!
2/4
And alongside that: it's so useful to have an easy way for people to see what your field is & what you've been up to/who you work with/your expertise.
Google Scholar is also pretty easy to maintain (will vary depending on how unique your name is), as it auto-updates.
3/4
23A (XBB.1.5) is now available on CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.
As I covered earlier, 23A (XBB.1.5) is descended from the recombinant 22F (XBB) variant, with some additional mutations. You can read more about how it evolved & acquired those mutations below 👇🏻.