Thread by @DrEricDing

WORRIED—you almost **never ever** give someone a clinically untested drug like @Regeneron’s polyclonal antibody drug—unless it’s for compassionate use for someone severely ill, or you’re crazy. Right @VincentRK? This smacks of utter craziness or desperation. #COVID19 #TrumpCovid

https://twitter.com/maggienyt/status/1312124050638995456

2) the 8 gram @Regeneron dose is also supposedly the *higher* dose according to Sanjay Gupta on CNN.

3) more odd. The 8 gram dose isn’t even more effective than the lower dose. It’s already a somewhat unproven drug other than for viral dose. Why did they say even try it not to mention. Why the higher dose. These are weird signals.

https://twitter.com/sciencecohen/status/1312131983837806593

4) Furthermore, the existing clinical trial showing @Regeneron’s latest polyclonal antibody shows.... *NO EFFECT* on clinical outcomes.

HT to @andreafeigl1 for finding this.

investor.regeneron.com/static-files/a…

5) Also notice the big pharma lie/spin in their slide title — they say “numerically lower” — yet the P value indicates no significant effects (P>0.05). Not even close! This is why you never take pharma industry presentations at face value.

6) Sidenote: “medical visits" also included telemedicine, urgent care, or ER. So not all hospitalizations. And what about overall population? Nope again. Also notice how few ER, and Urgent care visits there are: tiny single digits. This is not a proven drug! Crazy WH using it.

7) Correction: my better half Dr @andreafeigl1 nudged me at 530am to point out the @Regeneron REGN-COV2 antibody cocktail is technically a “multi monoclonal” antibody cocktail instead of WH’s errant false claim it is “polyclonal” in the physician letter. So I stand corrected.