Schools and personally-acceptable risk (THREAD)

This thread is an attempt to address questions certain UK parents and school staff have raised to me.

I’m not an epidemiologist, but as a mathematician I’m weighing in on certain general notions of probability and risk. 1/12
No one knows how bad this 2nd wave will get. It depends on what hard and soft measures are implemented and when, and how they are supported.

But I think it is ethically and scientifically unjustified to trivialise the concerns of parents and school staff about school risk. 2/12
Yes, there’s now good evidence that the covid mortality rate for healthy under-19-year-olds is likely no worse than flu *for*that*demographic.*

But that is only one type of risk. 3/12
There’s the risk of transmission to higher-mortality-rate school staff members.

There’s the risk of transmission to higher-mortality-rate family or household members of staff or students. 4/12
There’s the risk that a staff or household member (or concevably even an adolescent) will suffer long-term lung or heart damage, or acquire “long-covid.”

Many such non-fatal risks are still poorly understood and poorly quantified. 5/12
There’s the risk of feeling responsible for participating in an otherwise avoidable transmission chain that ends up leading to increased covid spread,

adding not only to direct covid deaths, but also to burdens on the health system that harm non covid patients. 6/12
In the absence of any remote-school infrastructure or support, there’s the risk of repeated disruption to education when outbreaks send “bubbles” home to self-isolate.

There’s similar risk of education disruption during self-isolation due to symptomatic household members. 7/12
** No one can dictate to a person how much a particular risk ought to mean to them. **

Researchers can try to estimate the *probabilities* of events,

but even with known probability, the actual negative *cost* you associate to a particular risk is a very personal choice. 8/12
Of course, on the other hand, there are *also* risks to job-insecure or otherwise-vulnerable families forced into remote schooling.

But this doesn’t have to be an all-or-nothing thing. 9/12
The US school district where I’m currently on sabbatical is creating remote schools out of students and school staff who don’t want to attend school in person.

In fact, many US school districts are doing this, and I don’t see why this can’t happen in the UK. 10/12
There’s enough demand for remote school here that a substantial fraction of the school population is participating in these new remote schools,

which means that the remaining school population has much more space to spread out and socially distance in physical schools. 11/12
School staff, students, and parents deserve to have government and local authorities to treat these concerns with respect.

And all sides could potentially benefit from flexible solutions that attempt to serve both remote-school and in-person school needs and preferences. 12/12
⬇️ Cued to an excellent question by a clinically vulnerable parent:

“I’d like the choice to temporarily educate my child at home. ..I can’t shield from my child if she goes to school, because I think that would affect the mental health of both of us.”

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More from @SarahDRasmussen

3 Oct
@SmutClyde @michaelroston @ThePlanetaryGuy Unfortunately, neither my World Scientific institutional access through U Cambridge nor that through IAS Princeton includes IJGMMP—I guess limited demand.

But there’s a retracted Mac J Med Sci pub by the same authors (et al) w/ “topoisomerase-like waves.”
researchgate.net/profile/Uwe_Wo…
@SmutClyde @michaelroston @ThePlanetaryGuy The retracted article’s argument seems to go:

1) topoisomerase unwinds DNA,
2) um, waves can be kind of wound up looking (?),
3) ergo, waves could unwind DNA like topoisomerase.

Thing is, that doesn’t make sense topologically.
(And I’m a topologist for my day job.)
@SmutClyde @michaelroston @ThePlanetaryGuy Topoisomerase doesn’t unwind DNA like a ball of yarn; it untangles by *crossing*changes*—temporarily snipping DNA for it to pass through itself, thereby changing the embedded topology of the DNA as a tangle/knot.

Simply “pushing DNA around” with a wave would NOT change topology.
Read 9 tweets
27 Sep
@ingridjohanna66 @threadreaderapp Thanks!

Initially stumbled on all this by accident.

I’m new to Twitter. Have mostly tried the academic route on this. The letter of corr + systematic review I sent to LC&AH on this were rejected, and now my univ’s Research Gov Office is working with UKRIO to organise an audit.
@ingridjohanna66 @threadreaderapp I originally worked alone on this, since didn’t want to disrupt med researchers at a time like this.

I know journals are doing the best they can with an avalanche of submitted articles that could influence policy that saves/jeopardises lives.

Difficult to know how hard to push.
@ingridjohanna66 @threadreaderapp (To clarify, what I sent was rejected by the LC&AH editor without ever being sent to peer review.)
Read 4 tweets
25 Sep
School closures + bad science (THREAD)

Remember that 6 Apr Lancet C&AH systematic review on school closures--with that media-amplified "2-4%" statistic--by a UCL team led by RCPCH president + SAGE member Russell Viner?

It has some serious problems. 1/
thelancet.com/journals/lanch…
Why does this still matter?

1. Viner's Review continues to be cited. A lot.

2. School closure was a first-aid response. Transitioning to long-term solutions calls for reexamining the science.

3. Serious enough cases of bad science raise concerns about the source. 2/
My first alarm bell?

The Review Summary's claim that "school closures alone would prevent only 2-4% of deaths" is a badly mis-contextualised statistic from

--wait for it--

the very Imperial College study [31] that prompted UK govt to close schools. 3/
imperial.ac.uk/media/imperial…
Read 23 tweets
27 Aug
THREAD. 1/
Pure mathematician here. Great questions.

It's literally my job description to create mathematics that has no known real-world use.

It's true that algebra had applications even millennia ago. But that is *not* what motivated Pythagoras.
2/ Pure mathematicians develop math according to what’s beautiful or surprising, or connective between diff areas of math.

It's partly done as an act of human achievement and creation, and partly done knowing that real-world uses might be found yrs, decades, or centuries later.
3/ Classical math education was less about learning rote skills and more about learning to think creatively, logically, and critically.

For example with Euclid's geometry, "Sure these lines look parallel, but what assumptions are we making here? How do we know for sure?"
Read 4 tweets
25 Aug
@Dr2NisreenAlwan I’m personally involved in an ongoing audit of Viner’s April Lancet C&AH school closures Review.

It was basically a sham study, with objective instances of intentionally altering what articles said. None of the articles they cited can legitimately be used to support their point.
@Dr2NisreenAlwan Can send documentation to anyone interested. My university’s Research Office is working on moving things forward, but journals are amazingly resistant to engaging with post-pub discovery of problems, no matter how extreme.
@Dr2NisreenAlwan To give just 1 examp, for 2 articles the only data they used was failure of a Singapore school temperature screening programme to find SARS cases. The programme started 30 Apr 2003.

Failed to mention: The last 3 ever Singapore cases from the 2003 epi were on 25, 27 Apr, + 5 May.
Read 4 tweets

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