Dr. Fauci takes a moment to recognize our own sacrifice in this pandemic. Thank you for your work in this pandemic! #CHEST2020 2/
Dr. Fauci will talk about COVID-19: Public Health and Scientific Challenges #CHEST2020 3/
This is not the first severe human Coronavirus disease we've faced. #CHEST2020 4/
COVID-19 is the disease, but the virus that causes it is SARS-CoV-2! #CHEST2020 5/
With over a million deaths and 37.9 million cases, we haven't seen a pandemic of this size in over 100 years! #CHEST2020 6/
The US is the worst hit nation in the world! #CHEST2020 7/
The US is different then the EU because we didn't do what is necessary to slow the spread of the virus. #CHEST2020 8/
You can see from these graphs that the US did not shut down our mobility the way other countries did. #CHEST2020 9/
The virus is mainly transmitted through respiratory droplets, but there is some aerosol transmission and transmission through fomites. Note that animals are not a major source of infection, so this is not an excuse to drop your pet off at the pound!!! #CHEST2020 10/
The risk of transmission depends on where you are and the activities done there. #CHEST2020 11/
40-45% of cases are asymptomatic and these people are spreading the virus! This is why it's not enough to just stay home if you feel ill! #CHEST2020 12/
Fundamentals to prevent acquiring and transmitting SARS-CoV-2 #CHEST2020 13/
There is a varied clinical presentation including the loss of smell/taste. #CHEST2020 14/
A case fatality rate of 2.3% is HUGE! THIS IS NOT THE SEASONAL FLU! #CHEST2020 15/
Manifestations of severe COVID-19 disease #CHEST2020 16/
Even those people who do recover can still have persistent symptoms! #CHEST2020 17/
The people most at risk for severe COVID-19 illness include older adults and those with underlying medical conditions. #CHEST2020 18/
You can see here the risk of hospitalizations by age. #CHEST2020 19/
These are underlying medical conditions associated with an increased risk of severe COVID-19 illness. #CHEST2020 20/
These are underlying medical conditions that MAY confer an increased risk. Not that just being overweight is on this list. That's a HUGE portion of the US population! #CHEST2020 21/
There has been very concerning racial/ethnic disparities with COVID-19, with much higher hospitalization rates in Hispanic and black patients. #CHEST2020 22/
An expert US panel has been developing the NIH treatment guidelines for COVID-19. #CHEST2020 23/
Currently recommended treatments include Remdesivir and Dexamethasone. There are a number of other therapies under investigation, too. #CHEST2020 24/
The use of Dexamethasone in hospitalized patients with COVID-19 was associated with a 36% reduced mortality in ventilated patients and an 18% reduction in patients on supplemental oxygen! #CHEST2020 25/
There are a number of studies ongoing on the use of monoclonal antibodies. #CHEST2020 26/
The efforts to make a COVID-19 vaccine are unprecedented and there are a number of vaccine candidates currently in phase 3 trials. #CHEST2020 27/
If you want further information on the ongoing clinical trials check out this website! #CHEST2020 28/
Thank you to Dr. Fauci for a fantastic and informative keynote session!!! #CHEST2020

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More from @gretchemaben

19 Oct
My last tweet-ucation session of day is “Circadian Rhythms for the Chest Clinician: It’s About Time”! #CHEST2020
Our first session is "Circadian Rhythms: Mechanisms and Role in Health and Disease” with Dr. Phyllis Zee! #CHEST2020 Image
One of the most prominent changes in our physical environment is the rotation of the Earth, and our body has to adjust to that. Our BP, platelets, temperature, alertness, and more vary at different times of the day. #CHEST2020 Image
Read 56 tweets
19 Oct
Here’s my tweet-ucation from the “Updates on Diffuse and Orphan Lung Diseases” session!
The next session is "Incidence, Mortality, and Characteristics of Patients Admitted with Pulmonary Alveolar Proteinosis in the US" with Rodrigo Garcia-Tome #CHEST2020 Image
PAP is a rare disease. PAP has a variable clinical course, sometimes with spontaneous resolution but other times with progressive respiratory insufficiency. #CHEST2020 Image
Read 47 tweets
19 Oct
We sometimes also under-treat patients due to racial and socioeconomic biases (THIS IS NOT OKAY!!!) #CHEST2020 Image
Key Takeaways! #CHEST2020 Image
The next session is "Anxiety and Agitation in the ICU: How to Treat It" with Dr. Katie Pendleton (@PendlKM)! #CHEST2020 Image
Read 18 tweets
19 Oct
I can’t go to the whole session (have to leave early to moderate another), but get ready for some tweet-ucation coming your way on “Preventing and Managing Pain, Agitation, and Delirium in the ICU! #CHEST2020
The first session is "" with Dr. Kusum Matthews! #CHEST2020 Image
Let's start with a clinical case of Patient MR. #CHEST2020 Image
Read 18 tweets
19 Oct
First up for today’s #CHEST2020 Tweetucation is “Asthma: Mechanisms and Management” which I am co-moderating with the one and only Dr. Andrew Berman (@Pulmonary_O2)!
The first presentation is on "IL-13 augments histone demethylase JMJD2B/KDM4B expression levels, activity and nuclear translocation in airway fibroblasts in asthma." with Khuloud Bajbouj (@KBajbouj)! #CHEST2020 Image
This study aimed to explore IL-13's role in airway tissue remodeling and fibrosis in severe asthma. #CHEST2020 Image
Read 39 tweets
18 Oct
Next item for Tweet-ucation is "Masterly Inactivity: The Art and Science of Reducing Unnecessary Interventions in the ICU"
First up we have @karanskahlon talking on: "ABG and Arterial Lines for All: A Flawed Paradigm?" #CHEST2020
Do we really need ABGs? Why do we get them? #CHEST2020 Image
Read 43 tweets

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