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Peter English #FBPE Profile picture
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27 Nov, 4 tweets, 1 min read
Editor of @bmj_latest @KamranAbbasi on PHE:

"PHE is no more after 7 years of controversy.

bmj.com/content/371/bm…
1/4
"…Its proximity to government and industry, together with funding cuts to local authorities, essentially set it up to fail and now to become the government’s fall guy for a flawed pandemic response…
2/4
"…PHE is being replaced by a national institute for health protection, which may well be closer still to government and industry…
3/4
"When accountable national organisations move in the direction of political and commercial interests, public trust is eroded, and the power of unaccountable and self-serving social media platforms only grows."
4/4

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More from @petermbenglish

Peter English #FBPE Profile picture
30 Nov
Hi @ajpollard1 @OxfordVacGroup !

What does "ChAdOx1 vector is modified to be replication deficient" mean?

Can it induce production of antigen proteins if it doesn't replicate at all?

Does the lack of replication reduce the immune response to the vector?
1/3
Are ChAdOx1 vector vaccines contraindicated where live virus vaccines are contraindicated (and why [not]?)

Where can we find a New Scientist level explanation of these things?
2/3
If it is "replication deficient", how do you produce it? Can you culture it?

Parenthetic thought:
Are viruses ever "live", and where does this vector vaccine fit? Is it a Schrödinger's virus, alive or dead, depending on your reason for asking?
3/3
Read 4 tweets
Peter English #FBPE Profile picture
27 Nov
Editor of @bmj_latest @KamranAbbasi on Facebook (& the Danish mask study):

"A disagreement among experts, especially about interpretation of a study, is a common occurrence. It is the usual business of science. Only, Facebook didn’t see it that way…
bmj.com/content/371/bm…
1/7
"The social media platform that allows statements about injecting bleach to prevent covid-19, [and] calls to behead the leading US expert on pandemics, decreed… Heneghan & Jefferson should be censured for misinformation after they reposted their Spectator article on [FB]…
2/7
"It is possible to disagree with Heneghan and Jefferson about the robustness and interpretation of the DANMASK-19 trial—which I do—and still believe it is wrong that their opinion of it was marked as “false information.”…
3/7
Read 7 tweets
Peter English #FBPE Profile picture
27 Nov
CCGs to be replaced as commissioners by ICSs, under NHS England proposals pulsetoday.co.uk/news/nhs-struc…
@jkaffash @costanza_fierce
The wheel continues to rotate…
1/8
They keep creating bodies in which trusted GPs are the commissioners; and they keep ensuring that they fail and revert to being something like a 1980s Health Authority...

I wrote about this in BMJ 10 years ago. bmj.com/content/340/bm…

2/8
"Politicians realise that people trust their general practitioners more than politicians or faceless commissioners in the health authority, primary care trust, or whatever the organisation is called at the time…
3/8
Read 9 tweets
Peter English #FBPE Profile picture
15 Nov
I despair. Look at nhs.uk/conditions/cor…

"You may want to tell people you've been in close contact with in the past 48 hours that you might have coronavirus."

You absolutely MUST do so, immediately…
1/
"[Your contacts] do not need to self-isolate unless they're contacted by the NHS Test and Trace service".

Which will only happen after they've infected most of the people they could've; and too late to have much effect.
2/
We will never get on top of this pandemic like this. To work, TTIS (test, trace, isolate, support) will never work unless contacts isolate immediately.
3/
Read 8 tweets
Peter English #FBPE Profile picture
15 Nov
@jackiecassell @SusanMichie there are some really difficult scenarios, eg ppl with mental health/disability/educational needs
/behavioural problems in homes. Unable to do masks or distancing. Ghastly/distressing for them and those who love them…
@jackiecassell @SusanMichie Maybe teachers, if we prioritise keeping schools open over control.

But,to get control of disease ASAP w vaccine, simple age criterion makes sense as main focus.
@jackiecassell @SusanMichie I am surprised we don't yet know enough about antibody levels and immunity… I'd be surprised if data didn't support "while your neutralising Abs are >x, you're almost certainly immune" and enough knowledge of speed of decline to say "you're safe for at least n months".
Read 4 tweets
Peter English #FBPE Profile picture
9 Nov
"Covid vaccine: First 'milestone' vaccine offers 90% protection"
bbc.co.uk/news/health-54…

JamesTGallagher
This is good news. Some thoughts about Covid-19 vaccinations and mRNA vaccines in particular.
2/11
The R0 for Covid-19 is about 2.5.

If it were 3 you'd have to get 2 out of every three people who would otherwise have caught it immune, so they don't catch it and pass it on. If it's less, you have to get fewer people immune in order to achieve population (herd) immunity .
3/11
Read 13 tweets

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