I've been getting questions from friends about what to do if their child gets sent from home to quarantine, after a case is identified in their class or 'bubble' (or whatever is the local term) 1/n
First point, be pleased that the exposure was detected. Imagine if it had not been. The information is power which helps you and others avoid infection, that is what the quarantine is for 2/n
the alternative (not testing) means undetected transmission in schools could introduce the virus to many households. Younger children *are* less likely to become infected and suffer severe illness, but they can transmit 3/n
A case in a school is one thing, transmission is quite another. It suggests the capacity for clusters of cases amplifying transmission. And if the school has been attempting mitigating infection control, that it can be improved 4/n
(sorry should be "mitigation through infection control") 5/n
A quarantining kid should, it goes without saying I hope, not have contact with other kids outside the household, but what about family members? Well there are ways to reduce the risk to them 6/n
And they're what we are familiar with. Masks indoors. Ventilation. Ideally not sleeping in the same room as others (people who become infectious at night will shed a lot to their sleeping audience) 7/n
hand washing. Like many others, I am not persuaded that fomites are an important transmission route in general, but I will take them seriously in this case 8/n
and testing. I'd love there to be rapid antigen tests available such that quarantine could be curtailed, or at least informed by daily testing. Even though incubation periods can be long, they mostly aren't. So if you test negative for days in a row after exposure that's good 9/n
If going for a PCR test, it is wise to wait awhile before going to get tested (4-5 days after exposure, others closer to this likely have a better read). Remember that you can get false negatives early on in infection 10/n
A negative test under these circs under the great majority of cases means you can relax. But I want to finish saying something about transmission 11/n
Transmission is what matters - remember that if you send your quarantined child into a learning 'pod' with other quarantined kids, you are increasing the risk they get infected 12/n
so do what you can to reduce transmission. There's really a lot. Even if interventions on their own are small, they are powerful in combination nytimes.com/2020/12/05/hea… 13/n
this is ending up sounding tired, partially because I am. But the whole point of distancing is that you assume you are infectious and protect your neighbors accordingly. So when we know someone is exposed, that's why quarantine is important 14/end

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More from @BillHanage

25 Nov
Will not be time for many of these and please understand may well be distracted so will miss put too many but given the thanksgiving holiday would like to should out to those like @ImpactMovie who have been admirable friends for months. Happy thanksgiving to you and yours!
I would add @SFDukie happy thanksgiving to you and yours - hopefully in a non generation mixing setting
Or the extraordinary @EIDGeek - this had been a bad year. Getting to know you better has been one of the better parts. Look forward to meeting in person, one day
Read 5 tweets
25 Nov
I’ve now looked at this news in more detail and thought about it. Comments follow 👇🏼
First this is good news in that it shows yet more evidence efficacy can be achieved, and in a vaccine setup we understand better than mRNA vaccines - no disrespect to any platform, but having more weapons in our arsenal is always going to be better
But what’s bad is the relentless media focus on the “up to 90% efficacy” which makes me irritable. This was a result from a mistake in the vaccine trial regarding dosage. Vaccine trials are not the sort of places you want to make mistakes
Read 10 tweets
18 Nov
A comment (to complement some parallel threads from @michaelmina_lab) on the value of rapid testing, even if it is imperfect. So how do you re open say... movie theaters in the midst of a pandemic where anyone could be infected, and many are at risk of fatal outcomes? 1/n
So bad things are that most movies theaters are indoors, probably poorly ventilated. Crowds. Lots of opportunities for close contact. A person at the peak of infectiousness could kick off a Superspreader event 2/n
If you could present reliable evidence you have been -ve in the last 24 hrs, well that would obviously be transformative. But wait - what if that test result is a false negative and there is a resulting false sense of security? That’s where the masks come in 3/n
Read 6 tweets
15 Nov
My test Thursday came back negative yesterday evening ~36hrs after the test which is much better than this, but still later than ideal 1/n
The reason for the test was exposure to a suggestive but non-specific symptom in a member of the household who was also tested 2/n
While waiting for the test result, all members of the household quarantined. Child did not go to school. Prevented any risk of transmission outside the household 3/n
Read 13 tweets
13 Nov
There's a lot of talk about 'preserving healthcare' as a primary goal of pandemic management. That's not wrong, but it begs the question of what exactly we mean by 'preserving healthcare'. I recommend this article in the @NEJM & will add a couple comments nejm.org/doi/full/10.10…
So for some 'preserving healthcare' means avoiding all ICU beds being occupied by the pandemic. This is obviously bad. It's also a very low bar. If we get even close to this, where do you put patients recovering from surgery? Or emergency ICU admissions for other things? 2/n
This is not a hypothetical☝️🏽. So let's say we stop short of crashing the ICUs with patients - we would still end up with shortages of skilled nurses elsewhere in the system, compromising healthcare. When they are redirected at the pandemic other care is affected 3/n
Read 11 tweets
13 Nov
Some of the replies to this have made it clear people still think Covid tests are all painful, and would avoid them. That's *not true*. This👇🏽is a swab for a Covid test, and a PCR test at that. And that's as far as it got into my nose 1/n
We've come a long way since the early days of the pandemic. Then, concerns about sensitivity meant that tests were done on nasopharyngeal swabs, because we were not confident that a nasal swab like this would be accurate enough 2/n
The nasopharynx is right at the back of the nasal cavity, a swab like this is the sort of thing you'd remember. And if you don't know much about test sensitivity it is the starting point. As time goes on, we can ask whether you lose sensitivity with other sampling methods 3/n
Read 7 tweets

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