Some of the replies to this have made it clear people still think Covid tests are all painful, and would avoid them. That's *not true*. This👇🏽is a swab for a Covid test, and a PCR test at that. And that's as far as it got into my nose 1/n
We've come a long way since the early days of the pandemic. Then, concerns about sensitivity meant that tests were done on nasopharyngeal swabs, because we were not confident that a nasal swab like this would be accurate enough 2/n
The nasopharynx is right at the back of the nasal cavity, a swab like this is the sort of thing you'd remember. And if you don't know much about test sensitivity it is the starting point. As time goes on, we can ask whether you lose sensitivity with other sampling methods 3/n
This shows that swabs from the outer bit of the nostril (like the one I had) or mid-turbinate (a bit further in) are very nearly as sensitive as an NP swab (>90%). And substantially more comfortable 4/n nejm.org/doi/full/10.10…
It's not just that they're more comfortable. Patients can administer them themselves, and they're less likely to sneeze while being swabbed, which protects the people doing the swabbing and means we don't burn through PPE so quickly 5/n
But the upshot is that people should feel comfortable getting tested if they are concerned they've been exposed, or they might be infected. Testing is great. It's the flashlight that shows us where the enemy is 6/n
of course we do need results in good time to make use of them, and PCR is slower than antigen testing (paging @michaelmina_lab). That said, you should feel comfortable getting tested. We're past Halloween and there's no call for horror stories about swabs 7/end

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More from @BillHanage

13 Nov
There's a lot of talk about 'preserving healthcare' as a primary goal of pandemic management. That's not wrong, but it begs the question of what exactly we mean by 'preserving healthcare'. I recommend this article in the @NEJM & will add a couple comments nejm.org/doi/full/10.10…
So for some 'preserving healthcare' means avoiding all ICU beds being occupied by the pandemic. This is obviously bad. It's also a very low bar. If we get even close to this, where do you put patients recovering from surgery? Or emergency ICU admissions for other things? 2/n
This is not a hypothetical☝️🏽. So let's say we stop short of crashing the ICUs with patients - we would still end up with shortages of skilled nurses elsewhere in the system, compromising healthcare. When they are redirected at the pandemic other care is affected 3/n
Read 11 tweets
3 Nov
On the eve of the election, this paper from me and others lays out the impact of the federal government on the pandemic, it's not good link.springer.com/article/10.100… 1/n
1st the failure to prevent introductions. Lots of dramatic posturing against China, while the virus found ample opportunity to enter the country from Europe. Pandemics are, by definition, global 2/n
2nd Have you noticed the appalling numbers of healthcare workers who have lost their lives? We have known all along one of the most important ways to help them is Personal Protective Equipment or PPE khn.org/news/lost-on-t… 3/n
Read 7 tweets
22 Oct
The severity of covid varies greatly by age, with risks of death in young people often said to be equivalent to those of flu. This is one of the most pernicious pieces of misinformation I have noticed in the pandemic. This is why 1/n
first of all, let me be clear that this is *only* based on deaths. There is plenty accumulating evidence that ~10% of people can have long term illness (long covid) lasting for months and this includes young people. I know some. You may too 2/n
It is correct that younger people are much less likely to die from covid, but younger people are much less likely to die period - from covid *or* flu. So how many younger people typically die of seasonal flu? Fortunately @CDCFlu has asked that question for us 3/n
Read 10 tweets
16 Oct
The changing political geography of the pandemic in the US. In the spring the densely populated deep blue NE was hit hard, but since July things have flipped and cases and deaths are now highest in rural GOP voting areas. Featuring work from us
washingtonpost.com/health/2020/10…
It also quotes @AliHMokdad who says, rightly "it didn’t show up immediately in rural communities,” he said. “And then people in these communities felt, ‘That’s not us, that’s the big cities.’ They let down their guard.” But there's something else here
the introductions to large urban areas are predictable, simply because of the numbers of opportunities, while for smaller rural communities it is more random. But given time the virus will get there eventually
Read 7 tweets
14 Oct
With many other experts in infectious disease and allied fields, I'm proud to sign and have done my bit to help write this in @TheLancet which explains the *actual* expert consensus on the #COVID19 pandemic and the need for action marlin-prod.literatumonline.com/pb-assets/Lanc…
The letter states as clearly as can be that approaches to the pandemic that seek immunity through natural infection are dangerous, and explains why
This is a collaborative effort with many brilliant people, but @dgurdasani1 deserves special mention, for the tireless way she combined viewpoints and expertise from many different fields to build this statement of *consensus*.
Read 7 tweets
11 Oct
This is a very interesting deep dive into the controversial route Sweden took through the spring and summer of the pandemic (HT @AliciaJWeston). A few things stand out... sciencemag.org/news/2020/10/i…
First Sweden did not ‘do nothing’, there were sensible steps taken including restrictions on large gatherings (implemented early on), and there was considerable evidence of altered movement patterns. High schools and universities remote learning too. However...
There was still a very large, very rapid surge in healthcare demand and lot of deaths in a short period during the spring. Mortality was concentrated in nursing homes - which *are* part of the continuum of healthcare. Figures are not easy to interpret because of issues with...
Read 9 tweets

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