One of the lines of evidence on transmission is in this tweet. One of the mutations in the new variant (deletion of amino acids 69 & 70 in spike) by coincidence causes 1 of the 3 channels of a widely used PCR test to drop out, giving us a way to track it in real time. (thread)
First, an important note: this assay has probes in two other parts of the SARS-CoV-2 genome, and they are not affected by the new lineage. Since not all three channels have to "light up" to declare a positive, this doesn't significantly affect test sensitivity.
Our sequencing data lags by about 2 weeks, but this read-out at test sites only lags by 24 hours, so we can see how fast the variant spreads in real time. Figuring this relationship out in the past few days was one thing that clarified the seriousness of the situation.
There are also sophisticated models (briefly mentioned at the presser) about exactly how much faster this variant spreads. But this graph looks a lot like the most recent xkcd comic: xkcd.com/2400/

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More from @jcbarret

20 Dec
One of the key questions about the new variant (B.1.1.7) is whether there is conclusive evidence that it is more transmissible. I don't think we are absolutely certain yet, but I am pretty confident that it is more transmissible. (1/N)
First, what's the alternative hypothesis? A lineage can get "lucky" and increase in frequency because it happened to be present in local circumstances that favour growth (e.g. poor compliance with social distancing). (2/N)
A good example of this is 20A.EU1 that spread widely throughout Europe after the summer (see excellent @firefoxx66 paper: medrxiv.org/content/10.110…). So far, evidence seems to suggest that was just a "lucky" case, rather than a biological change in the virus. (3/N)
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