1/ THIS was an email sent 9yrs ago—from an unknown scientist with entrepreneurial ambitions.
We didn’t reply
9yrs later we + others (including Bill Gates, Jim Simons , sovereign wealth funds + top biotech VCs)—have put over $250M in companies @ipeikon has helped start with Lux
where Columbia U’s Tom Maniatis (to my right) tipped off Lux me + @AGoulburn —
to the enormous potential of Cryo-EM as cutting edge technology for science...
5/ Here are some excerpts from exclusive Lux series—
explaining the science + tech + people behind Kallyope...
“The gut-brain axis is the bi-directional communication between the gut + the brain. It’s composed of neural circuits + hormonal circuits...”
6/ The brilliant @ThornberryNancy explaining the science + tech of cutting edge venture: Kallyope.
“We’re leveraging a # of advanced technologies—to create a comprehensive map of gut-brain circuits: single-cell sequencing, organoids, optogenetics, chemogenetics...”
7/ “There’s no question that important aspects of physiology are mediated by the gut-brain axis—there’s a biochemical basis for things like a GUT FEELING, for example.”
“In the same way that I might sit down at a piano and hit a note and it produces a sound or a chord...
8/ “In the same way that I might sit down at a piano and hit a note and it produces a sound or a chord...and it produces a different sounds, the idea is that if you can use gut-restricted molecules, that you are basically targeting different notes that you can play in the brain.”
-in SCIENCE via methods of conjecture + refutation
-in PRODUCTS via better, cheaper, faster, more convenient
-in INVESTORS in self-interest competing to be earlier than others, funneling funds MOST likely to be lost for slim chance of big gains
3/ Which have driven
-global communication costs to near ZERO
-processor computation + video rendering to exponentially better quality
-frictionless exchange of scientific information to model in DAYS(!) + manufacture in MONTHS(!) a vaccine
-with a system of safety + testing...
2/ Cancel monthly bills for cable + phones + internet + gym memberships + magazines + newspapers + substack subscriptions!
And cancel restaurants too––
food + fun should be free for all!
3/ Cancel car payments + cancel airline tickets––travel should be free for everyone.
Cancel music subscription services + podcasts.
Cancel Spotify + Apple.
Cancel royalties to artists.
No 1 artist should be more popular than the 99%!
Cancel ticket sales to concerts + sports.
"It's like trying to swim against the current of the Pacific Ocean. We knew we were drowning, and we were just going to try to keep swimming as long as we could"
RTJ4
Jay Electronica—written testimony + act 2
Aesop Rock—spirit world field guide
unlocked—denzel curry x kenny beats
Marlowe 2
Eminem—Music to be..
Alfredo—alchemist
Revenge of the Dreamers
Clams Casino—esp ‘unchain me’; Lost Boys🎥
Pray for Paris
Marlowe 2
3/ the Clams Casino instrumental is solid but this track is more personal, he samples Cry Little Sister from “Lost Boys”—i was 9 and in middle of cross-country custody battle and LOVED this movie and well––wanted to be a vampire in Kiefer Sutherland’s gang open.spotify.com/track/0RokJnY3…