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Eric Feigl-Ding Profile picture
@DrEricDing
Dec 27, 2020 • 10 tweets • 5 min read • Read on X
BREAKING—95%—new data from Oxford/AstraZeneca vaccine shows 95% efficacy & is “100% effective” in preventing severe 🏥illness, says AZ CEO. That’s on par w/ Moderna & Pfizer. No official data yet, but UK 🇬🇧 said to likely approve in days. HUGE🧵. #COVID19
thetimes.co.uk/article/covid-… Image
2) As u know, Oxford was unhappy with the last trial because of the dosing quirk with the half dose / full dose issue that led to a split finding of 90% in the half-full dose, but 63% in the full-full dose. Hence they said last month they will redo with a new trial.
3) Recall the original Phase 3 trial last month was still quite good. 70% overall (averaging across all doses), or 90% in the half-full dose. Oxford was the FIRST to publish formally in a journal! Moderna & Pfizer didn’t publish until later even though they were approved first.
4) Why is the Oxford #COVID19 vaccine so critical for the world?

—8-10x cheaper than Moderna/Pfizer

—Does **NOT** require any freezing! Only simple refrigeration.

—Is the #1 vaccine on order worldwide.

➡️Hence a cheap, easy to handle vaccine at 95% is huge!! Image
5) How much of the world depends on the cheap and easy to transport Oxford/AZ #COVID19 vaccine? Almost 3 bil doses—40% of the entire world 🌎’s order of 7.38 bil doses—by this one vaccine. Everyone is counting on this.

300 mil US & 400 EU is also the largest orders for them. Image
6) Some are asking why/how the new Oxford/AZ result is different — they retested the vaccine from the previous half-dose/full-dose regimen that had the earlier 90% efficacy.

To be clear, it wasn’t a safety issue before. Some critics said it was dumb luck or <55 age. Hence retest
7) My earlier thread 🧵 walks thru the denser epidemiological issues with the previous Oxford-AZ low dose trial that got the previous 90% efficacy. In short, they wanted to rerun to make sure. And the 90% result was NOT post-hoc dredging for strong funding, it was pre-registered.
8) The Oxford/AZ vaccine is not an mRNA vaccine like Moderna or Pfizer/BioNTech’s. Oxford relies on a neutralized adenovirus that is harmless, but “hitchhike” tagged with the spike genes of #SARSCoV2 coronavirus to train our cells to the spike protein. research.ox.ac.uk/amp/Article/20… Image
9) Oxford scientists say this on the adenovirus vector approach: “ChAdOx1 was chosen as the most suitable vaccine technology for a SARS-CoV-2 vaccine as it has been shown to generate a strong immune response from one dose in other vaccines...”
10) “It has been genetically changed so that it is impossible for it to grow in humans. This also makes it safer to give to children, the elderly and anyone with a pre-existing condition such as diabetes. Chimpanzee adenoviral vectors are a very well-studied vaccine type”.

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More from @DrEricDing

Eric Feigl-Ding Profile picture
May 16
⚠️NO RARE BEEF!—@USDA suddenly admits (after Q&A pestering) that 120F cooked beef🥩patties experimentally inoculated with H5N1 virus still had surviving virus.

➡️“Cooking to… 120° F did show that there was virus still in the cooked hamburger patty, although at reduced levels." Image
2) Initially the @USDA only stated that no virus survived cooking to 160 F and 145 F. But they didn’t volunteer the 120 F rare cooking temperature results! Only after more questioning did they reveal 120 F virus survival. But so many folks eat rare meat! 🥩 DISCLOSURE CRITICAL!
3) here was the initial USDA press conference announcement. Made no mention of the results for virus levels in beef at lower temperatures.
Read 11 tweets
Eric Feigl-Ding Profile picture
May 15
Dear Raw Milk drinkers— behold your future:

“West Virginia politician falls ill due to drinking unpasteurized milk after helping pass a law that legalized raw milk.”

eater.com/2016/3/9/11186…
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The FDA has completely dropped the ball on stopping raw milk trade.
3) Folks— famous Typhoid Fever outbreak in UK 🇬🇧 — caused by RAW MILK 🥛… legendary case from 1937.

We don’t learn from history do we? We just have to learn the hard way all over?
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Read 8 tweets
Eric Feigl-Ding Profile picture
May 11
UPDATE—Solar Storm hits the highest level of G5, the first in over 2 decade, which could knock out power to grids and disrupt GPS. A coronal mass ejection of G5 was also what the infamous “Carrington Event” was in 1859. But it depends on magnetic 🧲 polarity of each CME wave. NOAA warned earlier today that CME storms tend to be even stronger on the latter half of a storm wave. Let’s hope the next two days won’t be as extreme as the Carrington Event. #solarstormImage
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2) the CME does create super gorgeous auroras.
3) We are potentially in for a wild weekend. We haven’t been hit with this many CMEs in a long ass time. Nor has NOAA alerted with a GEOMAGNETIC STORM WATCH in over 20 years.
Read 8 tweets
Eric Feigl-Ding Profile picture
May 10
⚡️INBOUND SOLAR STORMS—5x mega coronal mass ejections - CMEs - that can knock out power are going to be slamming at Earth 🌍 between Friday and Sunday this weekend. Earth has only been hit with 3 previous severe CMEs in last 4 years. But we are gonna get 5x G4 CMEs in 3 days!😳 Image
2) Let this sink — this is the first GEOMAGNETIC STORM WATCH since 2005!

Folks - this is serious - it can knock out not only electricity but it can theoretically knock out airplanes ✈️ too! Image
3) Folks- it’s possible. Not only can it cause higher radiation and knock out communications, but a strong CME can knock out airliner avionics. “according to reports by aviation regulators, the issue is not whether it will happen, but when” 😳 thedailybeast.com/how-a-solar-st…


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Read 13 tweets
Eric Feigl-Ding Profile picture
May 10
Things are not going well with whooping cough (pertussis). Childhood vaccinations plummeting in the UK 🇬🇧, and kids also have weakened immune systems post-COVID. And it’s not even autumn 🍂.

HT @1goodtern Image
2) Also… let’s not forget the “m” word. Because masks do work if society takes it seriously.
3) unless we systematically solve the. chronic lack of public health infrastructure, new outbreaks will continue. We shouldn’t just learn to live with it.
Read 5 tweets
Eric Feigl-Ding Profile picture
May 10
⚠️New sudden outbreak of MERS coronavirus with HUMAN TO HUMAN transmission—WHO has put out an outbreak bulletin regarding 3 cases in Saudi Arabia 🇸🇦 who contracted MERS (with zero contact with camels). All 3 were hospitalized and intubated. Index case has died in just 11 days from the onset of cough and a runny nose. ➡️Here where it gets interesting—the other 2 cases, found via vigorous contact tracing—both likely contracted it from the index case in the hospital—one shared a hospital room with the index case, while the other merely visited the same hospital’s ER—but he was NOT in the same hospital ward as the index case! Given second case was in a completely separate ward of the hospital, it makes me think it was likely #airborne transmission.

Shouldn’t we all masking in hospitals? @CDCgov’s idiotic HICPAC committee that sets hospital safety standards meantime wants to water them down. Someone should share this with the HICPAC folks, thanks. And demand @CDCDirector to get serious about public health again.

who.int/emergencies/di…Image
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2) previously, WHO’s Feb bulletin of Aug 2023-Feb 2024 only reported 4 cases, 2 had camel🐪 contact. None of the previous 4 had any linkages (ie no human to human transmission evidence). Thus, this new hospital-derived outbreak is concerning.
who.int/emergencies/di…
3) it seems the Index case’s only overlap with Case #3 was on April 4th— the day they both went to the same hospital’s ER. But otherwise they were in different wards. And by the time the 3rd case went to the ICU on April 15th, the index case was already dead (died on April 11th). So it wasn’t ICU exposure. It was the ER—➡️why which why EVERYONE NEEDS TO WEAR MASKS IN THE ER DAMNIT! 🔥Image
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Read 5 tweets

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