So, people have taken the time to translate my explanation of mRNA vaccines into a bunch of different languages. I’ll post them in this thread in case you have a non-English friend, relative, potty-mouthed grandma who’d like to know how this vaccine works.
I think there’s Hungarian and Arabic versions floating around but I’ve lost them. Also, someone told me about a Romanian translation on Facebook. If you find them, let know and I’ll post them here. (I don’t care if they gave me credit or not, just want the info out there.)
China recently approved the Sinovac vaccine and since apparently this is what I do in my spare time now, let’s talk about how that one works!
It works in yet a different way than the mRNA (Pfizer / Moderna) or the AstraZenica vaccines.
The Sinovac vaccine is a more traditional vaccine type. It’s an “inactivated” vaccine. That’s different from another traditional vaccine type: an “attenuated” vaccine.
I should take a moment to clarify the difference.
Think of an “attenuated” vaccine (also sometimes called a “live” vaccine) is when you take a virus and make it way less dangerous. It’s basically your body fighting against this guy.
Some have asked me about how the AstraZenica vaccine is different than the mRNA vaccines. @ScientistSwanda does a great job here describing it. The vaccine is still all about the asshole protein, your body just produces it in a different way.
I guess to describe it in the theme of my other threads:
Scientists took a totally different virus that doesn’t hurt humans. They cut out most of the virus DNA until what was left was a mostly empty shell. (The virus is now basically us by the end of this godforsaken year.)
So you take this basically empty shell of a virus and you throw in the code to make the infamous asshole protein. So now you’ve got a toothless virus that can’t do shit to you except make asshole proteins.
COVID-Steve has a particular weak spot. Without that protein, he’s not nearly as effective. That’s fortunate. It makes him easier to target. Steve also tends to be slower to change (or mutate).
Not every virus has a weak spot like that.
Influenza is a whole category of jerks with lots of different strains. They mutate quickly. They mix and match. They have different proteins on the outside. (That’s part of what the names of them mean: H1N1 refers to the names of the proteins on the virus, as an example).
Via @IneffectiveMath, Slater Koekkoek played 3rd pairing minutes for Chicago last year (as he’s mostly done for his career). Last year the team did well in shots and goals with him on the ice. He started a lot in the D-zone & took a lot of penalties.
Via @puckiq, he wasn’t particularly sheltered against elite competition. More middle of the road. In Tampa he played against less elite competition in a more traditional 3rd pair role.
I think it’s fair to say Edmonton signed a pretty solid 3rd pairing defender. He ‘might’ do okay on the 2nd pair but we don’t have a great sample size with him there.
Darnell Nurse on screen wearing medical scrubs. “Hi, I’m Darnell Nurse. As a Nurse, I’m here to tell you how the vaccine works. Let’s say there’s a virus.”
Relevant notes to questions that people have asked me:
- Slightly less effective in elderly people (who usually have a weaker immune response) but still 86% effective. Not as good as 94% for the general population but still very solid.
Pregnancy: Pregnant women weren’t allowed in the study but 13 women got pregnant during the study. About half in the vaccine group and half in placebo. None of them have given birth yet though. So we’ll see.