Thread by @cedricboeckx

Very pleased to share a new preprint, with @AGMAndirko @juanandres_mp @polvere7 @MKuhlwilm @gtesta72, where we estimate the time of emergence of derived variants, seeking to offer more precise answers to time-sensitive hypotheses re: human evolution. 1/
biorxiv.org/content/10.110…

We find evidence for very early mutations impacting the facial phenotype, and much more recent molecular events linked to specific brain regions such as the cerebellum or the precuneus. 2/

I enjoyed working on this with my students @AGMAndirko & @juanandres_mp in otherwise difficult circumstances (lockdowns). They are terrific researchers. I am thankful for the opportunity to work again with friends @MKuhlwilm @polvere7 @gtesta72, the best part of the job, IMO. 3/

This works builds on previous results of ours:
my previous work with @MKuhlwilm & 4/ nature.com/articles/s4159…

our work with @polvere7 & @gtesta72 on BAZ1B 5/ advances.sciencemag.org/content/5/12/e…

We also build on the important work of P. Gunz & @jjhublin and their colleagues: 6/
nature.com/articles/natur…

We were also inspired by the issues raised by @DrEleanorScerri and colleagues in that wonderful paper: 7/
cell.com/trends/ecology…

and also the reflections by @ChrisStringer65 in this paper, which I like a lot: royalsocietypublishing.org/doi/full/10.10…