Thread by @BaccarelliAA

Very interesting data on the 8+ year outcomes of T32 training program. See thread below. #Epitwitter #training #T32 #AcademicLife #AcademicChatter @NIH 1/9
nexus.od.nih.gov/all/2021/02/01…

The shocking part to me is that only 12% of T32 trainees eventually became PIs of R01s. I truly expected much higher proportions. Was this wishful thinking? 2/9

Important to point out that the study covers T32 trainees who matriculated btw 1995-2009 and were followed up until 2017. Hence some, especially in the later cohorts may be still due to be R01 PIs. 3/9

Multivariable analysis show that women had 32% lower success rate to getting an R01 compared to men. Also older trainees (36+) had less than half R01 grant getting. 4/9

The T32 trainees were divided in three matriculation cohorts (1995-1999, 2000-2004, 2005-2009). Those in earlier years had better chances, purportedly due to being contemporary to the NIH budget doubling. However, does the later cohort need longer than 8 year follow up? 5/9

Lots of great graphs showing unadjusted comparisons. However, please be aware that some are deceiving. For instance, MD/PhD seem to do much better than PhD in unadjusted graphs, but that is just because more women than men were PhD. 6/9

The multivariate analysis shows that those with a PhD do better than both MD/PhD and MD (listed from highest to lowest success) when adjusting by gender. 7/ 9

Finally, the article makes a strong point about K01 grantees being much likely to get an R01. However, is that causation or just association? People who get a K01 might be then getting an R01 just because they are better scientist and/or grant writers? 8/9

Lots to think about. Anything else I have missed? Your thoughts? What actions these data may prompt? 9/9