𝙏𝙃𝙀 π™ˆπ™π˜Ύπ™ƒ π™π™Šπ™π™‚π™Šπ™π™π™€π™‰ 𝙍𝙑

1/5
Dif Approaches to Optimizing PEEP

PEEP and RV Function
Clifford Greyson @SCCM #CCC50

#PedsICU #PedsCICU #PedsCards
2/5

▫️Frank-Starling law is more reflective of LV physiology
▫️ RV normally unstressed at end diastole
▫️ RV maladapts to volume overload overtime
▫️ Distorted RV balloons impedes LV
▫️ RV perfusion occurs during ventricular systole
▫️ Vicious cycle πŸ”„ of RV dysfunction
3/5

RV afterload affected by
▫️PVR
▫️Pul vascular compliance
▫️LAP

all compromised with excessive PEEP
4/5

β€œmoderate” PEEP can recruit alveoli, reduce hypoxia and improve Pul vasoconstriction

how CAN we tell ❓

▫️clinical improvement:
systemic pressure
▫️ ECHO: CO increase
5/5

#COVID19 in AICU has demonstrated that the RV is a major player

figuring out what works is just not
so easy ❗️

mortality for hospitalised patients on organ support and survival to hospital discharge ‡️

sccmcovid19.org
#SCCMDiscovery

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