1/ On @CBSNews this evening with 3 of my favorite epidemiologists: @ashishkjha @mtosterholm @DrTomFrieden. The editing of my interview is a bit misleading. For clarification:
2/ The UK B.1.1.7 variant is more contagious and *may* be more virulent. If someone is infected with a more virulent strain, that means their risk of more severe disease and death is higher.
3/ The UK B.1.1.7 variant is definitely more contagious / transmissible / infections, which means that if you're exposed, you're more likely to get infected. That means more cases, which equals more disease, hospitalizations, and death.
4/ To be clear, the COVID vaccines remain effective against the variant strains, BUT we have seen a reduction in their effectiveness. This reduction is A RED FLAG. We cannot let these variants spread. We cannot allow the virus to spread.
5/ The more a virus spreads, the more it will mutate. Mutations are how viruses evolve to escape our defenses. We don't want to let the virus mutate to the point that our vaccines no longer protect us.

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Keep Current with Céline Gounder, MD, ScM, FIDSA

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More from @celinegounder

7 Feb
1/ Should we give as many people one dose of the Pfizer and Moderna vaccines as possible? Or half as many people two doses of vaccine? It’s a data-free zone.
2/ Here’s the Pfizer COVID vaccine clinical trial data. Study participants got their 2nd dose at 21 days. We only have data on how well one dose of the Pfizer vaccine was at protecting against COVID during that 21 day / 3 week period after the first dose. nejm.org/doi/full/10.10… Image
3/ We don’t know how good or how long that protection would last if someone did NOT get that 2nd dose at 21 days.
Read 17 tweets
3 Feb
1/ “When I say ‘experts’ in air quotes, it sounds like I’m saying I don’t really trust the experts,” @NYGovCuomo said of pandemic policies. “Because I don’t.”
nytimes.com/2021/02/01/nyr…
But he does trust lobbyists, big private hospital systems, and paid consultants like Deloitte.
2/ Because we should trust consultants like Deloitte? Who charged the US government $44M to build a dysfunctional IT system to track COVID vaccination? technologyreview.com/2021/01/30/101…
3/ Why is @NYGovCuomo opening restaurants now? Monied interests. nytimes.com/interactive/20… If he really cared about people working in restaurants, he'd be focused on providing them with the economic and social supports to weather the pandemic safely. justhumanproductions.org/podcasts/ep-51…
Read 8 tweets
2 Feb
1/ We need to do better on equity in vaccine rollout. But that means (a) we've got to solve the right problem, and (b) we need the people and tools to solve the problem.
2/ Is it access or is it hesitancy that's led to less vaccination among communities of color? How do the demographics of healthcare workers and the residents of long-term care facilities, who had earliest access, compare with those of the same age in the community at large?
3/ Among healthcare workers who had access to vaccination in their workplace (note that home health aides, out-patient healthcare workers, and others may not have had access at work), were the demographics of those getting vaccinated skewed relative to the total population?
Read 8 tweets
1 Feb
1/ Thanks, @UnivisionNews for helping get good information out about the COVID pandemic.
2/ Translation here:
"This came to my attention. For me, this is an erroneous message for the citizens of Mexico and for the players, young people are doing anything and everything. The doctor Celine Gounder, who was assigned by the incoming @WhiteHouse in November,
3/ "...the new @POTUS, she had the opportunity to write to answer us:
'We cannot rely on natural immunity. We have seen reinfections following natural infection. Positive antibody tests demonstrate prior infection, NOT robust, long-term immunity.'
Read 6 tweets
31 Jan
1/ NYC released its data on COVID vaccinations by race today. Among adults 18+, those vaccinated skew whiter. Black and Latinx NYCers are vaccinated at disproportionately lower rates. www1.nyc.gov/site/doh/covid… Image
2/ Among adults 18-64, those vaccinated again skew whiter. Asians slightly overrepresented (perhaps because many work in healthcare?) Black and Latinx NYCers ages 18-64 are vaccinated at disproportionately lower rates. Image
3/ Among NYCers 65+, those vaccinated again skew whiter. Asians slightly underrepresented (perhaps less likely than older whites to be long-term care facility residents?) Black and Latinx ages 65+ are vaccinated at disproportionately lower rates. Image
Read 5 tweets
28 Jan
1/ New COVID variants are emerging:
- B.1.1.7 from the UK: more transmissible, possibly more virulent. Even if not more virulent, more transmissible = more infections, more disease, more hospitalizations, more death.
2/
- 501Y.V2 from South Africa: immune response elicited by both natural infection & vaccines may be blunted with lower neutralizing antibody activity BUT the Pfizer/Moderna vaccines still appear to be effective. We should soon have data on the AstraZeneca and J&J vaccines, too.
3/ P.1 from Brazil: More transmissible like B.1.1.7 variant from UK. Blunted immune response like 501Y.V2 variant from South Africa. washingtonpost.com/world/2021/01/…
Read 7 tweets

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