Thread by @Mangan150

The high consumption of seed (vegetable) oils could play a significant role in severe Covid disease, and might even explain between-country variation in mortality.

Thread👇

Omega-6 fatty acids are abundant in seed oils and their consumption leads to a pro-inflammatory state, in turn leading to a cytokine storm which is associated with Covid mortality.

Excessive consumption of linoleic acid, the most abundant component of seed oils, leads to imbalanced tissue fatty acids.

pubmed.ncbi.nlm.nih.gov/28535956/

The more omega-6 from linoleic acid consumed, the higher the proportion in tissues.

These omega-6 in tissues are transformed into pro-inflammatory eicosanoids (cytokines) sciencedirect.com/science/articl…

Aspirin blocks production of pro-inflammatory eicosanoids, which explains why it dampens inflammation and relieves pain.

Aspirin use is associated with about half the risk of ICU admission and death from Covid.

journals.lww.com/anesthesia-ana…

Omega-3 fatty acids (from fish and fish oil) lead to production of anti-inflammatory cytokines.

A strong inverse trend exists between omega-3 blood levels and death from Covid.

sciencedirect.com/science/articl…

Anti-inflammatory molecules called resolvins are made from omega-3 fatty acids
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jci.org/articles/view/…

A clinical trial is underway to test whether giving omega-3 fatty acids is helpful in Covid disease.

frontiersin.org/articles/10.33…

"Physicians should measure their patients’ fatty acids and recommend decreasing the intake of foods rich in omega-6 fatty acids and increasing the intake of omega-3 fatty acids"

That means decreasing seed oil consumption and increasing fish consumption
karger.com/Article/FullTe…

Cyclooxygenase activity is upregulated in aging. This is the enzyme that produces pro-inflammatory cytokines and which is blocked by aspirin.

Might explain some of the relation between aging and mortality.

academic.oup.com/biomedgerontol…

Therefore, low or no consumption of seed oils and higher consumption of fish or fish oil may help protect against Covid, and may explain differences seen in susceptibility of patients and populations to Covid.

Those of you new to the fact that seed/vegetable oils are harmful to health, and wondering what you can safely use, check out my article roguehealthandfitness.com/how-to-choose-…