I missed this disturbing/fascinating bit on leaked docs w/ quality control issues from the Pfizer vaccine:
bmj.com/content/372/bm…
A reminder that just because Big Pharma hits a home run, they (& the medical-industrial complex) are not suddenly warm and fuzzy trusted friends. 1/3
bmj.com/content/372/bm…
A reminder that just because Big Pharma hits a home run, they (& the medical-industrial complex) are not suddenly warm and fuzzy trusted friends. 1/3
I wish I understood mRNA vaccines better, but the bottom line appears to be:
these mRNA particles tucked in those lipid nanoparticle membranes are frail;
they degrade easily;
and you want them to be intact when they hit our cells, so the proper protein complexes are formed. 2/3
these mRNA particles tucked in those lipid nanoparticle membranes are frail;
they degrade easily;
and you want them to be intact when they hit our cells, so the proper protein complexes are formed. 2/3
Since "commercial grade" seems to be 75-80% intact mRNA, and the "bad" batches were around 55%, that would imply about a third less production of proper spike-like proteins.
Not from zero to something, but from 25% to 45%.
So - I doubt these are forming *dangerous* proteins.
Not from zero to something, but from 25% to 45%.
So - I doubt these are forming *dangerous* proteins.
Just forming fewer of the *planned* proteins.
Whether this would results in a clinically significant efficacy loss for these batches, I also rather doubt, but it's possible.
Not a reason to pass on mRNA vaccines.
The lack of transparency is concerning, though, if not surprising.
Whether this would results in a clinically significant efficacy loss for these batches, I also rather doubt, but it's possible.
Not a reason to pass on mRNA vaccines.
The lack of transparency is concerning, though, if not surprising.
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