2/10 The MAJOR caveat here is that we are only looking at short-term impact. Long-term impact is going to take a while to assess
3/10 What would we expect to see if lockdowns caused large numbers of deaths?
Well, lots of COVID+lockdown would = many deaths, and no COVID+lockdown would ALSO = many deaths
4/10 If COVID was relatively safe, and lockdowns harmful in the short term, we'd also expect to see that lots of COVID and NO lockdown would be associated with FEW deaths
5/10 The first situation (COVID+lockdown) is obviously associated with many deaths. Tons of examples across the world to look at using this excellent paper on excess mortality medrxiv.org/content/10.110…
6/10 However, when we look at NO lockdown, and lots of COVID, we see a similar issue. Lots of excess mortality that is probably down to the virus itself
7/10 As for places WITH lockdowns and little/no COVID?
Well, the numbers look very different. Few excess deaths if any at all
8/10 These numbers are pretty similar across different investigations of excess mortality - in fact, it appears that lockdowns where there's NO COVID are associated with ~fewer~ deaths that expected
9/10 This doesn't mean that lockdowns work, or that they're perfect, or any such nonsense
It doesn't even mean that they definitely don't kill people (remember, short-term)
10/10 It DOES mean that the best current evidence suggests that lockdowns in and of themselves are not associated with detectable increases in mortality
They may even REDUCE deaths overall
11/10 Small addendum - lockdowns could still be bad if they saved lives, the point here is that we are completely lacking the evidence that we'd expect to find if lockdowns caused many deaths as some claim
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Your daily reminder that "I'm pro-vaccine except for THIS one" is literally the most common anti-vax line there is
The second most common line is "I'm pro-vaccine but I'm also pro informed choice" usually followed by a slew of lies and misinformation portraying vaccines as dangerous
So many replies missing the point. There's a big difference between common talking points and actions - most anti-vaccine advocates SAY they are only against one vaccine but then come up with similar arguments against ALL of them
Interesting update on this paper published that purported to show that staying at home doesn't reduce COVID-19 deaths: less than a week after publication it already has a warning from the editors
Also, the authors appear to have responded to my twitter thread that was automatically uploaded to Pubpeer, which is pretty fantastic. Not sure this helps their case tho
"This is the best data available" is not really a defense about using inadequate data. If you don't have the data to answer a question, then it's not a surprise that your study fails to find an effect I think
I think convalescent plasma will end up being a chilling message for future pandemics about the importance of research. At this point, it's been given to 100,000s+ of patients, but we only just discovered that it's probably not beneficial
Unlike hydroxychloroquine, which was always more political than scientific, CP was a good bet that people used because it was hopefully better than nothing
This should not be the default position. There is likely only a modest marginal benefit for rich countries from vaccinating young people, while developing nations would benefit enormously from these doses
Don't misunderstand - I think eventually most people should be vaccinated (including youths), but the benefit to the US of vaccinating 100% of its citizenry right now pales in comparison to the benefit of sharing those vaccines with other nations
People are missing the point. I'm not saying that the US should not vaccinate people, but the benefit to the US (and other rich countries) of vaccinating everyone before sharing *at all* is tiny compared to the benefit that those doses could have
@VPrasadMDMPH@CT_Bergstrom My favorite part of this is that we can actually do a fairly basic empirical test of whether the idea that twitter royalty is required to be a FB fact-checker is true, or whether it's simply a correlation due to pandemic expertise by looking at pre-pandemic follower counts
@VPrasadMDMPH@CT_Bergstrom Of the people quoted for the healthfeedback piece, the median number of twitter followers was 4,514, with two people having well below 1,000 prior to COVID-19. The mean is skewed up to 35k by Topol