Alina Chan Profile picture
17 Mar, 22 tweets, 9 min read
Chatted with @schmidtwriting for his new @undarkmag article on the traps and dangers of advocating for an investigation into potential lab origins of covid-19. #laborigins #OriginsofCOVID
I think this piece by Charles @schmidtwriting was particularly well written because of how balanced it is. There were parts that I didn't like and had to grapple with. A lot has happened in the last year since I started looking into the evidence surrounding the #OriginsofCOVID
It comes at a time when the WHO-China team is expected to release their full report in the coming week(s). And @JamieMetzl and ~two dozen scientists (me too!) have posted a letter in the @WSJ pointing out major major flaws in the WHO-China not-an-investigation joint mission.
The article points out that there are really 2 camps right now. It is not natural origins vs lab origins vs #PopsicleOrigins

It is (1) lab leak is plausible and must be investigated vs (2) SARS2 almost certainly natural so lab origins can be dismissed without real investigation.
But in each camp, there are disagreements.

Not everyone who thinks lab origins are plausible are on the same page. There are insane theories.

Not everyone who sides with EcoHealth thinks lab origins are conspiracy theories. (Some even think lab origins should be investigated.)
Speaking from the camp that thinks lab origins should be investigated, I advocate for scientists to please put out your own independent, original statements on the #OriginsofCOVID

If everyone posted what they thought about the origins, we would realize it's not that polarizing.
I suspect most scientists - especially the majority who have not dedicated weeks and months to looking into as many pieces of evidence (sometimes stretching all the way back to the first SARS epidemic) - would come up with:

I don't know. We should investigate.
This is the baseline I started with a year ago.

I had not read @TheLancet letter by Daszak. I had no idea about the politics of the origins.

I thought my well-meaning colleagues were paranoid when they said having text about lab origins in a preprint would be dangerous.
This is what we said in May last year. It was not conspiratorial. We laid out the top 3 scenarios that I continue to believe are each plausible and cannot be dismissed without a proper, credible, independent, transparent, accountable investigation. biorxiv.org/content/10.110…
If any scientist wants to rule out natural origins today, in the terrible absence of any data or evidence, I would fight just as hard as I'm fighting now to get a proper investigation going into these scenarios of natural spillover.

(Probably not for #PopsicleOrigins though...)
As I told @razibkhan back in Dec 2020, I don't think I would undo what I have done in the past year. But here are some serious learning moments I want to convey to other scientists (especially early career) thinking about looking into #originsofcovid ... unsupervisedlearning.libsyn.com/alina-chan-on-…
Number 1. This **** is going to be political no matter what you do.

As one brilliant person put it, the stakes could not be higher.

You're going to go in thinking you have enough patience.

You don't.
You could try and stick to the facts as much as possible. Try and be as empathetic as possible.

But with all the mud slinging politics and the I-can't-believe-this-BS "peer" reviews you receive along the way, I think even a saint would crumble.
Number 2. You're going to experience a series of unanticipated situations.

Not a week goes by without some scientist calling you a conspiracist with an agenda.

But at the same time, experts are calling and emailing you every hour to get your analysis and take credit for it.
I am very pleased to be helpful to experts on this matter, but at the same time there are people talking to me, asking me to explain EVERYTHING, and then putting out their shows and articles (maybe even books and documentaries) without crediting my intellectual contributions.
While every other day, I have to battle off Chinese sponsored anonymous twitterers, scientists who think I'm a QAnon-level misinformation spreader, and occasionally people (scientists included) emailing my employer to get me fired.

This is not sustainable. I'm close to quitting.
Clarification: Not quitting my job because I super love it.

Quitting this origins BS where experts are literally investigating work that they funded/were a part of.

At first, I just thought the scientific community needed a bit of nudging.

Now I realize it's 99.99% bystanders.
The last thing, which I felt strongly after reading the @undarkmag article... is that scientists (especially the ones in relevant fields) are not going to be the people solving the origins of COVID-19 or even helping to prevent a future lab leak pandemic. undark.org/2021/03/17/lab…
There are many things wrong with science, or rather, scientific practices. And the pandemic has shown us how these shortcomings can be exploited to manipulate public perception and "scientific consensus."

This is not a "the experts are wrong" situation.

The experts are human.
Even if we never find the origins of COVID, can we at least fix these problems?

Open peer review #OpenScience

Establish public forums on pathogen research & other key research, involve non-scientists and policymakers.

Invest in #ScienceCommunication and #ScientificLiteracy
There is no one occupation of people who can be self-governing and self-auditing.

There needs to be accountability even amongst people whose jobs are to seek and investigate the truth.
I had held on to hope but just don't see this scenario happening any more:

Where a group of top international scientists band together and say, scr*w the politics, we're going to investigate lab origins seriously & look at all available data (so much of it is outside of China).

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More from @Ayjchan

16 Mar
Dear @NPR @FoodieScience it's become quite clear to me that you need help with researching what questions to ask the WHO-China team and SARS experts. Please reach out. I can also recommend top experts of indisputable renown that you should be interviewing.
npr.org/sections/goats…
Linfa Wang says there were SARS2-positive samples in the live animal section - were these the environmental samples that have already been analyzed, suggesting introduction by an infected human into the Huanan seafood market, rather than any on-site animal to human spillover?
Read 12 tweets
15 Mar
Because we have no idea when SARS2 / COVID-19 actually emerged in Wuhan, and 2019 case numbers may have been drastically under-reported, it's worthwhile to revisit reports of suspected COVID-19 cases in 2019 that were super strange in early 2020: leparisien.fr/international/…
In Wuhan the "Military World Games - nearly 10,000 athletes representing 100 nations - took place from October 18 to 27" 2019.

Spokesperson for "Chinese Foreign Ministry, hinted on Twitter on March 12 that the coronavirus may have been introduced by the US delegation"
Back in early 2020, when I read about this, I thought it was completely out-there - that it was just people who had seasonal flu or common cold and were alarmed by reports of the novel COVID-19 coronavirus.

But now the covid-19 timeline has extended back to possibly Sep 2019...
Read 12 tweets
14 Mar
We don't know when the WHO-China report on the origins of covid-19 will drop. Maybe in the next week. Maybe the week after. Maybe next month.

Their interim report was supposed to have been released in February.

These are basics journalists should ask...
Who is on the team?
"The joint international team comprise 17 Chinese experts and 17 international experts from ten other countries."

Who are these experts and do they have reasonably perceived conflicts of interests?
who.int/publications/m…
What data did the team have access to?

Based on this access, which origins hypotheses could they have even possibly have studied properly?

We know they were not even able to access the original, full data on early cases or suspected early cases.
Read 6 tweets
14 Mar
In anticipation of some excellent articles on the origins of covid-19 coming out next week, I think it would be useful to cover a few areas of confusion relating to what experts mean by the "origins" of a virus, what counts as lab origins, and what counts as Gain-of-Function.
Over the past months, we've seen reports of SARS2-like viruses discovered across a wide geographic area from Thailand to Japan. Still the closest relatives to SARS2 are viruses from Yunnan, China.

What does this tell us about the origins of SARS2 and how it emerged in Wuhan?
Frankly, it tells us what we've known since the beginning.

That the ancestral origins of SARS2, like other SARS viruses, is in 🦇 and that the hotspot is in Yunnan, China or proximal to Yunnan.

Some experts are very keen to sample SE Asia just across the border from Yunnan...
Read 27 tweets
13 Mar
I think that it is important for scientists & public stakeholders across diverse fields of training to convene and discuss the range of pathogen research occurring worldwide as we tweet.

I wouldn't raise this except in the context of a pandemic that has shut the world down...
We may not know for years or even decades, for sure, how COVID-19 / SARS-CoV-2 came to be.

In this situation, we just have to prepare for each of the plausible origin scenarios - natural spillover, lab leak, and unfortunately, for some subset of 🌏, cold chain #PopsicleOrigins
Before we set up another forum or advisory board (which mustn't just be scientists this time) to discuss how to evaluate the risks of pathogen research, it's important to look back on the past few years of this type of debate among scientists on Gain of Function (GOF) research.
Read 29 tweets
13 Mar
Here is the layperson-appropriate coverage of the Mojiang mine and its relevance to COVID-19’s origins. Thanks! ⁦@TheSeeker268⁩ ⁦@thetimesplay.acast.com/s/storiesofour…
Three major issues by a scientist’s review.

One, most of WIV’s SARS work had been done at BSL2/3 not BSL4. It doesn’t matter what their BSL4 looks like. The work was done at a level where undergrads can be touching their faces and personal belongings with contaminated gloves.
Two, we keep hearing this expert stance that there’s no evidence for lab leak.

Guess what. There’s also no evidence for a natural spillover.

If a lab accident is a baseless conspiracy, then so is an accidental natural spillover.
Read 12 tweets

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