Thank you everyone for taking the time to vote on my first poll. Of course the mighty macrophage wins! It is probably the coolest cell type I’ve encountered, and even after being obsessed with it for 7 years, I still don’t know it well enough!
Macrophages are white blood cells, they circulate in our blood and reside in pretty much all our organs. They are omnipresent and have adapted themselves too well to each environment. The blood macrophage looks completely different from those in the brain or the bone.
The first thing I learnt about them was that they are phagocytes. They can eat an insane amount of stuff! Phagocytosis literally means ‘to eat cells’, so our first thought is this is the macrophage’s destiny!
When the particles are extremely small (nanometers – the size of our DNA and proteins), the cells take in a sample of the fluid surrounding the particles as well (called pinocytosis), to know exactly what’s going on in its surroundings.
The smallest particles they can eat are nanometers in size, this is the size of some viruses like the yellow fever virus. The largest particles they can eat are their own size – 20 micrometers! That's like the difference between eating one burger and 10,000 burgers at once!
So they can gobble up pretty much all the microorganisms that are a threat, and oh they do! They also eat dying cells that send an ‘eat me’ signal, or cells infected with viruses/bacteria or cancer cells! These cells are coated with proteins that tell the macrophage to attack!
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I'm also in awe watching people handling the pandemic their own ways. Some are working midnights and weekends to manage kids at home, some are taking a step back and taking a break, some are learning new things and some are even changing careers.
One thing in common is ALL of us are struggling somehow. I've seen comments on how parents are struggling more than single people and I understand it's easy to come to those conclusions (being a parent myself) but everyone's struggles are their own.
I am not diminishing the horrors our healthcare workers and countless others are facing, we owe everything to them, but this is such a unique situation that even the person in the cushiest position with no responsibilities has their ground state changed and is coping.
It's such a unique opportunity to talk to over 90k of you who are interested in science and scientists. It's such a broad term isn't it? I spent over 15 years actively studying science but I almost cringe to say I'm a scientist now because it's been a year since I left academia.
The idea that academia is the be all and end all of a scientist is so drilled into our heads that leaving the system feels like a failure. I know the system is rigged against a lot of people who leave, but some of us leave because our passions lie somewhere else.
There are a lot of reasons people aren't recognized as scientists, academics who aren't in STEMM fields like the social sciences & environmental sciences, people who move to industry, heck people who give up science to be stay-at-home moms or dads. WE WILL ALWAYS BE SCIENTISTS.
Hi all,
I’m Rukmani and I am thrilled to curate for Real Scientists this week! I am a freelance science writer and editor with a background of over 10 years in bioengineering focused on different aspects of wound healing.
Up until last year I was a full-time hands-on postdoc and I’ve been so privileged to work on some cool branches of bioengineering (that I can’t wait to share with you all)!
I left the lab to venture into science communication because this is where I felt most natural - it’s still early to call it my true calling because I’ve not done it long enough, but if this past year has taught me anything, it is to go with the flow!
I often compare early careers in academia to professional sports, specifically minor league baseball. They’ll take a look at the schools you played at, your overall stats, maybe they’ve seen you give a talk or two.
If you had a good year or two, maybe people talk about you. Just had a bad year? Pass.
A handful of people will get the “golden ticket,” a stable, long-term arrangement. Most will get a string of 2-year deals, shuttle to-fro between “big leagues” and “minors” before leaving.
Last day curating this account! Thank you for your attention and wonderful feedback so far!
I’m planning to close out with this thread about my journey through academia/astrophysics and into tech/DS, then another about some observations between academia and tech industry.
Prologue:
I did "well" in courses in undergrad. I took ~7 graduate level physics courses, graduated with high honors, worked in a lab.
But I was NOT prepared for academia.
Chapter 1: grad school (1st attempt)
The first PhD program I went to was… a mess. It was about 80-90% men, which is typical of physics programs, and most of the men had a drinking problem. (In retrospect, me, too.)
Most of the US legal framework regulating financial investments—having registered representatives for selling securities, rules around what they can and can’t promise, disclaimers for ads and prospectuses—came about as a result of the 1929 market crash.
I believe that the repeated mass-scale harm caused by Big Tech algorithms is ample proof that we need oversight and penalties—especially for automated decision making systems.