I do not think I am, in any way, in the position to give suggestions to others in this new medium, cryptoart.
No one is.
However, I can share my ideas. Everything is personal, but, I will try to provide as many points as possible for an approach of success..
First of all, I see this as a new medium rather than a new marketplace. This shapes a lot of things in my work(s).
A new medium means new ways of communication to begin with.
In other words, yes, tokenizing old works makes a lot of sense from a blockchain/history point of view, which I sometimes do, and will keep doing - but also, designing* something new for this brand new medium that explores new paths, is vitally important.
From a creator point of view, anything can feed creation. A moment of inspiration. A piece of music. A smell. Anything that triggers the chain reaction of the mind, an impulse, a spark of insanity, a touch.
After all, we consume what consumes us.
From a designer point of view, problems feed creation. They expect to be seen, giggle every time we take a step into their riddles, and finally, a resolution. A design. An answer. Simple. Beautiful.