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Prof Peter Hotez MD PhD Profile picture
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14 Apr, 5 tweets, 2 min read
Many thanks ⁦@KatyOnMSNBC⁩ ⁦@KatyTurNBC⁩ for hosting me, as I reported on the rationale for J&J pause, and using this period to see if additional cases of cerebral thromboses have occurred, whether it’s an issue with all adenovirus vectored vaccines: JnJ AZOx Sputnik
Some additional points...
First, possibly 10-15 years ago no one in US would have questioned a pause, but now we have an aggressive antivaccine movement in US + weaponized health communication from Russia discrediting Western vaccines. US Govt has refused to launch a counteroffensive and created a monster
Second, unlike the US or Europe which has alternatives in the mRNA vaccines, African and Latin American countries have no such option. They need to find a path to continue the adenovirus vectored vaccines and our FDA and CDC must help them. In addition....
Third, in collaboration with @biological_e in India 🇮🇳 our @TexasChildrens Vaccine Center has developed a low cost recombinant protein vaccine for global health, 1.2 billion doses. We need to accelerate this for Africa and Latin America

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More from @PeterHotez

Prof Peter Hotez MD PhD Profile picture
16 Apr
Apologies for disappointing you, my inbox is flooded with medical advice queries: I could answer them 24/7 and still not get to all of them. Honestly I’m not sure what to do, literally dozens every day, and each one requires thought, most provide incomplete information.
Instead I try to go on as many grand round lectures, podcasts, radio call in shows as I can. Usually 4-5 per day, and I still have the lab meetings, and cable news interviews. Most days I’m up at 4:30 AM, asleep by 10:30 PM, a couple of extra hrs on weekends. Like this for 16 mos
In between, hundreds of emails to answer or triage. Many wonderful expressions of kindness, which mean a lot to me. But equal filled with hate and evil, especially from Q gang. Those are especially demoralizing, and they set me back. Sometimes I pause until my darkness lifts, or
Read 4 tweets
Prof Peter Hotez MD PhD Profile picture
14 Apr
My best guess is that the recent heightened antiscience antivaccine aggression targeting Me, Tony, Vivek and deliberate twisting we see nightly on Fox News programming has little to do with any particular anchor. It’s an executive decision from higher ups thedailybeast.com/tucker-carlson…
Why the Murdoch gang wishes to go in this direction and work against American interests is unclear to me, I could guess on the basis of ratings competition, need to rebrand, create new think-tank identity around discredited ideas or pseudoscience, caving to foreign influence?
All conjecture until someone internally comes forward
Read 5 tweets
Prof Peter Hotez MD PhD Profile picture
13 Apr
Many thanks ⁦@tomkeene⁩ ⁦@FerroTV⁩ ⁦@lisaabramowicz1⁩ for hosting me on ⁦@BloombergTV⁩ discussing events with JnJ vaccine why it’s on hold and the possible mechanisms of blood clots from adenovirus vectored vaccines, JnJ, AZOx, we don’t know about Russian
Based on AZOX another adenovirus vaccine, this class of replication deficient viral vectored vaccines can stimulate anti PF4 antibodies. PF4 found in platelet granules. This activated platelets, causes platelets consumption, and then thrombotic thrombocytopenia.
Rates about 1 per 100,000 to 200,000 for AZOx, 1 per million for JnJ, we don’t know about Russian adenovirus vaccine since it bypasses stringent regulatory authorities
Read 5 tweets
Prof Peter Hotez MD PhD Profile picture
12 Apr
This conservative strawman is a bit ridiculous. Here's the way it is:
1) If we can fully vaccinate the US population we will return to something very close to normalcy by summer..
2) by that time restaurants, concerts, ball games, likely without masks...
Read 7 tweets
Prof Peter Hotez MD PhD Profile picture
10 Apr
Tonight on ⁦@PamelaBrownCNN⁩ I explained that emerging data finds that all of the US COVID19 vaccines work well vs the B.1.1.7 variant now accelerating across the country. The other variants having an additional E484K mutation, not so much, but..
But these other variants of concern for now are of secondary importance to B.1.1.7 in the US. Later the E484K VOCs from South Africa or Brazil may become an issue in the US and for that except one-time boosters later this year or in 2022.
In the meantime all attention must focus on B.1.1.7 now making young people sick, that’s why expanded EUA for adolescents 12-15 yo is important. Last time VRBPAC was not unanimous about the 16 and 17 year olds, we’ll see how they feel about adolescents
Read 4 tweets
Prof Peter Hotez MD PhD Profile picture
10 Apr
1/4: Interesting observation: New Hampshire leads the nation in COVID19 immunizations, almost one-half of the population has received a single dose of vaccine, yet the cases continue to rise, currently one of the most affected areas of the US. Some hypotheses why:
2/4: is it because most of the jabs are in older population, so that transmission still rampant among younger groups? Interesting that deaths down but hospitalizations still significant
3/4 Or a single dose dose doesn’t do much in terms of halting transmission, that requires full immunization with 2 doses?
Read 5 tweets

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