A high viral dose exposure, a bad mutant variant, or an immune system compromised by prior illness or chemotherapy — are 3 potential reasons why COVID reinfection or post-vaccine infection may occur.
Lowering viral dose exposure can be achieved by masks, distancing, ventilation. I think it's a good idea to follow these measures until the pandemic is under control in your country, even if you have had prior COVID and are vaccinated. Helps you. And helps reduce spread to others
Immune system thats compromised by prior illness or chemotherapy can be helped by ongoing research on vaccine boosters. As well as improved treatments. But note that no matter how immunosuppressed, whatever protection we get from vaccines is definitely better than nothing.
The rise of bad mutant variants can only be addressed if we look at controlling COVID from a global perspective. COVID raging in any part of the world has consequences for everywhere else. COVID doesn't know geography or politics. So we must make sure the world is vaccinated.
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COVID vaccine & Blood clots update: The European Medicines Agency @EMA_News has concluded that unusual blood clots with J&J vaccine are a very rare side effect.
COVID mortality by age group & implications for Astra Zeneca, J&J vaccines:
1/ The chances of dying if you get COVID infection (IFR) is ~0.5% (USA). Varies by country.
2/ In EVERY COUNTRY risk varies dramatically by age.
Age 50-64-->10 times higher risk of death than 30-39. 👇
3/ The estimated risk of dying from COVID infection (infection fatality rate; IFR) is:
~1 in 400 for age 45-54,
~1 in 125 for age 55-64, and
~1 in 40 for age 65-74. link.springer.com/content/pdf/10…
4/ The numbers in the table are for all COVID infections, with and without symptoms. The risk of dying from COVID is 3-4 times higher if you have confirmed Symptomatic COVID. This is not the flu.
1/The COVID virus doesn't know political borders or geography.
Countries which controlled the pandemic from the outset made 1) the politically & economically hard decision of closing borders except through quarantined entry, and 2) test/trace/isolate within.
2/ Depending on how many cases were already inside, some countries had to also implement universal masking and distancing. Countries which managed to seal borders before significant amount of cases got inside the country could get away with limited masks and distancing measures.
3/ Countries where COVID could not be controlled in time unfortunately ended up with large numbers of affected people. Masks & distancing are needed to limit spread & save lives until a definitive solution could be implemented. We have a highly promising solution now: Vaccines.
61 year old man was diagnosed with Hodgkin Lymphoma. He then developed COVID. Only got supportive care. No steroids or immunotherapy. 4 months later, cancer had mostly resolved (left image vs right) 🪢
1) Hodgkin Lymphoma is unique among cancers in that what you see as big lumps of tumor are not cancer cells: Bulk of tumor mass is just normal reactive lymphocytes with small amounts of cancer (Reed Sternberg) cells mixed in. (Owl like cells)
So after COVID the reactive cells may disappear due to the severe viral infection, making it look like the cancer has gone into remission. But maybe only the normal reactive cells have disappeared. Time will tell if the true Hodgkin cancer cells are still there and will come back