I was wrong in my assessment. Two months ago, I felt India had somehow miraculously escaped the devastation caused by the pandemic in so many countries. COVID has humbled me, again.
No easy solutions for India except masks, distancing, and rapid vaccination. It is a crisis.
I still hope that one of the main points of my earlier thread that preexisting immunity (in addition to lower age and less obesity) will keep the mortality rate significantly lower is correct.
But with such a huge population, even a tiny mortality rate is millions of lives.
We thought 40% seroprevalence meant inching to herd immunity. No.
The 1.3 billion population means that 750 million people are still potentially susceptible and don't have immunity against COVID.
What happened in India has implications for countries that controlled COVID well like Australia, New Zealand, China, S.Korea, et al. If you relax precautions before herd immunity through vaccination is achieved, the population remains susceptible. If COVID enters, it devastates.
What happened in India has implications for Africa. We cannot assume anything. We must help vaccination in Africa on a massive scale.
What happens in India has implications for everyone in the world because with so many infections, numerous mutants arise. We have to help India get vaccinated. Fast. Please break any barriers for resources and help them achieve this goal. It helps everyone of us.
Since November people in India went about near normal lives as if the pandemic was over. Large crowds & no masks were common. There was a false sense of security. Even now people seem fatigued, and adherence to masks/distancing is low. Many places are resorting again to lockdowns
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Updated Risk of vaccine related cerebral venous sinus (or splanchnic vein) thrombosis associated with low platelets
Astra Zeneca
1 in 100,000 (EU)
1 in 250,000 (UK)
J&J
1 in 500,000 overall.
1 in 150,000 for women age 18-49.
No risk seen with Moderna or Pfizer vaccines.
The risks are extremely low. Awaiting CDC panel recommendations on J&J pause.
The pause was justified. To determine the numerator & the denominator. CDC panel has voted today to resume vaccinations with the J&J vaccine. statnews.com/2021/04/23/cdc…
Important: The rate of blood clots with low platelets reported with Pfizer and Moderna are LOWER than expected for general population. These vaccines are safe and don't carry excess risk.
A high viral dose exposure, a bad mutant variant, or an immune system compromised by prior illness or chemotherapy — are 3 potential reasons why COVID reinfection or post-vaccine infection may occur.
Lowering viral dose exposure can be achieved by masks, distancing, ventilation. I think it's a good idea to follow these measures until the pandemic is under control in your country, even if you have had prior COVID and are vaccinated. Helps you. And helps reduce spread to others
Immune system thats compromised by prior illness or chemotherapy can be helped by ongoing research on vaccine boosters. As well as improved treatments. But note that no matter how immunosuppressed, whatever protection we get from vaccines is definitely better than nothing.
COVID vaccine & Blood clots update: The European Medicines Agency @EMA_News has concluded that unusual blood clots with J&J vaccine are a very rare side effect.