Revealed: Why Britain’s regulator missed the link between the AstraZeneca jab and rare blood clots telegraph.co.uk/global-health/…
2/ We confirmed the first three cases of CVST+H happened in Jan and Feb. Two life-changing events and one death. The first Yellow Card came in, say the MHRA, on 8 Feb - the day the vax launched in Europe. Why were these and other early signals missed?
3/ We identified three reasons. First, the "sensitivity" of the algorithms/processes used by MHRA were lower than in parts of Europe. We tracked against background rates, while others turned the sensitivity dial up to 11...
1/5 I find the debate over aerosol transmission very odd. It's perfectly clear respiratory viruses spread that way in part at least, and has been for years. It raises some important questions for Western science ...
2/ First, why the reluctance to accept what is so clearly evidenced? My guess is that like so much necessary but avoided pandemic planning, it's all about resources and long established (but incorrect) professional group think ...
3/ If you accept respiratory viruses can spread via aerosols, you need to rethink the design of countless systems, buildings and public health protocols. It's a huge job which disrupts everything. It's therefore one we would prefer to avoid, or "park" in the language of PHE...
1/4 Tony Blair intervened to save the Windsors after Diana's death. Boris (for it is he) must try to do the same today. The family's fragile legitimately rests on it representing the *entire* nation and the skin colour bile utterly undermines that...
2/ The deep outrage and offence it has, and will continue, to cause should not be underestimated. There will be lame attempts to pass it off as one Phil's bad 'jokes' but it won't wash... telegraph.co.uk/news/2021/03/0…
3/ Meghan offered this get out of jail card: "There's the family, and then there's the people that are running the institution, those are two separate things and it's important to be able to compartmentalise that because the Queen, for example, has always been wonderful to me."
1/5: Medical triage (rationing) in a crisis is a difficult issue but it needs to be confronted directly to prevent things getting much worse. We are now at alert "Level 5", meaning there is a *material risk* of NHS services being overrun, so I looked at it for today's paper...
2/ First, the news story. In the absence of national guidelines (more on that shortly), clinicians in Bath have drafted and circulated a detailed protocol for debate among doctors. The story is free to read here: telegraph.co.uk/global-health/…
3/ A news story can never do justice to such a complex subject but can spark debate. You can read the full draft protocol and accompanying background here. Note, the authors wrote it when deaths were low to encourage calm debate ... jme.bmj.com/content/medeth…
1/4 What will PM say tonight? My guess is it will be a March-style national lockdown, with many schools closed. Here is some of the data driving the decision making. Note, school closures push the London/SE peak, taking pressure off a stressed NHS #COVID19
2/4 These charts show impact by region in absence of widespread vaccination. Deaths in 6mth to July worse than last year - start in London and SE and spread across country. The reason: new variant is breaching current measures and infecting many more people...
3/4 Here is how it looks with vax rollout. Still worse than 1st wave unless we can get to 2m shots a week by January 1 - 4 days ago. We are currently at about 300,000 shots a week
1/4 Quick thread on vaccine rollout globally. Key message: supply is super tight and will remain so for some time yet. Global coordination urgently needed... Israel ahead in % population but it is a small nation...
2/4 In terms of doses delivered - a indication of access to supply - China and US miles ahead and neck and neck. Expect India to race up in next few weeks. Remember China has been administering vax since the summer...
3/4 Doses administered gives an indication of a country's ability to scale up. Here US and Israel stand out, though scale of countries is vastly different....