1/ India is setting global records for COVID cases—and the numbers are massively undercounted. Hospitals are full. Patients have died as hospitals have run out of oxygen. Cremations are taking place in parking lots and parks.
2/ Colleagues and I are putting together guides on how to care for COVID at home (more Indian language translations to come) because the situation is so dire.
3/ And it’s not just India that’s suffering.
Cases are on the rise in the region.
There’s still time to act: masking, social distancing, ventilation, testing, and vaccination.
4/ Indian PM Modi must do better. You can’t vaccinate your way out of a surge. Only mitigation measures take effect immediately. Modi must reinstitute masking & social distancing, & this time do so humanely, providing people the social supports they need to weather this crisis.
5/ The Biden administration must also do better. It announced plans to share up to 60M doses of the AstraZeneca vaccine with other countries, once cleared as safe by the FDA.
6/ The AZ vaccine is a 2-dose vaccine, so 60M doses is equal to 30M people vaccinated. India has a population of ~1.4B, so this is just enough to vaccinate 2% of its population.

Low- and middle-income countries will need 8B doses of vaccine to get to 80% vaccination coverage.
7/ Plus USG donations won’t happen right away. At best, 10M doses might be released in the coming weeks (i.e. 5M people vaccinated).
8/ This weekend, the U.S. lifted obstacles to the export of raw materials to India for vaccine manufacturing.

Serum Institute in India is the world’s BIGGEST vaccine manufacturer, but they can’t make vaccine out of thin air.
9/ We should help ramp up the production of raw materials for the entire world.
10/ The U.S. and others are hoarding COVID vaccine. We have so much vaccine supply that we don’t know what to do with it. American demand for vaccines is plateauing.

Other high-income countries are hoarding vaccine, too:
healthpolicy.duke.edu/sites/default/…
11/ The pandemic has shown the dangers of relying on the pharma industry & wealthy nations for their vaccine supply. It’s not enough to donate our excess supply. We’ve got to help massively scale up production.
12/ We need to share intellectual property and manufacturing know-how, supply raw materials, help build local manufacturing capacity, and build local manufacturing expertise so that every country can be self-reliant in a pandemic.
13/ Meanwhile, vaccine manufacturers have insisted on sweeping liability protections that make it difficult for poorer countries, unable to guarantee those protections, access. These companies want to protect their profits over human lives.
nytimes.com/2021/04/24/opi…
14/ USG should leverage its patents on Spike protein stabilization tech (used in NIH-Moderna, Pfizer, J&J vaccines) to nudge pharma to license technology & manufacturing know-how to contract manufacturing orgs & to not hold countries hostage with ridiculous indemnity clauses.

• • •

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More from @celinegounder

25 Apr
1/ I am so relieved to hear this news:

The U.S. has identified sources of specific raw material urgently required for Indian manufacture of the Covishield vaccine that will immediately be made available for India.

whitehouse.gov/briefing-room/…
2/ To help treat COVID patients and protect front-line health workers in India, the United States has identified supplies of therapeutics, rapid diagnostic test kits, ventilators, and PPE that will immediately be made available for India.
3/ The U.S. is pursuing options to provide oxygen generation and related supplies on an urgent basis.
Read 6 tweets
20 Apr
1/ Just released:
Survey data from @FrankLuntz, @BrianCCastrucci, and the @deBeaumontFndtn on J&J vaccine pause.

Here’s a quick summary according to partisan affiliation.

Biden voters slightly more likely and Trump voters slightly less likely to get COVID vaccine.
2/ Biden voters are evenly split and Trump voters are slightly less concerned about getting a blood clot from a COVID vaccine.
3/ Almost everyone who's already been vaccinated would do it again:
Read 15 tweets
18 Apr
1/ "...the #BLM movement & ... COVID... are stark reminders of the pernicious effects of systemic racism..."
science.sciencemag.org/content/372/65…
by @ShirleyTilghman (one of my molecular biology profs at @Princeton), my dear friend @KafuiDzirasa, former @NIH Director Harold Varmus & more.
2/ "The lack of diversity in the scientific and health professions—a longstanding manifestation of racism—can no longer be ignored, excused, or attributed to uncontrollable factors."
3/
Read 18 tweets
15 Apr
1/ Interested in learning more about VACCINE CONFIDENCE, what some call VACCINE HESITANCY? Have a listen:
- EPIDEMIC.fm S1E64: concerns about vaccines are as old as vaccines themselves, dating back to the late 1800s and smallpox. justhumanproductions.org/podcasts/epide…
2/ Why are young moms targeted by the anti-vaxx movement? Hear form a mom who went from anti-vaxxer to vaccine advocate.
- EPIDEMIC.fm S1E65: justhumanproductions.org/podcasts/s1e65…
3/ Get a fuller picture of the African American experience with vaccines and public health and why we need to prove ourselves trustworthy to build trust in vaccines.
- EPIDEMIC.fm S1E68: justhumanproductions.org/podcasts/s1e68…
Read 6 tweets
15 Apr
1/ Apologies for not posting this sooner. I've been tied up juggling multiple jobs (Bellevue + media + congressional testimony + other), but I think it's important to get this out there now. I could have last night, but...
2/ The Food and Drug Administration and Centers for Disease Control and Prevention called for a pause on use of the J&J vaccine in this country. Six cases of blood clots have been reported among a million women between the ages of 18 and 48 who have received the vaccine.
3/ To put this in context, women who are not taking birth control pills have a 1 to 5 in 10,000 per year risk of getting a blood clot. This risk increases by more than 4x during and immediately after pregnancy.
Read 35 tweets
14 Apr
1/ I have counseled patients on:
- why they need to keep taking their tuberculosis antibiotics for months
- why they need to get tested for HIV or sexually transmitted infections
- why they should take pre-exposure prophylaxis for HIV or antiretroviral therapy
2/ I have worked throughout sub-Saharan Africa and spoken with religious leaders, teachers, community health workers, youth, journalists, activists, and politicians.

e.g. why didn't Guineans & other West Africans think Ebola wasn't real? Because they didn't trust the government.
3/ Analytic methods only take you so far. The math we use in epidemiology and economics, for example, is essentially the same. What's different is an understanding of the context, and that comes with experience on the ground, working with people.
Read 4 tweets

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