Lazarus Long Profile picture
Apr 30, 2021 12 tweets 5 min read Read on X
Always a great study when tweeted out by Dr. Noakes - let's dive in.

✅2 cases of transmission from bus drivers to passengers up to more than 9 feet/ 3 meters.
✅Genomic confirmation
✅Airflow traced - please see Dr. Noakes original thread for commentary on the method used.
Limitations:
📌Facemask compliance unsure
📌Fomite possible. Not likely
📌Community transmission possible - but not likely
Two trips and two separate van drivers involved.

Both trips - windows closed, ventilation NOT on recirculate, heaters on medium fan.

First trip - 4 patients on 2-hour trips to and from the hospital on December 2, 2020. Driver tested +positive on December 3, 2020.

Van below.
Driver had a high viral burden: 15.9

Driver and all passengers wore cloth facemasks and only interacted during boarding and transportation.
Second trip - The second driver transported 3 patients on the same 2-hour trip in the same van on
January 23, 2021, the day his symptoms began.

Van below.
Driver viral load was high - 24.

Driver was not in a mask, but the passengers were.
What everyone is most interested in - airflow tracing.

Heater on? Smoke released from the driver seat at headrest height rose and flowed toward the back of the van.

When heater and fans were off, no "microspheres" were recovered from the seats or air.

Next tweet method...
I don't remember seeing this exact technique before in any of the studies I've read. Not saying it's not valid at all. Just haven't seen it.
Contact Tracing Method
Genomic Method.
Our take-aways?

👉 #CoVidIsAirborne.
👉 #BetterMasks are necessary.
👉 If you open diagonal windows, you can create an air curtain. Like in this case, passenger and the window directly behind the driver.

In this case, that last bullet point was not possible due to passenger
windows not being able to be opened.

H/T @linseymarr for the air curtain suggestion about 1 million pandemic years ago!

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More from @LazarusLong13

May 28
Ebola - it's not all about respiratory aerosols.

DYK that you, and me, and everybody are Pig Pen from Charlie Brown?

We shed our entire outer layer of skin every 2-4 weeks, about 500 million cells daily.

Your corneocytes (outermost cells) lift off of your body with the
gentlest of micro-air currents. Like a leaf picked up off the ground for the briefest of moments in fall.

They act like 12 micron aerosols in float time, but 25% of total skin flakes are sub 5 microns...and you know what that means. Deep deposition - or shallow as
sub 5 likes to also deposit in the nose.

It's funny...I embrace push-back in debate. Tightens up my game.

Imagine if those skin flakes now have Ebola on them?

Two studies show that Ebola literally oozes through the skin - both ways. In and out.

Not shown in vivo, but
Read 10 tweets
May 23
The WHO forbids contact tracers from masking or gloving up.

"Do not conduct home visits wearing personal protective equipment like masks, gloves, or
gowns."

It gets worse. Do not conduct home visits wearing personal protective equipment like masks, gloves, or  gowns.
They have a handy how to reduce risk of catching ebola at home.

It even has 5 masks listed on it.

But not for the other family members.

"7. If the patient has vomit, diarrhoea or bleeding, a mask or a dry towel wrapped around the face can be used to protect the nose and mouth Image
7. If the patient has vomit, diarrhoea or bleeding, a mask or a dry towel wrapped around the face can be used to protect the nose and mouth when touching the patient or items soiled with blood or body fluids. A waterproof gown, eye protection, gloves and rubber boots should also be worn in these circumstances.
Here are the 5 face masks. Image
Read 9 tweets
May 22
The "epidemiology" of Ebola tells us that it's not airborne. You've heard this over and over.

What drives it? The questions on the contact tracing form.

Quick 🧵. Image
COVID - the WHO and CDC said it wasn't airborne via aerosols, right?

The CDC said it was spread person to person via close contact - within about 6 feet.



And you remember it took FOREVER to get changed.

The contact tracing form was web.archive.org/web/2020032817…Image
Image
arranged around close contact. These are the questions driving the stats of how many and how are infected.



So, the CDC will only hear back what it's asking. This was the epidemiology of COVID - until it wasn't. web.archive.org/web/2020052514…Image
Read 16 tweets
May 20
Speaking of silly, can we agree that the WHO has Ebola experts?

Let's talk about PPE, and a bias towards "less PPE is better." Image
The WHO EBOLA IPC guidance:


Foreshadow on PPE

"...due to the desirability of an off-
the-face design, and not for protection from aerosols, respirators may be used instead of medical masks"who.int/publications/i…
If you can stay 3 feet away while screening? No medical mask needed. Image
Image
Read 12 tweets
May 10
Great article by @EmilyJoshu here.

Emily, there's another article in this that's even more shocking.

The aerosols from milking have long been discussed by many of us on X.

People like myself, @sri_srikrishna, @AbraarKaran have long advocated for comfortable aerosol
protective gear like PAPRs. But, have been ignored by the USDA who, of course, thought it was only contaminated milking gear like the claw.

But there is one more source of aerosols besides cow breath.

The wastewater. When you spray anything you generate huge amounts of Image
aerosols. And that farm wastewater, filled with milk dumped from being full of H5N1, gets reclaimed and reused.

Those milk and wastewater lagoons are on most dairy farms (my grandfather owned a dairy farm).

And there's something you should know.

Image
Read 15 tweets
May 7
Humanity's hubris vs the precautionary principle.

The virus, ANDV, will do what it will do. Pandemic? History tells us "NO." But history is in the past.

Let me show you what the studies tell us - and why I am livid that the WHO is insisting that surgical masks are ok.

🧵
Incubation time, or how long until symptoms show up?

The high risk time frame is 14–32 days. Not to put too fine a point on that, but that can mean a full month later

pmc.ncbi.nlm.nih.gov/articles/PMC32…

There have been some out to 8 weeks, but let's ignore those

gov.uk/guidance/andes… Image
Clinical features The most important complication of ANDV infection is HCPS, which is associated with a high mortality rate. Milder illness without significant cardio-respiratory compromise may also be seen. Illness usually develops 2 to 4 weeks following exposure, but incubation periods as early as 4 days and up to 8 weeks have been described.
But, what receptor does the ANDV attach to?

PCDH1 (protocadherin-1) is primarily expressed in the airway epithelium of the respiratory system, especially in the bronchial and nasal epithelial cells, and in pulmonary endothelial cells.

So, that means in the URT and the LRT.
Read 41 tweets

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