Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
@nihardesai7
May 8, 2021 • 9 tweets • 5 min read • Read on X
Scrolly
CELLS in Hemat 💪🏻

Sickle cell=Drepanocyte➡️SCD
Tear drop=Dacrocyte➡️MF
Spur cell=Acanthocyte➡️Liver ds
Burr cell=Echinocyte➡️Uremia/PK def
Target cell=Codocyte➡️Hb'pathies
Bite cell=eccentrocyte➡️G6PD def
Pencil cell=ovalocyte➡️IDA
Pincered cell➡️Band 3 def
Prickle cell➡️PK def
@HaryaxPathak @AlishaAkhani @pankti4299 @VedangDesai02 @shreya__kataria @HemOncFellows @hard_dil @nitsoccer @docsamdeshmukh @BloodAdvances #MedTwitter #hemetwitter
Sickle cells, not hard to identify.
Can't miss these isn't it ?
Tear drop cells a/w marrow fibrosis.
Acanthocyte/spur cells , irregularly spaced "spikes" !!
A/w liver disease, abetalipoproteinemia.
In contrast to the above image, note how the "spikes" are regularly spaced !!
These are ecchinocytes/burr cells a/w uremia.
Bull's eye. Hard to miss these target cells. Seen in thalassemia and other Hb'pathies and also with asplenia.
That took a BIG "bite" out of that !!!
G6Pd deficiency.
All images are from the @ASH_hematology image bank. A big thank you for existing 💪🏻🙏🏻

P.S. I am not a hemato-pathologist. Those guys are from a different planet. RESPECT 🙏🏻

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with 𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM

𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @nihardesai7

𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
Oct 4
Hey #MedTwitter 👋🏼

A bit about SMUDGE CELLS today!

Also called smear cells because they were initially thought to be artifacts of smear production!

Also called Gumpretch cells after Dr. Gumpretch who first described them in the 1800's

But there's more 👇🏼

#MedTwitterImage
Where do you see them?

Many conditions, but it is almost always seen in patients with Chronic Lymphocytic Leukemia (CLL) 👇🏼

#MedTwitterImage
Some patients have very few smudge cells while others have an abundance of these cells 🤷🏼

Why??

#MedTwitter
Read 9 tweets
𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
Sep 12
As a physician I'm sure you've seen patients with ITP!

Let's start by calling it IMMUNE thrombocytopenia instead of IDIOPATHIC thrombocytopenia.

The P stood for Purpura in the past. Not anymore!

T= Thrombocytopenia = <100,000 platelets

#MedTwitter
1/20
ITP comes in 2 flavours:

•PRIMARY
and
•SECONDARY

SECONDARY TO WHAT?
Long list of possible causes, autoimmune disease, HIV, HepC, drugs etc

#MedTwitter

2/20
If the thrombocytopenia lasts >12 months, the patient has chronic ITP 😭

This is unfortunately more common in adults; almost 75% develop chronic ITP 😭

#MedTwitter

3/20
Read 20 tweets
𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
Apr 4
Hey #MedStudentTwitter 👋🏼

Do you know what this image shows?

Obviously you do !!

If not, read this short thread 👇🏻

#MedTwitter

1/6 Image
Yeah, those are hemighost cells !

That's a hallmark of severe oxidative damage to red cells. Most often seen in G6PD deficient individuals!

I say most often because it can happen in patients with normal G6PD levels when the oxidative damage is severe 😭

#MedTwitter
2/6
You cannot see Heinz bodies in that image 😔 They will NOT be seen on Romanowsky stains !!!

The red cell will appear like an emptied out "ghost cell" when the hemoglobin denatures 😔 That's what you saw ☝🏼

👇🏻 Is a supravital stain showing Heinz bodies (blue dots)!

#MedTwitter Image
Read 6 tweets
𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
Feb 28
An easy way to remember serum protein electrophoresis for #MedstudentTwitter !

In myeloma, the thumb goes ⤴️ and the pinky finger goes ⤵️

To know more than this, follow along 👇🏼

#MedTwitter

1/16 Image
Now let's see what each spike represents!

α1 =α1 antitrypsin +others (small amount)

α1 antitrypsin (AT) is an ACUTE PHASE REACTANT, so it'll ⤴️in INFLAMMATION

Obviously, α1 is⤵️in α1 AT deficiency!

It's quite simple, isn't it?

Wait, why is α2 ⤴️ in acute inflammation🤔

2/16
Image
Image
To answer that, we need to know what α2 contains !

Since it's elevated in acute inflammation, it must be an inflammatory marker 🤷🏻‍♂️

Yes, it is 🙌🏻

α2 contains ceruloplasmin, haptoglobin and α2 macroglobulin, all acute phase reactants!

Now we know why we get 👇🏼 pattern !

3/16 Image
Read 16 tweets
𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
Aug 16, 2023
📢📢 𝐍𝐄𝐖 𝐓𝐇𝐑𝐄𝐀𝐃 🧵

This is for everyone who uses 𝙘𝙮𝙘𝙡𝙤𝙨𝙥𝙤𝙧𝙞𝙣𝙚, so I'm guessing a lot of people would read this short thread !

It's every transplanter's friend; kidney/🫀/ liver/ BMT 💪

Follow along to learn more 👇

1/20

#MedTwitter Image
Let's roll back time 🔙 to the 1960's 😍

@thebeatles, @pinkfloyd and @ledzeppelin were ruling the charts🤘

Those were good days as far as music was concerned 🎶

Not so good for transplants!

There weren't many immunosuppressive drugs available back then😭

#MedTwitter

2/20
Transplanter docs were using AZATHIOPRINE & CORTICOSTEROIDS to suppress the immune system 😳😮

These drugs weren't good enough 😭

•Azathioprine - cytopenia
•Steroids - Don't get me started !
•Methotrexate - cytopenia, mucositis

#MedTwitter

The transplanter docs wanted 👇🏻
Read 20 tweets
𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Profile picture
Jun 2, 2023
Hey #medicine residents !!

Time to talk about EOSINOPHILS today. Not as common a consult as thrombocytopenia and anemia but important nonetheless.

A short 🧵 to touch upon all things eosinophilia 👇🏻

#MedTwitter Image
Before we go any further, it's important to know this

🩸Eosinophil ≥ 500 is ABNORMAL

Eosinophil is a predominantly tissue dwelling cell so 🩸 eosinophil DON'T correlate with tissue damage 🤷‍♂️

We see a few patients with ⤴️⤴️Eos and no 🫀🫁 injury !!
Where do eosinophils come from?

Short answer: Bone Marrow

They are cells of the granulocytic lineage, siblings of neutrophils and basophils, children of the myeloblast (image👇🏻)

IL5 is the cytokine responsible for it's production, important to know because we have anti IL5 mAb Image
Read 24 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

Send Email!

:(