So finally I have an answer to what has happened to Novavax production in India, thanks to the difficulty getting raw materials out of the US. The news was worse than I expected.
There is says, Stan Erck of that firm, a "global raw material supply difficulty".
It was said that this move was to support the production of the AZ vaccine in India (Covisheild). Nothing was said about the Novavax line.
It seems pretty clear that the answer is no--the US did not send enough materials to fix the problems on that line.
According to Stan Erck, the @SerumInstIndia did not have enough supplies to keep both lines going at full capacity. It kept the AZ line going at maximum production, and the Novavax line at a smaller scale.
(That would support this article that suggests the Novavax line is running at 1/3 of capacity.)
The bottom line is that the firm has had to move its production forecasts back a *whole quarter*.
That vaccine is important for India, where people are dying at a rate of at least 3,500 a day, and for Covax.😡
More broadly it raises the question of how other new vaccine entrants (J&J, Curevac) are managing to obtain the ingredients they need to manufacture.
If we do not resolve these issues quickly how much this will dent the intention to produce 10-14bn doses? @Airfinity@rasbech
The US argues the DPA isn't *causing* these problems there are just shortages of these items.
But firms say the DPA slows down exports, causes compensatory overstocking by other companies, and it disrupts supply chains.
And it isn't fair.
The US has plenty of vaccine.
The Pfizer vaccine relies on supplies from 19 different countries. What if those 19 countries decided they needed their own DPA in perpetuity? How would that work?
Firms also say things are worse under the current administration, not better.
Oh, and I have also heard of an un-named firm that had active substance in Europe, shipped to the US, and then were unable to get it out again. 😞
They had to improvise and find a new supply chain...
The US needs to become part of the solution, and stop being part of the problem.
When it moves to donate vaccine or support the global supply chains, other countries will follow and lives will be saved as a result.
Deputy chief medical officer Van Tam says UK covid cases are as low as they are going to get. Here is a visual reminder of where Israel and UK are at currently with cases (ours are just over 2,000 a day).
The briefing can be seen here:
26.50 Van Tam says: solid data on the way vaccine can cut household transmission.
Breaking: Singapore proposing social distancing measures in the wake of evidence of some community spread. Warns more stringent measures might be necessary. #2019n_CoV
Minister says: First, we will advise all event organisers to cancel or defer non-essential large-scale events. For those who wish to proceed, we will want them to take all necessary precautions....#2019n_CoV
Second, all employers and individuals should implement regular temperature-taking. They should be done at least twice daily. #2019n_CoV
@JohnTuckerPhD @John_LaMattina “Put simply, drug-related payments to physicians seem to increase drug prescriptions, and higher payments seem to increase them more."
@JohnTuckerPhD @John_LaMattina “From 2014 to 2016, the doctors who received payments prescribed, on average, over 13,070 daily doses of opioids per year more than their unpaid colleagues”
Fantastic news. @DrMikeRyan from @WHO spoke this morning of significant progress in DRC, and expresses gratitude and hope that the world is getting on top of this virus.
Ebola is still transmitting but is now cornered in a smaller geographic area.
Lots of hard work getting to this point with Ebola. @DrMikeRyan says “I do think that vaccination has had a major impact on the dynamics of the epidemic”.
Another factor is the availability of treatment. Knowledge of the new treatments means that patients are much more likely to present themselves for care. If they do they are much more likely to survive too...