A thread on the snippets (paragraphs & quotes) from the book ‘Lifespan’ by David Sinclair @davidasinclair
‘The clock is ticking’
This thread will be updated as I read further & further.
‘The clock is ticking’
This thread will be updated as I read further & further.
1/ “Every death is violent.” ~ Holocaust documentary filmmaker Claude Lanzmann.
2/ That scene from the film ‘Dead Poets Society’
3/ And Nothing was ever the same again.
The author is talking about 50 extra years of Health-span being the norm.
The author is talking about 50 extra years of Health-span being the norm.
4/ 400crore years ago, we started with a 2 genes in a single cell with this mechanism👇 to survive, now we are at 21000 genes & 30Trillion cells.
5/ We are the great survivors.
6/ Car T-cell therapy explained: Expected to grow at 45%+ for the next 7 years 🚀
7/ Consuming products filled with antioxidants does no good. It’s a marketing gimmick.
8/ How the scientists will push back death.
9/ There are 2 types of information in our cells: Digital (Genome) & Analog (Epigenome)
Simpler explanation for Epigentics: explains how nuture (not nature) leads to changes in your DNA.
Simply, how 2 twins which have the same genes can have diametrically opposite lives.
Simply, how 2 twins which have the same genes can have diametrically opposite lives.
10/ Why people who exercise or fast seem younger: Hormesis.
11/ That’s what is humbling about nature: something like yeast that is used in brewing beer can also help cure cancer.
12/ Why Yeast? 😉
13/ epigenome’s design.
14/ Simplest explanation of the epigenome: its melodious.
15/ A caterpillar can’t transform to a human, but only into a butterfly: Why the genome is equally important.
16/ “Studies of identical twins place the genetic influences on longevity at between 10 and 25 percent which by any estimation is surprisingly low.”
Our DNA is not our destiny.
Our DNA is not our destiny.
17/ From learning from yeast to learning from trees. I am sensing a pattern here.
18/ Real Life terminators.
19/ Aging is a disease.
20/ This is what being old feels like physically.
21/ We are living longer, but at what cost.
22/ Cigarette smoking increases chances of developing lung cancer by 5x. Here’s how it works 👇
23/ “Though smoking increases the risk of getting cancer by fivefold, being 50 years old increases your cancer risk hundred fold. By the age of 70, it’s a thousand fold.
Not just cancer, valid for heart disease. And Diabetes. And Dementia. The list goes on & on.”
Not just cancer, valid for heart disease. And Diabetes. And Dementia. The list goes on & on.”
24/ It’s that simple.
25/ The 1st & most probably the last genuine Self Help guy.
27/ Your diet probably needs to look a lot like a rabbit’s lunch than a lion’s dinner.
28/ Something in which protein shake drinkers be interested in.
29/ Wear one less sweater to live longer.
30/ Once you understand how cells actually work, they are the most amazing things.
31/ The possibilities with Gene Therapy 🧬 are 🤯
32/ ‘Precision medicine’ is catching up.
Not just what works for most people most of the time.
Not just what works for most people most of the time.
33/ The power of precision medicine & why do we need it.
34/‘It won’t be long before prescribing a drug without first knowing a patient’s genome will seem medieval.’
Enter Pharmocoepigenetics: We all don’t respond to medicines in the same way.
Enter Pharmocoepigenetics: We all don’t respond to medicines in the same way.
35/ The book predicted the current Pandemic.
36/ “Epidemiologists say a fast moving airborne pathogen will kill more than 30 million people in less than a year and they say that there is a reasonable probability that the world will experience such an outbreak in the next 10-15 years.” ~ Bill Gates in 2017.
37/ Be careful what you wish for.
38/ Even Nobel Laureates & Billionaires can underestimate compounding. The thing that differentiates us & them is that they are quick to change lanes.
39/ Reminds me of Anton Ego’s speech in the Pixar movie ‘Ratatouille’:
40/ Start working on getting rich if you want to live longer.
41/ All the age related advances in the next decades will be expensive.
42/ This will happen when we face a population explosion 🚀
43/ “In 1800, the global literacy rate was 12%, by 1900 and it was 21% & today it’s 85%. We now live in a world where more than 4 out of 5 people can read, the majority of whom have instant access to essentially all the world‘s knowledge.”
44/ This is something to watch out for: the working age population crisis in most countries could be solved.
45/ If you think extending your lifespan isn’t for you, Read this.
46/ A dab of optimism goes a long way in the discovery of the new 💫
Wish I read this book earlier.
Time to make some changes to the epigenome.
Aging is a disease. (X9999)
End of Thread.
Wish I read this book earlier.
Time to make some changes to the epigenome.
Aging is a disease. (X9999)
End of Thread.
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