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Dr Musa Mohd Nordin Profile picture
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28 Jun, 4 tweets, 2 min read
Selepas kajian Sepanyol, kajian UK juga sahkan bahawa:
1. Kombinasi AstraZeneca(AZ)-Pfizer(P) natijahkan respon antibody & sel memori melebihi AZ-AZ
2 Respon antibody tertinggi dgn P-P
3 Respon sel memori tertinggi dgn AZ-P

bbc.co.uk/news/health-57…
Kombinasi AZ-P:
1. atasi risiko darah beku AZ yang jarang berlaku namun lebih tinggi jika umur<50thn
2. tingkatkan perlindungan dari covid termasuk mutasinya
3. kombinasi lebih anjal
4. atasi isu kurang bekalan vaksin
MOH & JKJAV mesti pertimbang ASAP

reuters.com/business/healt…
Yg telah kena COVID, hanya perlu 1 dos Pfizer BUKAN 2!
COVID+Pfizer tingkatkan antibody 50X ganda!
Mcm ambil 2 dos Pfizer!
MOH & JKJAV jgn membazir vaksin Pfizer dgn memberi 2 dos kpd bekas pesakit COVID!
Alihkan 730K dos kpd yg tidak pernah kena covid.

nature.com/articles/s4159…
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More from @drmusanordin

Dr Musa Mohd Nordin Profile picture
26 Jun
InfectiousDisease 101
In reality-No cases of ID are unlinked!
By it’s very virtue, ID means it’s linked from 1 case to another.
Sporadic or Unlinked is a temporary designation until investigation ie Contact Tracing (CT) uncovers the link-often part of a cluster or outbreak.
1st QR-based visitor logs tool for CT was @Selangkah_my Launched 5/5/2021
@my_sejahtera Check-In was launched 2/6/2021
What sets them apart?
1. The level of Analytic Sophistication
2. The ease of use for Health Care Workers (HCW)
CT automation means sifting through records of visitor logs & DO NOT require MANUAL corroboration.
By using patient’s phone number, @Selangkah_my algorithm sift thru millions of records, to create a list of “probable close contact”, ranked by its importance.
Read 12 tweets
Dr Musa Mohd Nordin Profile picture
22 Jun
Agree our COVID-19 know how is evolving.
But needs to prioritise SCIENCE centric pandemic strategies.
Sanitised from Politics!
eg boosting coverage for Swak elections
Haven’t they learnt from Sabah PRN fiasco?

thestar.com.my/news/nation/20…
Good SCIENCE would prioritise vaccine coverage in HIGH INFECTION states!
Labuan-2109/100K
NS-707
KL-451
Sgor-394
S’wak-301
Sabah-Lowest Vaccine Coverage 12%
May sort out >70% of the nation’s COVID-19 nightmare!
And it makes good ECONOMIC sense too!
Sgor is the powerhouse of the nation.
Sgor contributed- 24.2% GDP
KL-16.4%
Sarawak-9.6%
Yet Sgor has the second lowest vaccine coverage
Is this political vendetta?
Just asking!

google.com.my/amp/s/themalay…
Read 4 tweets
Dr Musa Mohd Nordin Profile picture
22 Jun
11-point KPIs of Public Health to mitigate & en-route to exit the COVID-19 pandemic.
5 KPIs focuses on a speedy and effective FTTIS response.

6 KPIs offers tangible metrics which are science based, realistic and doable.
If we carefully monitor these datasets it will enable, empower the authorities to:
a. gradually roll out our economic activities i.e. safety@work
b. re-open our schools i.e. safety@school
c. allow more social and sports programs i.e. safety@community
After >1 yr in operation, the crisis preparedness response centre (CPRC) should be reviewed & evaluated:
1. To strengthen its TOR
2. To better function as the nation’s COVID Nerve Centre
3. To reinforce public trust in the government’s pandemic response
Read 4 tweets
Dr Musa Mohd Nordin Profile picture
16 Jun
Public Health (PH) Metrics to determine 3 Phases of National Recovery Plan is:
1 Not good Science
2 Random in nature
3 No tangible retrospective or prospective  data stipulated.
Will NOT Mitigate Pandemic.
Only buys time to later unleash another COVID wave when the MCO is eased. Image
Attached is a combination of Key Performance Indicators (PH) to Mitigate the Pandemic En-Route to Exiting it.
The first 5 KPI emphasizes the Critical Importance of a Warp Speed FTTIS Response.
This is the back to basics of effective & efficient COVID-19 Pandemic Management. Image
The next 6 KPI offers Tangible Data which are:
1 Science-based
2 Realistic and
3 Doable
Meticulous & consistent monitoring of these datasets will direct the:
1 Economic rollout Safe@Work
2 Re-opening of schools Safe@School
3 Viability of social & sports programs Safe@Community Image
Read 5 tweets
Dr Musa Mohd Nordin Profile picture
15 Jun
Scotland Study on Vaccine Effectiveness (VE) of 2 doses AZ & Pfizer doses against all COVID and Symptomatic Infections.
Pfizer vaccine provides excellent protection against Delta variant
Less protection with AZ thelancet.com/journals/lance… [1]
Is it time to consider boosting AZ with Pfizer as second dose?
Heterologous boosting is safe [2]

thelancet.com/journals/lance…
Interim safety analysis in UK mix-and-match study, showed increase systemic AEFI in AZ-Pfizer heterologous vaccine schedule compared to the AZ-AZ , Pfizer-Pfizer homologous group.
And associated with increased paracetamol use.
Reassuring that the systemic AEFI were short-lived[3]
Read 11 tweets
Dr Musa Mohd Nordin Profile picture
8 Jun
KKM mesti amanah & cekap dlm komunikasi
Semua pasti gembira dgn tren kes COVID yg menurun
Tetapi ini mesti diimbangi dgn ujian COVID yg mencukupi
Ini penting utk mempastikan kita mengesan bilangan kes COVID setepat mungkin
Yaitu kita tidak under-diagnos bilangan kes dinegara kita
Utk mengetahui kita telah mengawal pandemik dgn baik, kadar ujian positif COVID mesti <5%
Kadar positif ini ditentukan oleh WHO
Rajah menunjukkan bahawa kita gagal utk mencapai kadar positif ini
Maknanya masih banyak kes didalam negara kita yg tidak dikesan dgn ujian massa COVID
Kita boleh anggarkan kes harian COVID dgn kaedah berikut
Kadar kematian diMsia =0.56% [ (3536 kematian/627652 kes) X 100% ]
Maka jika pada 8 Jun 2021 kita rekod 76 kematian, maknanya bilangan kes COVID sepatutnya  76/0.56 X 100 iaitu 13,571.
Tetapi kita hanya merekod 5,566 kes
Read 8 tweets

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