Share this page!

Dr Musa Mohd Nordin Profile picture
Twitter logo
15 Jun, 11 tweets, 4 min read
Scotland Study on Vaccine Effectiveness (VE) of 2 doses AZ & Pfizer doses against all COVID and Symptomatic Infections.
Pfizer vaccine provides excellent protection against Delta variant
Less protection with AZ thelancet.com/journals/lance… [1]
Is it time to consider boosting AZ with Pfizer as second dose?
Heterologous boosting is safe [2]

thelancet.com/journals/lance…
Interim safety analysis in UK mix-and-match study, showed increase systemic AEFI in AZ-Pfizer heterologous vaccine schedule compared to the AZ-AZ , Pfizer-Pfizer homologous group.
And associated with increased paracetamol use.
Reassuring that the systemic AEFI were short-lived[3]
Pfizer booster triggered a stronger and more robust antibody response than 2 doses of AZ. [3,4]
The neutralizing antibody increased 7X after a booster Pfizer dose, doubled that with a second AZ dose in the Spanish study [4]

reuters.com/business/healt…
The IgG antibodies were 30-40X higher than in a control group who received only 1 AZ dose.
Only 1.7% reported systemic AEFI namely headache, myalgia and malaise [5] google.com.my/amp/s/www.news…
Malaysia has a window of opportunity to boost the millions of first dose AZ vacinees with a second Pfizer dose and achieve a better immune response and hence protection namely against the Delta virus. [6]
Many Western nations are immunizing their younger vacinees (less than 60 years old) on AZ first dose with a second mRNA vaccine dose due to the relatively increased risk of blood clots (TTS) [7] google.com.my/amp/s/amp.fran…
JKJAV & MOH need to consider these various vaccination strategies, inc single dose mRNA vaccines in previous COVID patients, prolonging second dose (with careful genomic surveillance) within the context of restricted and delayed vaccines supply chains reuters.com/business/healt…
These break-through vaccine strategies can only be realised if the experts are thinking ahead & MySJ app is robust & contemporary [9]

codeblue.galencentre.org/2021/05/17/mas…
Even more critical now with the rapid transmissibility of the new variant which is challenging the vaccine rollout programs of the better immunised nations eg UK , US, Canada [10] google.com.my/amp/s/www.wsj.…
@threadreaderapp unroll

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with Dr Musa Mohd Nordin

Dr Musa Mohd Nordin Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @drmusanordin

Dr Musa Mohd Nordin Profile picture
16 Jun
Public Health (PH) Metrics to determine 3 Phases of National Recovery Plan is:
1 Not good Science
2 Random in nature
3 No tangible retrospective or prospective  data stipulated.
Will NOT Mitigate Pandemic.
Only buys time to later unleash another COVID wave when the MCO is eased. Image
Attached is a combination of Key Performance Indicators (PH) to Mitigate the Pandemic En-Route to Exiting it.
The first 5 KPI emphasizes the Critical Importance of a Warp Speed FTTIS Response.
This is the back to basics of effective & efficient COVID-19 Pandemic Management. Image
The next 6 KPI offers Tangible Data which are:
1 Science-based
2 Realistic and
3 Doable
Meticulous & consistent monitoring of these datasets will direct the:
1 Economic rollout Safe@Work
2 Re-opening of schools Safe@School
3 Viability of social & sports programs Safe@Community Image
Read 5 tweets
Dr Musa Mohd Nordin Profile picture
8 Jun
KKM mesti amanah & cekap dlm komunikasi
Semua pasti gembira dgn tren kes COVID yg menurun
Tetapi ini mesti diimbangi dgn ujian COVID yg mencukupi
Ini penting utk mempastikan kita mengesan bilangan kes COVID setepat mungkin
Yaitu kita tidak under-diagnos bilangan kes dinegara kita
Utk mengetahui kita telah mengawal pandemik dgn baik, kadar ujian positif COVID mesti <5%
Kadar positif ini ditentukan oleh WHO
Rajah menunjukkan bahawa kita gagal utk mencapai kadar positif ini
Maknanya masih banyak kes didalam negara kita yg tidak dikesan dgn ujian massa COVID
Kita boleh anggarkan kes harian COVID dgn kaedah berikut
Kadar kematian diMsia =0.56% [ (3536 kematian/627652 kes) X 100% ]
Maka jika pada 8 Jun 2021 kita rekod 76 kematian, maknanya bilangan kes COVID sepatutnya  76/0.56 X 100 iaitu 13,571.
Tetapi kita hanya merekod 5,566 kes
Read 8 tweets
Dr Musa Mohd Nordin Profile picture
6 Jun
Case & death curve is virtually vertical!
FTTIS & Vaccine Rollout under-par
MOH & JKJAV recalcitrant in failed modus operandi
S’gor-4th highest Infection Rate
But has lowest CFR-NS (0.51%), S’gor (0.45%), P’ng (0.31%)-Hmm!
< National CFR Average (0.54%)
9 states >National Average ImageImageImageImage
Lessons from COVID-19 Infection Rates VERSUS Vaccination Rates Breakdown by STATES:
1. National Coverage at 7.1% is abysmal.
2. S’pore is 39%
3. All states should be like Putrajaya – 47% uptake
4. OR focus on HIGH Infection States to plunge the spiralling cases & deaths Image
5. S’gor with 4th HIGHEST Infection Rate has 2nd LOWEST coverage!
6. MOH & JKJAV is this political vendetta? Just asking!
7. Why is Sabah’s coverage lowest at 5.6% when S’wak with similar demography is nearly double at 10.1%
8. Don’t wait like HIDE 14 months later to analyse! Image
Read 4 tweets
Dr Musa Mohd Nordin Profile picture
30 May
Hello! MOH collapsed itself with some help from black sheep M’sians!
Since Oct 2020, when MOH did not RETEST nor QUARANTINE Sabah returnees it unleashed the 3rd Wave
The MOH is SET in it’s inefficient & ineffective FTTIS
MOH must RESET to Rapid Response FTTIS
Use RTK-Ag TESTING
Remove Rate Limiting PCR from work-chart!
Digitize & Automate FINDING & TRACING
ISOLATE promptly
Digitize Home Monitoring for Cat 1&2
SUPPORT with basic essentials

drmusanordin.com/2021/01/15/ftt…
Boost Vaccine Confidence
Ramp up VACCINE Rollout
Prioritize High Infection States & Outbreak Areas NOT Elections!
Allow private healthcare to procure & administer
Delay Vaccine Second Dose
Single Pfizer/AZ dose in those with prior #COVID19

drmusanordin.com/2021/05/12/tow…
Read 4 tweets
Dr Musa Mohd Nordin Profile picture
25 May
This is a touching personal account of a Malaysian family living with COVID-19 in the UK.
@rahmahghazali
The family is empowered in the UK
with smart risk communication that enhances knowledge, information and skills. (1)

threadreaderapp.com/thread/1396418…
We have a technocrat who rattles out numbers and parrots paternalistic nuances daily.

And a condescending politician who barely understands the repercussions of the poorly thought and off the cuff SOPs. (2) theedgemarkets.com/article/confli…
National Health System (NHS) aka MOH offers home testing with rapid test kits.
Our MOH is obsessed with PCR which burdens our labs & only gives delayed results unlike RTK-Ag kits!
I have lobbied for affordable if not free test kits since Mar 2020, but fell on deaf MOH & NSC ears.
Read 11 tweets
Dr Musa Mohd Nordin Profile picture
20 May
Community Testing (ComT) by @stfc_selangor
MOH “HIDE” the data @Selangkah_my “FINDS” with big data analytics & machine learning
STFC Digital VS MOH Manual
Stop Fire-Fighting!
MOH Contact Tracing failed
Rollout ComT to detect sporadic cases & bust clusters
threadreaderapp.com/thread/1365838…
MOH burdens our Health Care Workers (HCW) with manual labor & paperwork!
In an era of Data Science & AI this is jurassic work culture & punishes an already fatigued work force of HCW!
The MOH must STOP Fire-Fighting!
The MOH Contact Tracing has absolutely failed! (2) ImageImage
We are facing a COVID-19 Catastrophe!
MOH must listen to Data Scientists & rollout the Community Testing programs in order to detect the 80% sporadic cases & bust the clusters (3)
codeblue.galencentre.org/2021/05/11/dg-…
Read 5 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

Like this author's thread?

Get emails when @drmusanordin has new unrolls!

Check out other threads from @drmusanordin!

Read all threads by @drmusanordin

:(