@DocWoc71 @CarlosdelRio7 @cla_cor @SochinfOficial @BrendaCrabtreeR @ManucoMd @MInternapy @medpedshosp How come this plot says the vaccine is effective? Once someone is infected during a single dose, he/she will never be infected after 2nd dose- either the person will die or recover. COVID reinfection is rare. Therefore, effectiveness after the second dose will always be higher! Image
@DocWoc71 @CarlosdelRio7 @cla_cor @SochinfOficial @BrendaCrabtreeR @ManucoMd @MInternapy @medpedshosp Another point here is that this is large-scale data. 10.2 million participants. This finding is a big deal. The plot clearly shows that infection is higher in one dose vax people than unvax people. If the vaccine helps spread the virus, many unvax people suffered from it.
@DocWoc71 @CarlosdelRio7 @cla_cor @SochinfOficial @BrendaCrabtreeR @ManucoMd @MInternapy @medpedshosp Calculate effectiveness this way- make sample of the same amount of vaxed and unvaxed people. Subtract no. of cases from one dose vax people from the cases of unvax people. Becasue this amount of people would catch virus anyway if they were vaccinated. now find effectiveness.
@DocWoc71 @CarlosdelRio7 @cla_cor @SochinfOficial @BrendaCrabtreeR @ManucoMd @MInternapy @medpedshosp If vaccine effectiveness is not calculated this way, anyone can make a vaccine or medicine which can kill every potential covid vulnerable people during one dose and can claim 100% effectiveness after the second dose.
@DocWoc71 @CarlosdelRio7 @cla_cor @SochinfOficial @BrendaCrabtreeR @ManucoMd @MInternapy @medpedshosp Correction- right hand side of the first equation: covid cases among single vax people

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More from @mahmudme01

21 Aug
@EricTopol In winter (outdoor temp at 5C), 14 fold decreases, and in summer (outdoor temp at 18C) 2 fold decreases. They did not mention the place. I would check the humidity. Now our study suggests 12-13C WBT is the most infectious. Therefore it was safe with windows open in winter. 1/ Image
@EricTopol However, in summer when windows were open WBT could be near to 12-14C. It will depend on humidity as well. They said something bizarre in the discussion. In winter, natural ventilation is low which is related to diffusion. But when you keep windows open you expect convection. 2/
@EricTopol Their argument about ventilation is not the right thing here. In both climates, they kept windows open and got two different outcomes. The temperature and relative humidity which has played the ultimate role here. Therefore, when you ventilate you have to be careful on this. 3/
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