Math is precise, but doesn’t make it accurate. Formulas health economists use calculate a drug’s value rely on uncertain human inputs. @SpeakerPelosi, don’t import this math from Europe. Errors can brand a drug as “not worth it” even when it is. Help patients by fixing insurance.
I’m not saying that one can’t attempt to appreciate how much value a drug generates for society. I’m saying that one should be very careful about math that attempts to override the market to set prices. The math can and should be improved. Here’s how. global-uploads.webflow.com/606ac6e3ee6c27…
And if you are curious about why price controls based on bad math would kill innovation, here’s a step by step explainer of the murdering process. nopatientleftbehind.docsend.com/view/b65fjkcdi…
Solution to affordability is to reform insurance by lowering out of costs. Why is there even a copay for cancer drugs or insulin or a medicine to treat depression or osteoporosis? Who fakes those things to get those drugs? No one.
Congress already outlawed discrimination by insurance against patients based on their pre-existing condition. OOP costs are just discrimination against patients’ emergent conditions. Outlaw them! OOP should stand for “out-of-premium”. nopatientleftbehind.org

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Peter Kolchinsky

Peter Kolchinsky Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @PeterKolchinsky

13 Jul
Hmmm… Drug companies develop meds to keep people out of hospitals, go out of their way to offer patients copay assistance, & get vilified & sued for it. By contrast, hospitals hound patients mercilessly for last $. How will Congress prioritize? @NPLB_org axios.com/hospital-billi…
If you want some tips on how to deal with predatory hospital billing, check out articles on nopatientpeftbehind.org. There is advice on who to call, what to say, what not to sign, etc. And sadly lots of people who have been left behind. We’re working on solutions. @NPLB_org
And if that axios link didn’t work for you. Lots of related articles on hospital predatory billing. axios.com/hospitals-pati…
Read 4 tweets
11 Jul
Money laundering. Hospitals & clinics buy drugs at lower prices from drug company but sell them to patients/insurance at much higher prices, keeping difference to pay own costs (instead of directly charging more for their services). nbcnews.com/nbc-out/out-he…
This is essentially money laundering. The public gets the impression that the clinic/hospital costs are lower & that drugs are much higher. The trouble is that eventually such drugs go generic, ending the scam.
Clinics that have been marking up HIV drugs for years are now shutting down as those drugs go generic. They would have to charge full price for their services to stay open but seems insurance won’t pay those rates.
Read 13 tweets
16 Jun
If best of biopharma industry were incarnated, would be as my friend Paul Hastings @phastings14, CEO of Nkarta, now Chair of BIO @IAmBiotech, & a good soul. Here’s his story & call for reforms: Lower OOP & make drugs go generic w/o undue delays. @NPLB_org vimeo.com/octo8er/review…
What Paul speaks to is very much aligned with the reforms supported by No Patient Left Behind (nopatientleftbehind.org), an organization I helped start and of which Paul is a personal supporter (see Life Science Builder page), as my firm and I support BIO. 2/8
Paul’s comments will make rent-seekers in our industry uncomfortable (companies that have gotten good at milking old drugs for high profits as if they still merit more reward for having been recently invented). Still, I know many within those companies who agree with Paul. 3/8
Read 8 tweets
7 May
Some think patents stand in way of making more vaccines. They don’t. Skill & money do. Just as most of us couldn’t replicate Mona Lisa (no IP there), few can make advanced vaccines. Vaccine companies have already partnered w/ all skilled producers they could find to make doses.
The reason they have already liberally partnered is b/c incentives were there to do so & competition among companies spurred them to get to market first. All those big contracts offered enough reward that innovators shared their knowledge & reward w/ manufacturing partners.
Anyone who didn’t partner with others to expand manufacturing knew that other companies would to sell more doses first, shrinking market for others (especially since wasn’t always evident there would be a long term booster market for laggards).
Read 18 tweets
26 Apr
This Nature paper makes strong case that any COVID, not just serious disease & hospitalization, jacks up risk of many health problems for many months thereafter (long COVID). What’s it mean for vaccines? Durably high protection matters, & boosters. nature.com/articles/s4158…
More specifically, it means that when you hear about vaccines that protect by 70% but claim “yeah, but protects 100% against severe diseases”, know that the 30% residual risk of getting even mild-moderate COVID comes with more risk than we thought. It’s risk worth avoiding.
So right now, get whatever vaccine you can. mRNA seems better than adenoviral and inactivated vaccines. Get booster when offered, both to protect against new variants & old ones, b/c immunity wanes.
Read 14 tweets
28 Mar
Do patient groups perceive drug price controls (HR3) will end progress in treatment of many diseases? Cancer, Alzheimer’s, Parkinson’s... done. HR3 not benign. Price controls always kill investment in risky R&D. No “alternative” economics on that point. timmermanreport.com/2021/03/a-glim…
Some patient advocacy groups I’ve spoken with say “we don’t want to be seen defending drug industry”. And yet, as w/COVID, that’s who develops the treatments- that’s where hope comes from. What’s the point of having standing and pathos if you won’t use it to defend what’s right?
Some say “no, NIH invents drugs.”. They misunderstand. NIH builds foundation but not the product. It makes prototypes at best. But it’s takes the $160B of R&D each year to bring ~50 drugs/year to market... to patients. nopatientleftbehind.docsend.com/view/mxht62ee3…
Read 11 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

:(