#AspenKidney Preservative management of CKD: life sustaining conservative management, delay dialysis by pharmacological and modifying diet and lifestyle.
He says even though we closed the book (MDRD study) on low protein diet 30 years ago we are reopening the book.
low protein 0.6 to 0.8 g/kg
Very low protein diet 0.3 g/kg
#AspenKidney
low protein 0.6 to 0.8 g/kg
Very low protein diet 0.3 g/kg
#AspenKidney
@kamkalantar shows off the shiny new 1A low protein guideline from KDOQI. 🤦
pbfluids.com/2021/05/1a-no-…
pbfluids.com/2021/05/1a-no-…
Showing Tuttle data showing GFR skyrocketing to 165 ml/min after amino acid infusion. nejm.org/doi/full/10.10… 
This explains the acute drop in GFR when patients switch to low protein diet. This is an acute hemodynamics effect and should be ignored in long term outcome (as we do in the SGLT2i studies) He says if you ignore this in MDRD the study becomes positive. #AspenKidney
Kam has all of his patients do regular 24 hour urine to monitor K, Na, and dietary protein. Urine urea nitrogen to protein intake calculator is here: nephron.org/nephsites/nic/… #AspenKidney
Lang based diet to improve mortality in CKD. #AspenKidney
• • •
Missing some Tweet in this thread? You can try to
force a refresh
