Many thanks @chrislhayes for hosting me tonight @allinwithchris as I break down what’s working and what’s working not as well with our COVID19 vaccines vs delta variant 
First point: there are 2 “performance features”
1. The vaccines were released through EUA because of their high level of protection vs symptomatic + severe illness + death.
2. Later studies from Israel UK showed vaccines also halted asymptomatic infections virus shedding
1. The vaccines were released through EUA because of their high level of protection vs symptomatic + severe illness + death.
2. Later studies from Israel UK showed vaccines also halted asymptomatic infections virus shedding
Versus delta, that first performance feature mostly still holds, with the possible exception of those on immunosuppressive Rx or old age who might benefit from a 3rd immunization as now practiced in Israel 🇮🇱 for example
The more problematic is second performance feature such that some vaccinated people with breakthrough infections can still shed lots of virus, hence the new masking guidance for vaccinated people. Unclear if 3rd immunization could also stop virus shedding in breakthrough cases?
Also this week a new @NEJM report that longCovid can occur in vaccine breakthrough. This is a study also from Israel 🇮🇱 with UK variant nejm.org/doi/full/10.10…
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