The idea that Delta somehow changes the risk benefit for kids attending school is literally the dumbest idea I've heard

Unless a new variant has an IFR 10-fold higher in that age group, the net benefit is to continue school in person

School has mental and physical benefits
It has benefits on upward mobility, socioeconomic status, equality, civics, society.
It was always a bad idea to close schools. It was a forgivable bad idea in the spring of 2020. By the fall of 2020, the data were clear and it was no longer a forgivable mistake. By 2021 It's criminal to keep it closed any longer
Many of the children attending school will have antibody evidence that they have encountered SARS COV 2.

They are likely at less of a risk now than before.
The risk of kids spreading to their vaccinated parents is incredibly low. Not even in the ballpark needed to even entertain the idea of keeping schools closed.
Apparently creating a social media platform that allows people who have never thought through a complex policy decision in their life to make strong proclamations and be selectively covered by reporters who share those anxieties was a bad idea
Closing public schools year after year is a type of voter suppression. You are robbing generation of kids, disproportionately poor and minority, from the tools to engage in political processes. It is an insidious and poisonous voter suppression.

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More from @VPrasadMDMPH

1 Aug
Crossed the 300 peer review publication mark recently #nomedicalwriters

Here is what I learned over 12 years of publishing

1. Don't include too many authors...
You have to type their name, affiliation AND email into those damn submission portals
God help 30+ collaborators!
2. Well, if someone is willing to submit the paper, maybe they do deserve to be a co-author after all
#letsnotbehasty
3. If the journal asks you to suggest reviewers, you will probably suggest people you think will like the paper or people who like you
#nohaters
Read 28 tweets
29 Jul
I hope real experts in EBM know that the idea cloth masks "work" on vaccinated people with >50/100k cases SUMMED over 7 days with delta, but not pre-delta, & not at lower case rates, is actually....

100% MADE UP
Like, I hope that masks have not been so politicized and so linked to virtue that the last intelligent person in biomedicine actually thinks this is evidence based anything
Instead, what it is is the APPEARANCE of doing something, as we wait for the inevitable break in the pandemic trajectory
Read 7 tweets
29 Jul
I appreciate this thread by @SarahKarlin an excellent biotech/ regulatory reporter

Some thoughts on Pazdur's comments [thread]
First, all this fiasco is due to Rick himself!
STAT reports that he advised FDA to approve aduhelm by AA, which drew attention to the pathway

The pathway had been abused for years in cancer, but few cared; now all eyes on it.

He has only himself to blame for the attention!!
Next, as background. FDA lets cancer drugs come to market that improve survival AND some that shrink tumors (RR) or slow their growth past arbitrary thresholds (PFS)

The ratio is what, would you guess?
5:1?
4:1?
....
Read 15 tweets

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