1/ Breaking down breakthrough infections: a short 🧵.
As more people are vaccinated w/CoV-19 vaccines, we hear more about so-called breakthrough infections being reported among vaccinated people, which can be confusing.
2/ The MAIN PURPOSE and value of the CoV-19 vaccine is to PREVENT SERIOUS INFECTIONS, not any infection or milder infections.
3/ Breakthrough cases for any vaccine are expected as more people are vaccinated because no vaccine is 100% protective. And the more people that are vaccinated, the more mild "breakthrough" cases we would expect.
4/ So, calling mild or asymptomatic cases breakthrough cases is misleading in that these less serious infections are not what the vaccine is really intended to prevent.
5/ The truth is that CoV-19 vaccines are HIGHLY PROTECTIVE against serious infections leading to hospitalization and/or death for the all commonly circulating SARS-COV-2 viruses in the US that cause COVID-19, including the Delta variant.
6/ For example, over the past 30 days in King County, Washington:
- 81% of cases are not fully vaccinated
- 89% of COVID-related hospitalizations are not fully vaccinated
- 91% of COVID-related deaths are not fully vaccinated.
7/ During this time period, residents who are NOT fully vaccinated were:
- 10 times more likely to test positive for COVID
- 15 times more likely to be hospitalized for COVID-19
- 12 times more likely to die due to COVID-19-related illness.
8/ There are 1,450,000 FULLY-VACCINATED people in King Co. as of July 16th. Among the fully-vaccinated, there have been:
- 1,489 CoV-19 cases = 0.103% (1/10th of 1%)
- 62 hospitalizations = 0.004% (4 thousandths of 1%)
- 11 deaths = 0.001% (1 one-thousandth of 1%)
9/ So: the likelihood of a vaccinated person developing "breakthrough" CoV-19 is currently LOW, but can happen & is usually not severe. Some of these can spread the infection to others. But it is very uncommon.
10/10 CoV-19 vaccination works extremely well in preventing serious CoV-19 infections, as intended. Vaccinated people are MUCH, MUCH less likely to develop and spread CoV-19 infections than unvaccinated people.

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More from @DocJeffD

23 Jun
1/ CDC's vaccine safety team finds a likely association between mRNA vaccines & myocarditis in adolescents & young adults. Onset usually within 7 days after dose 2, males >> females. But, risk is low compared with benefits of vaccination...
2/ Benefits of vaccination in preventing CoV-19 cases, hospitalizations & deaths are great compared w/ low risk of myocarditis, & vary w/ age/gender.

Since pandemic began, 2,767 CoV-19 deaths were reported in 12-29 year olds w/ 316 deaths reported since April 1, 2021.
3/ Additional benefits of vaccination not mentioned above include protection against multi-system inflammatory syndrome in children & adults (MIS-C, MIS-A), long-term symptoms (long Covid) from CoV-19 infections, & against new, more dangerous variants of concern.
Read 6 tweets
14 May
1/ A few thoughts on CDC’s new mask guidance, vaccination & CoV-19 risk.

Vaccinated people have a VERY high level of protection vs CoV-19 compared to unvaccinated with a MUCH LOWER chance of getting sick if exposed or spreading CoV-19 to others.
2/ When unvaccinated people gather indoors, they are at risk of both getting CoV-19 themselves as well as spreading it to others, especially if masks are not worn.
3/ CDC recommends vaccinated people no longer need to wear masks for most activities indoors or out, while unvaccinated people should continue to do so, especially indoors.

However, it’s not easy to know who is/is not vaccinated in public spaces!
Read 13 tweets
12 Apr
1/ What does remaining in Phase 3 of the Governor’s Healthy Washington Roadmap to Recovery mean for King County?

⚠️ Don’t let your guard down! ⚠️ This is definitely not an “all clear” signal. We don’t stop wearing seatbelts just because we haven’t had a crash recently...
2/ We are MUCH closer to putting the worst of the pandemic behind us, but not quite out of danger yet. The potential for a severe surge in cases & hospitalizations remains real until more of us are vaccinated.
3/ For the time being, we all need to continue taking COVID-19 precautions seriously. This will protect us, our family members, friends, co-workers, our community & our economy as vaccinations increase.
Read 8 tweets
22 Feb
Why are COVID-19 cases falling and what does it tell us about where the pandemic is heading? A few thoughts:
1/
Factors contributing to recent surge(s) are decreasing. These include holiday travel/get togethers, more activities & socializing, & general increase in indoor time during fall & winter that facilitate CoV-19 transmission through airborne spread & effects of low humidity. 2/
Restrictions on indoor and other activities (Governor’s directives in WA state: travel advisory, mask use, distancing) work and helped decreased spread. 3/
Read 20 tweets
29 Jan
With more dangerous CoV-19 variants, we must improve CoV-19 prevention in all aspects of our lives, incl. mask quality & fit, limiting time w/others, avoiding crowded indoor spaces, increasing distance from others, & getting vaccinated when it’s your turn. On masks: 1/
Cloth masks are recommended by CDC for use by the public. Cloth face masks were initially recommended to prevent someone w/CoV-19 from spreading the virus to others. This is especially important because people can spread the infection to others before they appear or feel ill. 2/
Recent studies suggest cloth face masks can also provide protection to the wearer. How well it protects depends on how well it's made & fits (e.g. the type & # layers of fabric). At this time, CDC only recommends N95 masks & surgical masks for health care workers (HCW) 3/
Read 17 tweets
12 Jan
In 2010, I noted lessons from the 2009 H1N1 influenza pandemic, incl. epi/surveillance, healthcare system response, communication, mitigation strategies, & the vaccination program. Regrettably, most are just as relevant today, many opportunities missed. 1/
nap.edu/read/12799/cha…
In 2010, I described racial & ethnic disparities, inadequate public health resources/funding; value of enhanced surveillance methods; hospital overload & PPE shortages; drug distribution problems & perhaps most noteworthy at the moment, challenges w/ the vaccination program. 2/
A few key points on vaccination follow. "The need to rapidly plan and implement a large-scale vaccine distribution & administration system severely taxed local public health capacity..." 3/
Read 11 tweets

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