M Profile picture
25 Aug, 4 tweets, 1 min read
Based on Phase 1 safety data of 82 patients πŸ˜ΆπŸ™„πŸ˜
Matlab I would like to meet the biostatistician who came to the conclusion that an 82 subject study can provide statistical significance in this case. Has to be some really big shot genius & we should learn from the genius. Hats off to the dude.
And then hats off to the the folks at DCGI who found after evaluation of the data submitted to them that this number provided statistical significance enough for nod for next phase approval.
Really interested in finding out which population size is it that Indian trial researchers (not just specific to this vaccine but in general since pandemic) & approval granting teams substitute in denominator to come up with such sample sizes?

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More from @pseudo_sapiens

27 Aug
What is the point of announcing - β€œWe anticipate so many lakh cases in the 3rd wave per day” when despite all of this, the entire country will behave complacently about - Precautions that can prevent such numbers??

And don’t kid yourself about not being complacent because…
1) Go to any market place/mall/shop (I have sample sizes Delhi-NCR) - 80-90% of people will be having a mask hanging in their neck or no mask but a cloth covering their mouths not noses, people will be interacting from close distances while their masks are hanging.
2) Closed space eateries with shared Air space, simple ACs, no air filters functioning at full capacity, with at any given point in time 25-40 people eating with their masks down. The distance between 2 seats in less than an arm!!!
Read 15 tweets
25 Aug
I kid you not.

This absurd pricing where 90% of Cost Price will simply go to Hospitals & Insurance companies as their profit is a situation which is already a reality in some private sector hospitals.

This translates into unaffordable or insanely expensive procedures.
When Foreign Investors or funds make & are allowed healthcare acquisitions worth 1000’s of crores (90% of large scale private hospitals are now owned by these investors) how can we expect that the cost of healthcare will remain rational?
These healthcare acquisition costs are a direct indication that these investments are considered profit yielding entities & by a common sense business corollary you are not going to do a 1600 crore acquisition to do charity & they donot do charity.
Read 4 tweets

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