#akccovid22
FINOFIBRATE IN COVID DISEASE
FINOFIBRATE IN COVID DISEASE
https://twitter.com/drakchaurasia/status/1436636834595893255?s=19
COMMON ANTI-PARASITIC AGENT EASES MOTOR SYMPTOMS, AIDS REMYELINATION IN MS MOUSE MODEL
IVM in autoimmune disease
"ivermectin eased clinical manifestations of experimental autoimmun encephalomyelitis (EAE;an induced autoimmune disease similar to MS in human
multiplesclerosisnewstoday.com/2018/07/13/ant…
IVM in autoimmune disease
"ivermectin eased clinical manifestations of experimental autoimmun encephalomyelitis (EAE;an induced autoimmune disease similar to MS in human
multiplesclerosisnewstoday.com/2018/07/13/ant…
POOR AB RESPONSE TO VACS OR NATURAL COV2 INFECTION
*pts on immunosuppressive drugs
*immunocompromised due to diseases like HIV
*neoplastic blood disorders, leukemia, lymphoma
*hereditary dysfunctions of T and B cells
*pts on immunosuppressive drugs
*immunocompromised due to diseases like HIV
*neoplastic blood disorders, leukemia, lymphoma
*hereditary dysfunctions of T and B cells
DELTA LINEAGE - CLINICAL SPECTRUM
at least 6 variants of delta, expressing clinical spectrum
*resp symptoms+mild hypoxia
*resp symp+trivial or no hypoxia
*gastro-intestinal symp
*neurological/cardiac/hiccups/convulsive disorders/tinnitus+hearing loss
at least 6 variants of delta, expressing clinical spectrum
*resp symptoms+mild hypoxia
*resp symp+trivial or no hypoxia
*gastro-intestinal symp
*neurological/cardiac/hiccups/convulsive disorders/tinnitus+hearing loss
https://twitter.com/drakchaurasia/status/1437120914152300547?s=19
MY TAKE ON COVID TODAY
*OPEN EVERYTHING, RESUME NORMAL LIFE
*NO MASK, NO SANITIZER, NO DISTANCING
*TREAT ANY ILLNESS EARLY AND WITH FULL TREATMENT
*ALLOW ALL TOURISTS AND BUSINESS VISITORS FROM ABROAD
*GIVE PRE-EXPOSURE PROPHYLAXIS TO PEOPLE IN CONTACT WITH FOREIGN VISITORS
*OPEN EVERYTHING, RESUME NORMAL LIFE
*NO MASK, NO SANITIZER, NO DISTANCING
*TREAT ANY ILLNESS EARLY AND WITH FULL TREATMENT
*ALLOW ALL TOURISTS AND BUSINESS VISITORS FROM ABROAD
*GIVE PRE-EXPOSURE PROPHYLAXIS TO PEOPLE IN CONTACT WITH FOREIGN VISITORS
dear friends,this is seemingly too far-fetched.but i believe
need your opinions 🙏
@Covid19Crusher
@Rajnish_IITR
@rajnishgupta59
@Dharmen46587056
@ishan_bhupendra
@BidoliNicola
@Thinkerks
@NavroopSingh_
@amareshskumar
@ICMRDELHI
@veryvirology
@AboutIndia
@Parsifaler
@YonSolitary
need your opinions 🙏
@Covid19Crusher
@Rajnish_IITR
@rajnishgupta59
@Dharmen46587056
@ishan_bhupendra
@BidoliNicola
@Thinkerks
@NavroopSingh_
@amareshskumar
@ICMRDELHI
@veryvirology
@AboutIndia
@Parsifaler
@YonSolitary
KEEP THE PEOPLES AROUND YOUR KIDS, VIRUS FREE.
YOUR KIDS WON'T NEED PROPHYLAXIS
YOUR KIDS WON'T NEED PROPHYLAXIS
IVERMECTIN PROPHYLAXIS FOR SCHOOL GOING CHILDREN
*give ivermectin to all school going children.
*they all are above 10 kg and ivermectin is safe for them.
0.2mg/kg body wt
*give ivermectin to all school going children.
*they all are above 10 kg and ivermectin is safe for them.
0.2mg/kg body wt
IVERMECTIN PROPHYLAXIS FOR SCHOOL GOING CHILDREN
give ivermectin to all school going children.
they all are above 10 kg and ivermectin is safe for them.
0.2mg/kg body wt
weekly for 3 months. reconsider after that, if pandemic not ended.
give ivermectin to all school going children.
they all are above 10 kg and ivermectin is safe for them.
0.2mg/kg body wt
weekly for 3 months. reconsider after that, if pandemic not ended.
UMIFENOVIR IN COVID
"viral load in mild,moderate or asymptomatic pts after being given two doses of Umifenovir(800mg) twice a day,became zero in an average of five days.Pts did not experience any side effects and their symptoms also did not turn severe"
m.timesofindia.com/india/cdri-ach…
"viral load in mild,moderate or asymptomatic pts after being given two doses of Umifenovir(800mg) twice a day,became zero in an average of five days.Pts did not experience any side effects and their symptoms also did not turn severe"
m.timesofindia.com/india/cdri-ach…
IVERMECTIN PROPHYLAXIS
*ivermectin has good prophylactic value for coV2
*half-life of ~18 hrs makes it marginally weak on weekly dosage
*considering it's antiviral dosage of 0.4-0.8mg/kg wt,at least 0.4mg/kg/weekly are needed
*these dosage were effective ~85% in 2nd wave(india)⬇️
*ivermectin has good prophylactic value for coV2
*half-life of ~18 hrs makes it marginally weak on weekly dosage
*considering it's antiviral dosage of 0.4-0.8mg/kg wt,at least 0.4mg/kg/weekly are needed
*these dosage were effective ~85% in 2nd wave(india)⬇️
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*delta needs lesser dosage.
*delta needs lesser dosage.
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irrespective of number of contacts around you, a significantly low viral transmission, may allow you to skip few dosage,
with a faint possibility to contract covid.
*a low grade sporadic use of ivermectin in a community, not only reduces transmission but attenuates virion too
irrespective of number of contacts around you, a significantly low viral transmission, may allow you to skip few dosage,
with a faint possibility to contract covid.
*a low grade sporadic use of ivermectin in a community, not only reduces transmission but attenuates virion too
ARTESUNATE AND DIHYDROARTEMISININS INHIBIT RABIES VIRUS REPLICATION
"artemisinin inhibits replication of flaviviruses by promoting type I interferon production.Therefore, artemisinins act as promising antiviral agents through multiple mechanisms" link.springer.com/article/10.100…
"artemisinin inhibits replication of flaviviruses by promoting type I interferon production.Therefore, artemisinins act as promising antiviral agents through multiple mechanisms" link.springer.com/article/10.100…
JUST AFTER VACS ROLLOUT, WE NEEDED AN ANTI-ADE PROTOCOL
managing the vacs related adverse effects
managing the vacs related adverse effects
https://twitter.com/drakchaurasia/status/1353289514794405888?s=19
WHAT UMIFENOVIR MEANS FOR, "COVID IN INDIA"
in pipeline, in india
china already has data on it
in pipeline, in india
china already has data on it
https://twitter.com/__ice9/status/1330584566550159360?s=19
FRINGE SCIENCES AND IVERMECTIN
a least explored discipline addresses a novel disease
connotation of"fringe science"is that enterprise is rational bt is unlikely to produce good results for a variety of reasons,including incomplet or contradictory evidence
explorable.com/fringe-science
a least explored discipline addresses a novel disease
connotation of"fringe science"is that enterprise is rational bt is unlikely to produce good results for a variety of reasons,including incomplet or contradictory evidence
explorable.com/fringe-science
MY POST ON IMPENDING THREAT OF ADE.
AS EARLY AS 13 DAYS AFTER VACS ROLLOUT
AS EARLY AS 13 DAYS AFTER VACS ROLLOUT
https://twitter.com/drakchaurasia/status/1353293014878150658?s=19
THE MEDIA IN PANDEMIC
"no deaths despite legitimate physician prescriptions increasing from a few thousand per month to nearly 90,000"
"media was confusing legitimate physician-to-patient prescriptions versus illicit use of veterinary version of the drug"
trialsitenews.com/msn-showcases-…
"no deaths despite legitimate physician prescriptions increasing from a few thousand per month to nearly 90,000"
"media was confusing legitimate physician-to-patient prescriptions versus illicit use of veterinary version of the drug"
trialsitenews.com/msn-showcases-…
VACS REPROGRAMMING INNATE IMMUNE CELLS
vacs reprogram immune system?
Following vaccination,innate immune cells had a reduced response to toll-like receptor 4 (TLR4),TLR7 and TLR8–all ligands that play an important role in immun response to viral infection
news-medical.net/news/20210510/…
vacs reprogram immune system?
Following vaccination,innate immune cells had a reduced response to toll-like receptor 4 (TLR4),TLR7 and TLR8–all ligands that play an important role in immun response to viral infection
news-medical.net/news/20210510/…
AMANTADINE IN COVID
Clinical stabilization was achieved in 91% (n=50)of pts within 48 hours after first dose of AMT with further improvement
all patients experienced remission of COVID. In total,93% (n=51) of pts did not require hospitalization during Rx. researchsquare.com/article/rs-493…
Clinical stabilization was achieved in 91% (n=50)of pts within 48 hours after first dose of AMT with further improvement
all patients experienced remission of COVID. In total,93% (n=51) of pts did not require hospitalization during Rx. researchsquare.com/article/rs-493…
A THREAD ON AUTOPSY REPORTS
"Today there was a press conference from pathological institute in Reutlingen,Germany. pathologists Prof. Dr. Arne Burkhardt and Prof.Dr. Walter presented results of autopsies of eight people who died after COVID19 vaccination"
"Today there was a press conference from pathological institute in Reutlingen,Germany. pathologists Prof. Dr. Arne Burkhardt and Prof.Dr. Walter presented results of autopsies of eight people who died after COVID19 vaccination"
https://twitter.com/DrJohnB2/status/1440083804173918215?s=19
INTERFERON INDUCING EFFECTS OF LIQUORICE
effects are dose related, but lower dasage can help regular meds for covid
"still it's possible to use it as interferon inducer, along with regular anticovid treatment"
effects are dose related, but lower dasage can help regular meds for covid
"still it's possible to use it as interferon inducer, along with regular anticovid treatment"
https://twitter.com/drakchaurasia/status/1445334430575251462?t=y4IUyuzWvKeQq9RybfrWVQ&s=19
ASUNAPREVIR IN COVID
can it be better alternative to molnupiravir?
"asunaprevir,but not sofosbuvir and daclatasvir,markedly inhibited CoV-2-induced cytopathic effects in Vero E6 cells.Both RNA and protein levels of SARS-CoV-2 were significantly decreased"
pubmed.ncbi.nlm.nih.gov/34518443/
can it be better alternative to molnupiravir?
"asunaprevir,but not sofosbuvir and daclatasvir,markedly inhibited CoV-2-induced cytopathic effects in Vero E6 cells.Both RNA and protein levels of SARS-CoV-2 were significantly decreased"
pubmed.ncbi.nlm.nih.gov/34518443/
DELTA DOES NOT APPEAR TO MAKE CHILDREN SICKER
"Delta variant of coronavirus does not appear to cause more severe disease in children than earlier forms of virus"
"New data suggests that kids also do not get any sicker from Delta than they did from Alpha"
reuters.com/business/healt…
"Delta variant of coronavirus does not appear to cause more severe disease in children than earlier forms of virus"
"New data suggests that kids also do not get any sicker from Delta than they did from Alpha"
reuters.com/business/healt…
MITIGATING VACS ADVERSITIES
https://twitter.com/drakchaurasia/status/1446773851426201615?t=Cz4JOi1tx9LKFsXpGaj0Zg&s=19
PEOPLE WHO HAVE HAD MILD ILLNESS, DEVELOP ANTIBODY-PRODUCING CELLS THAT CAN LAST LIFETIME
https://twitter.com/RWMaloneMD/status/1446893461458849795?t=_dCUFec1Nl1VACBJZGBQzA&s=09
THE INTERFERON INDUCERS
we have a diverse group of drugs and herbal products inducing IFNs
"clarithromycin was found promising in treatment of influenza virus infection. Leucomycin A3 was also active against influenza virus and enhanced IFN-α production"
ncbi.nlm.nih.gov/pmc/articles/P…
we have a diverse group of drugs and herbal products inducing IFNs
"clarithromycin was found promising in treatment of influenza virus infection. Leucomycin A3 was also active against influenza virus and enhanced IFN-α production"
ncbi.nlm.nih.gov/pmc/articles/P…
CDC APPROVES COVAXIN
"Advancing Safe Resumption of Global Travel During the COVID-19 Pandemic issued on October 25, 2021 and CDC’s Order Implementing Presidential Proclamation on Advancing Safe Resumption of Global Travel During the COVID-19 Pandemic"
cdc.gov/quarantine/ord…
"Advancing Safe Resumption of Global Travel During the COVID-19 Pandemic issued on October 25, 2021 and CDC’s Order Implementing Presidential Proclamation on Advancing Safe Resumption of Global Travel During the COVID-19 Pandemic"
cdc.gov/quarantine/ord…
FLUNARIZINE IN TINNITUS AND VERTIGO FROM INTERNAL EAR DISEASE
perhaps in covid too
"protective mechanism of flunarizine on cisplatin-induced cytotoxicity is associated with direct inhibition of lipid peroxidation and mitochondrial permeability transition"
pubmed.ncbi.nlm.nih.gov/15925198/
perhaps in covid too
"protective mechanism of flunarizine on cisplatin-induced cytotoxicity is associated with direct inhibition of lipid peroxidation and mitochondrial permeability transition"
pubmed.ncbi.nlm.nih.gov/15925198/
"FLORIDA SUMMIT ON COVID" WILL ASSEMBLE IN OCALA
NOVEMBER 6, SATURDAY, 2021
"Dr. John Littell is bringing Pierre Kory,Peter McCullough,Robert Malone, Richard Urso & others to a Florida summit"
“We’re going to come and show people how to end this pandemic”
rescue.substack.com/p/top-doctors-…
NOVEMBER 6, SATURDAY, 2021
"Dr. John Littell is bringing Pierre Kory,Peter McCullough,Robert Malone, Richard Urso & others to a Florida summit"
“We’re going to come and show people how to end this pandemic”
rescue.substack.com/p/top-doctors-…
SOLAR FLARE, GEO-MAGNETISM AND AUTONOMIC NERVOUS SYSTEM
CME affecting human behavior on earth
"daily ANS activity, as reflected by HRV measures, responds to changes in geomagnetic and solar activity primarily during periods undisturbed by solar activity"
ncbi.nlm.nih.gov/labs/pmc/artic…
CME affecting human behavior on earth
"daily ANS activity, as reflected by HRV measures, responds to changes in geomagnetic and solar activity primarily during periods undisturbed by solar activity"
ncbi.nlm.nih.gov/labs/pmc/artic…
GRAVITATIONAL WAVES, MYSTERIOUS UNIVERSE AND LIMITATIONS OF SCIENTIFIC ENDEAVOURS
things we don't know!
"32 of these ripples were detected from pairs of merging black holes, while three others likely come from collision of a neutron star and a black hole"
indiatoday.in/science/story/…
things we don't know!
"32 of these ripples were detected from pairs of merging black holes, while three others likely come from collision of a neutron star and a black hole"
indiatoday.in/science/story/…
SHIFTING PARADIGMS ARE CHARACTERISTICS OF SCIENTIFIC EXPLORATIONS
the unending trails of theories.....
"RIP Dark Matter: Scientists Re-Imagine The Universe With 'Undiscovered Gravity'"
indiatimes.com/technology/sci…
the unending trails of theories.....
"RIP Dark Matter: Scientists Re-Imagine The Universe With 'Undiscovered Gravity'"
indiatimes.com/technology/sci…
AURORAS-VIEW FROM ISS
We were treated to strongest auroras of entire mission, over north America and Canada.Amazing spikes higher than our orbit, and we flew right above centre of ring,rapid waves and pulses all over
#MissionAlpha flic.kr/p/2mH57YX
We were treated to strongest auroras of entire mission, over north America and Canada.Amazing spikes higher than our orbit, and we flew right above centre of ring,rapid waves and pulses all over
#MissionAlpha flic.kr/p/2mH57YX
VIRTUALLY EVERY SMALL AND LARGE MOLECULE CAN BEHAVE DIFFERENTLY IN DIFFERENT PHYSICAL STATES
"scientists have identified 20 phases of water ice — the different ways that bonded hydrogen and oxygen atoms can stack under varying temperatures and pressures"
livescience.com/amp/stable-sup…
"scientists have identified 20 phases of water ice — the different ways that bonded hydrogen and oxygen atoms can stack under varying temperatures and pressures"
livescience.com/amp/stable-sup…
OMICRON - ANOTHER VARIANT TO UNDERMINE COVID?
delta de-escalated and omicron to end the pandemic?
"Omicron patients reported extreme tiredness, mild muscle aches, a scratchy throat and dry cough,doctor told AFP. Only a few had a slightly high temperature"
hindustantimes.com/world-news/scr…
delta de-escalated and omicron to end the pandemic?
"Omicron patients reported extreme tiredness, mild muscle aches, a scratchy throat and dry cough,doctor told AFP. Only a few had a slightly high temperature"
hindustantimes.com/world-news/scr…
OMICRON- FEW UPDATES
no extra infectivity no extra virulence
"neutralizing antibodies will have very weak activity on this variant. On other hand, facilitating epitope of NTD (ADE epitope) is also destroyed by rearrangements of Omicron's Spike protein"
linkedin.com/posts/jacques-…
no extra infectivity no extra virulence
"neutralizing antibodies will have very weak activity on this variant. On other hand, facilitating epitope of NTD (ADE epitope) is also destroyed by rearrangements of Omicron's Spike protein"
linkedin.com/posts/jacques-…
"UN-SEVERE" OMICRON....
https://twitter.com/Covid19Crusher/status/1466196099824242707?t=LleuRtNzZ9Eu1SrF30s_iw&s=19
OMICRON TO END PANDEMIC?
“we already see Omicron has many mutations, more than Delta. More than thirty in a single gene of its spike protein
virus has an unstable genome.
Right now there are reasons to think that Omicron variant could be less pathogenic,”
greatgameindia.com/omicron-end-pa…
“we already see Omicron has many mutations, more than Delta. More than thirty in a single gene of its spike protein
virus has an unstable genome.
Right now there are reasons to think that Omicron variant could be less pathogenic,”
greatgameindia.com/omicron-end-pa…
THE COVID VACS BOOSTERS
blog from Geert Vanden Bossche
"From an immunological point of view, boosters and mass vaccination in general are as harmful as mold on a wall.
vaccine can not prevent infection nor transmission. By again increasing the antibodies (with the booster)
1/1
blog from Geert Vanden Bossche
"From an immunological point of view, boosters and mass vaccination in general are as harmful as mold on a wall.
vaccine can not prevent infection nor transmission. By again increasing the antibodies (with the booster)
1/1
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virus is put under an even higher immune pressure while further expanding its capacity to escape from the vaccinal antibodies (Abs). As a result more infectious variants gain a competitive advantage and hence, will spread stronger amongst the population. This only
virus is put under an even higher immune pressure while further expanding its capacity to escape from the vaccinal antibodies (Abs). As a result more infectious variants gain a competitive advantage and hence, will spread stronger amongst the population. This only
1/3
precipiates and expands the evolutionary capacity of the virus to resist the vaccines. The level of protection WHO has recently been claiming (40%) is anything but due to the vaccines and can only be ascribed to some ‘trained’ innate immunity large parts of the population
precipiates and expands the evolutionary capacity of the virus to resist the vaccines. The level of protection WHO has recently been claiming (40%) is anything but due to the vaccines and can only be ascribed to some ‘trained’ innate immunity large parts of the population
1/4
acquired prior to vaccination as a result of asymptomatic/ mild infection. It is crystal clear, indeed, that none of the C-19 vaccines is capable of blocking transmission, not even by 1 % ! Because vaccinal Abs suppress relevant innate Abs, these vaccines have no capacity
acquired prior to vaccination as a result of asymptomatic/ mild infection. It is crystal clear, indeed, that none of the C-19 vaccines is capable of blocking transmission, not even by 1 % ! Because vaccinal Abs suppress relevant innate Abs, these vaccines have no capacity
1/5
whatsoever to confer sterilizing immunity. Consequently, none of these vaccines help to build herd immunity; on contrary, they generate a breeding ground in vaccinees for more infectious variants, thereby further increasing infection rates and threatening both unvaccinated
whatsoever to confer sterilizing immunity. Consequently, none of these vaccines help to build herd immunity; on contrary, they generate a breeding ground in vaccinees for more infectious variants, thereby further increasing infection rates and threatening both unvaccinated
1/6
and vaccinated. Moreover, vaccinal Abs tend to outcompete innate Abs for binding to SARS-CoV-2 because of their higher affinity for virus. This particularly applies to naive innate Abs (children!) and already explains why C-19 vaccination is at risk of dramatically weakening
and vaccinated. Moreover, vaccinal Abs tend to outcompete innate Abs for binding to SARS-CoV-2 because of their higher affinity for virus. This particularly applies to naive innate Abs (children!) and already explains why C-19 vaccination is at risk of dramatically weakening
1/7
people’s first line of immune defense, especially in children. Our innate immunity is not only well armed to protect against COVID-19 (including all its variants!), but also against a number of other viruses causing acute respiratory disease.
There can be no doubt, therefore,
people’s first line of immune defense, especially in children. Our innate immunity is not only well armed to protect against COVID-19 (including all its variants!), but also against a number of other viruses causing acute respiratory disease.
There can be no doubt, therefore,
1/8
that such an assault of our immune system will have dramatic consequences on both individual and public health.Basically, mass vaccination is now turning Covid-19 into a disease of young and healthy unvaccinated people while enabling the virus to break through both innate and
that such an assault of our immune system will have dramatic consequences on both individual and public health.Basically, mass vaccination is now turning Covid-19 into a disease of young and healthy unvaccinated people while enabling the virus to break through both innate and
1/9
adaptive immune defense of vaccinees due to vaccine-mediated suppression of innate Abs and viral resistance to vaccinal Abs, respectively. For those who didn’t get it thus far, Omicron will repeat that lesson; its teaching will only be a bit tougher and will soon silence all
adaptive immune defense of vaccinees due to vaccine-mediated suppression of innate Abs and viral resistance to vaccinal Abs, respectively. For those who didn’t get it thus far, Omicron will repeat that lesson; its teaching will only be a bit tougher and will soon silence all
1/10
those who are trying to convince their people that they can outsmart the virus and, as they ridiculously claim, ‘stay ahead of the virus’.
*end*
those who are trying to convince their people that they can outsmart the virus and, as they ridiculously claim, ‘stay ahead of the virus’.
*end*
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