To understand what member states got dragged into these horrible agreements, let's go back to the agreement between the commission & member states on producing vaccines, annexed to EC decision C(2020) 4192 from the 18th of June 2020.
In a typical European Commission style, the APAs were "approved for signature on behalf and in the name of the participating Member States by a separate individual Commission decision."
Or in other words - the member states are rubber stamps to the EC decisions.
Or put it more bluntly:
"the Commission can sign on behalf of the Member States intermediary documents enabling the start, continuation and completion of the negotiations."
"As regards the approval of APAs or intermediary documents that set terms and conditions of the APAs or otherwise contain legally binding obligations, THE COMISSION WILL EXCERISE ITSELF THE POWER IT HAS DELEGATED".
Member states are required to acquire the product directly from the manufacturers. It required the member states to sign a contract with the manufacturers.
However, the EC's APA agreement and all the clauses legally bind the member states who did not opt out.
"ONCE CONCLUDED, THE TERMS OF THE APA SHALL BE LEGALLY BINDING ON THE PARTICIPATING MEMBER STATES, EXCEPT FOR THOSE WHO HAVE EXERCISED THEIR RIGHT TO OPT OUT."
"Member States…shall bear any liability…this shall extend to and INCLUDE ANY INDEMNIFICATION OF VACCINE MANUFACTURERS under the terms and conditions of the relevant APA for liability related to the use and deployment of vaccines NORMALLY BORNE BY SUCH MANUFACTURER". #PfizerLeak
I will rephrase what you just read - the member states had to agree to identify the manufacturers with regards to the liabilities of vaccines WHICH THEY NORAMLLY WOULD HAVE CARRY.
Notice the use of past tense. This APA agreement has enforced a new legal "normal".
Let us dig deeper.
"A permanent solution to the COVID-l9 crisis is most likely to be brought about by the development and deployment of a SAFE and EFFECTIVE vaccine against the virus"
Safety & effectiveness? HA! Please see my #COptiGate thread:
The negotiating team was made of a limited number of experts from the 6 participating member states with production capacities for vaccines who made "its best effort to take the advice of the steering board into account".
Everyone who were part of the negotiation were required to sign strict confidentiality and no-conflict-of-interest agreements, which also meant that no one who were part of the negotiation were allowed to share any concerns with member states and MEPs. #PfizerLeak
"Before making any final decisions, the Commission will seek independent scientific advice on the state of progress and the available data on quality, safety and efficacy for the vaccine candidate in question."
"For liability arrangements, the joint negotiation team will make its best effort to limit what is required by individual companies for the purpose of indemnification to be included in the terms and conditions of the APA"
Finally, the "we are the world" clause, or "Covid-l9 vaccine as a global public good." which was supposed to provide access for low and middle income countries to these vaccines & IP sharing, especially when it developed with public support".
It is PAINFUL to go over these documents, because the more I read, the more I understand how the EU is being run by undemocratic & non-transparent institutes, who don't give a darn about the safety of EU citizens and the financial burden they inflicted upon them.
Finally, if you have reached here and didn't read my original post on the topic, you should go and read about the crimes against #EU-MANITY, or how the European commission deceived EU member states, MEPs, and EU citizens.
And as always, don't forget to click the "Show replies" below, in case I missed something … because I usually do lol...
Show replies
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This does not look like failed negotiation but a deliberate, well planned move to create a new regulatory landscape and financial reality that will lead to vaccine passports, digital currency, and total power of the EC over EU states and citizens.
Our democracies are in danger.
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Pediatric Moratorium! Adult Use Restrictions! Veterinary Prohibition!
"Codon Optimization in mRNA Vaccines and Gene Therapies: An Assessment of Protein Misfolding Risks and Regulatory Oversight" submitted to the FDA's Vaccines and Related Biological Products Advisory Committee!
Here's the Executive Summary
Objective: This white paper evaluates the scientific evidence and regulatory oversight related to codon optimization in messenger RNA (mRNA) vaccines and gene therapies for both human and animal applications. Its primary goal is to assess whether the potential risks—specifically protein misfolding, aggregation, and associated diseases like amyloidogenesis and prionogenesis—justify a moratorium on this technology’s use. The analysis aims to inform policy by balancing innovation with safety.
Scope: The assessment covers the principles of codon optimization, the mechanisms of protein folding and misfolding during translation, and the risks of amyloid formation and prion-like propagation. It reviews regulatory frameworks, including the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) Chemistry, Manufacturing, and Controls (CMC) requirements. The scope includes a detailed examination of scientific literature—both foundational and recent—such as studies on tissue-specific codon usage, codon context effects, and structural risks in mRNA vaccines. It also analyzes preclinical and clinical safety data, pharmacovigilance reports, and a case study on COVID-19 mRNA vaccines. Additionally, the paper explores implications for veterinary vaccines and food chain safety, concluding with an updated risk management and policy evaluation.
Key Findings: Codon optimization enhances protein production in mRNA-based vaccines and therapies but introduces risks that challenge its presumed safety. New research shows that changing codons—previously thought to be neutral—affects translation speed and accuracy, potentially leading to protein misfolding and aggregation. For example, the cardiomyocyte PAO model reveals that misfolded proteins can cause delayed, severe damage, such as heart failure, broadening concerns beyond brain-related diseases. Data from TissueCoCoPUTs indicate that generic codon optimization often mismatches the translation needs of specific tissues, increasing misfolding risks. In COVID-19 mRNA vaccines, structural issues like excessive G-quadruplex formation may heighten these dangers.
Regulatory oversight, however, falls short. There are no standard tests to evaluate how codon changes affect protein shape or clumping, and long-term monitoring is insufficient to detect slow-developing issues like neurodegeneration or prion-like diseases. The rapid rollout of COVID-19 mRNA vaccines lacked thorough evaluation of these folding risks. In veterinary applications, the use of codon-optimized therapies in livestock raises unresolved concerns about misfolded proteins entering the food chain and environment, potentially affecting human health.
Conclusion on Moratorium
Given the mounting evidence of risk and gaps in oversight, a tiered moratorium is recommended as the most cautious and effective approach:
· Pediatric Moratorium: Codon-optimized mRNA vaccines and gene therapies should not be used in children under 18 until safer practices are developed. This includes using tissue-specific codon designs, conducting 24-month safety studies in primates, and setting limits on G-quadruplex formation. Children’s developing tissues are especially vulnerable, and long-term data are lacking.
· Adult Use Restrictions: New clinical trials for risky mRNA designs—those with heavy optimization, high clumping potential, or rich GC content—should pause. This halt would last until advanced tests, such as Kinetic Folding Assurance (KFA), hidden gene screening, and cross-seeding checks, are required.
· Veterinary Prohibition: Codon-optimized gene therapies in animals entering the food supply should be banned. Evidence from the PAO model and prion diseases suggests a risk of transmissible misfolded proteins, posing a threat to food safety.
This moratorium should persist until:
· Reliable tests for protein folding and clumping are part of regulatory standards.
· Codon optimization accounts for tissue-specific needs and translation timing.
· Independent research verifies the safety of high-risk designs and pediatric use.
· Better monitoring systems track long-term health effects.
This approach marks a shift in how codon optimization is viewed: it’s not just a tool for efficiency but a process that demands careful study of its effects on protein structure and safety over time. By adopting these measures, we can protect public health while still advancing mRNA and gene therapy innovations.
The whitepaper has just been published in my Sub/I\Stack (Link in my pro/I\file)!
I published my first article on codon optimization risks and the COVID-19 vaccine in August 2021 (#COptiGate) and wrote extensively on the topic. This white paper, submitted to the @US_FDA, is my final attempt to highlight our regulators' complete failure.
🚨Microwave Ovens Might Be Risking Your Health! 🚨
Did you know that eating microwaved food could cause blood changes linked to cancer? Russians knew it. Swiss scientist Dr. Hans-Urich Hertel discovered this over 30 years ago, but the microwave industry tried to silence him.
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Dr. Hans-Urich Hertel was a Swiss food scientist who challenged microwave safety. In 1989, he teamed up with Professor Bernard Blanc to study how microwaved food affects us. Their findings? Alarming enough to spark a decade-long battle! #ScienceHeroes #MicrowaveResearch
Hertel and Blanc recruited eight volunteers from a macrobiotic institute in Switzerland. For eight weeks, they ate raw, conventionally cooked, or microwaved foods—like milk and veggies—under strict conditions (no smoking, alcohol, or sex!). Blood tests followed every meal. #MicrowaveStudy #HealthResearch
THE GLOBAL IT OUTAGE YOU WITNESSED WAS NOT AN ACCIDENT!
IMPORTANT! The purpose of this thread is to explain non-IT and to non information/cyber security professionals why I believe the outage you are seeing around the world due to the update from #Crowdstrike is not an accident.
Before we begin - introduction.
Hi everyone. My name is Ehden Biber. I'm known as the person behind #PfizerLeak, and most of my writing here on X/Twitter has been on ph@rma related topics. HOWEVER, my professional work has been information security and cybersecurity.
My credentials include:
· Head of information security in Metro Bank (UK).
· Merck/MSD Information security office for Europe, Middle East and Africa (EMEA).
· Consultant to insurance and financial institutes.
The opinion you are about to read is based on YEARS of experience.
"MEDICAL GENETICS…WILL BE THE SOUL OF PERCISION MEDICINE IN EVERY FIELD"
It is time to expose another member of the W.H.O. science council and her views on genomics and gene therapy (mRNA). Introducing Dr Mary-Claire King.
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Doctor Mary-Claire King is a very known geneticist who has discovered in 1990 BRCA1,which was the first gene for a hereditary form of breast cancer. She is a professor of genome sciences in the university of Washington, Seattle, USA. medgen.uw.edu/people/mary-cl…
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Her later work was focused on the genetics of schizophrenia, she is recognized as a pioneer in the development of DNA sequencing for human rights investigations, and she is also a Senior Associate Core Member of the New York Genome Center.
THE COUNCIL: INTRODUCING THE W.H.O. SCIENCE COUNCIL THAT IS ABOUT TO CONTROL YOUR LIFE.
As we approach the final stages of the #WHO coup d'état attempt, it is time to expose the group of unelected people who will control your future and their alarming agenda!
#TheCouncil
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2/ In December 2023 the WHO produced a report that sets the stage to radical changes that soon will be enforced all the citizens of the world: make gene therapy (mRNA) key technology in the fight against infectious diseases, cancer, and combat any resistance to such technologies.
3/ It called to develop new gene therapy treatments against pathogens, promote investment in "equitable" development of the technology, use it as THE medical countermeasure mechanism to tackle pandemic threats, and to combat any resistance to the technology ("misinformation").
@robinmonotti 1) He uses the exaggerated Hamas dataset. 2) He uses a definition of children for anyone under 18 years old. 3) He say Palestinians were expelled in 1948, but don't mention many left because Arab nations told them to so they can butcher Jews in the war they started.
More below.
@robinmonotti 4) He compare the number of children who died to the sum total of children died 3 years before. He does not compare it to the number of children who died in other conflicts IN THE REGION, such as in Syria. That like comparing apples and pears.
More below.
@robinmonotti 5) The definition of who is a Palestinian by the UN is ANYONE WHO LIVED IN THE MANDATED PALESTINE FOR TWO YEARS prior to June 1848! No ancestors required!
This also made Egyptians who escaped Egypt not to become work slave in the creation of the Suez canal into Palestinians.