@R_H_Ebright comment sums it up nicely

The new viruses--named BANAL-20-52, BANAL-20-103, BANAL 20-236, BANAL 20-116, and BANAL 20-147--all are *less similar* than RaTG13 to SARS-CoV-02.

BANAL indeed.
But maybe not so BANAL after all...

From supplementary files

assets.researchsquare.com/files/rs-87196…
quite a long way from Wuhan though, even further than Mojiang ;)
Limestone Karsts of SE Asia
researchgate.net/publication/21…
DISTRIBUTION AND CHARACTER OF KARST IN THE LAO PDR.

researchgate.net/publication/23…
Can someone break the news to Eddie Holmes gently?

"None of these bat viruses harbors a furin cleavage site in the spike"

"Identification of strains of animal origin with a furin cleavage site may require additional sampling"

researchsquare.com/article/rs-871…
More on Furin Cleavage Site

However, we found no furin site in any of these viruses. Lack of furin cleavage may be explained by by acquisition of the furin cleavage site through passages of the virus in an alternate host"
"Finally, where these intergenomic recombinations arose and the epidemiological link with the first human cases remains to be established"
US DoD and Pasteur Institute were there in Feuang District where the closest bat coronavirus, Banal 20 52, came from, back in 2017, bat sampling....where they sampled several Rhinolophus Malayanus...
pasteur.la/project-carrie…
Bat "contacts" tested in Vientiane Province in 2020

thelancet.com/pdfs/journals/…
Laos is the flavour of the day it seems...
PREDICT 2016

All cov sequences generated from frugivorous bats (family Pteropodidae) clustered with other bat βCoVs of lineage D, whereas one coronavirus from Pipistrellus coromandra fell in the lineage C of βCoVs which also includes the MERS-CoV.

sciencedirect.com/science/articl…

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More from @BillyBostickson

16 Sep
Limited hangout by Callahan (allegedly an "Agency Man") who just happened to be in Nanjing on an "avian flu" project, when sars-cov-2 emerged in Wuhan. Close links to Robert Kadlec at BARDA/HHS, exposed by @hijodelcuervo and @_whitneywebb and @AlexisBadenMaye and my humble self.
2. Some very interesting comments in the article relevant to sars-cov-2 origins investigation which support claims in our third report regarding bat sampling activities by Wuhan Scientists.
researchgate.net/publication/35…
3. Dangers inherent in Field Sampling of Bats

"In many cases, infections attributed to biocontainment laboratory activities actually occurred outside the lab, often during field collection of viral samples" Image
Read 14 tweets
10 Sep
@ExpertisePoker @TheTexasPaladin Well no, i read it with an open mind and had some reservations about the timing claims, but at the same in light of the spike in care home deaths as well as the well known UK custom of murdering the elderly with opiods (Gosport case)

theguardian.com/society/2019/a…,
@ExpertisePoker @TheTexasPaladin Then considering the furore in France about the use of Rivotril in care homes, I felt it would be wrong to dismiss the claims
Family members of French nursing home residents to seek accountability for the deaths of 10s of 1000s of loved ones from Covid-19
france24.com/en/europe/2021…
@ExpertisePoker @TheTexasPaladin The French certainly took this issue seriously, see Alliance VITA:

Coronavirus: Rivotril® and Biomedical Ethics

alliancevita.org/en/2020/04/cor…

So not sure why you are dismissing it out of hand
Read 15 tweets
7 Sep
Intercepted the Jigsaw Puzzle
2. Wuhan University ABSL3
Experimental work using humanized mice will be conducted at the Center for Animal Experiment Biosafety 3 lab of Wuhan University at the School of Medicine in Wuhan, China.
3. Humanized mice for experimental infection

"To understand whether bat covs that utilize receptors found in people have potential to infect people, we will use Swiss albino mice (standard breed at Wuhan University) that have been genetically modified to have human receptors"
Read 19 tweets
4 Sep
Nicotine & SARS-CoV-2

COVID-19 may be a disease of the nicotinic cholinergic system

Nicotine is a cholinergic agonist & an important inhibitor of pro-inflammatory cytokines acting through the cholinergic anti-inflammatory pathway via α7-nAChRs.

ncbi.nlm.nih.gov/labs/pmc/artic…
Read 9 tweets
30 Aug
Poor Man's Covid-19 Emergency Kit (August 2021)

1. Replaced Ivermectin with Niclosamide (1000mg)
2. Added: Fenofibrate (145 mg/d )
3. Added: Fluvoxamine (150mg/d)
4. Replaced Ventolin Inhalers with Budesonide

March:


Original:
: Image
Considering adding Metformin as a prophylactic
1. Therapeutic Potential of Metformin in COVID-19: Reasoning for Its Protective Role sciencedirect.com/science/articl…
2. Metformin use reduces risk of death for patients with COVID-19 & diabetes
uab.edu/news/research/…

Any comments, Doctors?
3. Metformin frontiersin.org/articles/10.33…
4. Efficacy & Potential Mechanisms of Metformin in the Treatment of COVID-19 in the Diabetics: A Systematic Review
ncbi.nlm.nih.gov/labs/pmc/artic…
5. Diabetes mainstay metformin tamps down lung inflammation in COVID models
fiercebiotech.com/research/diabe…
Read 5 tweets

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