#COVID19 #NaturalImmunity #Infiammation
1/ Inflammation plays an essential role in the control of pathogens and in shaping the ensuing adaptive immune responses. ↘️↘️↘️
1/ Inflammation plays an essential role in the control of pathogens and in shaping the ensuing adaptive immune responses. ↘️↘️↘️
2/ Traditionally, innate immunity has been described as a rapid response triggered through generic and nonspecific means that by definition lacks the ability to remember. ↘️↘️↘️
3/ Recently, it has become clear that some innate immune cells are epigenetically reprogrammed or imprinted by past experiences. ↘️↘️↘️
4/ Remembrance of past pathogen encounters has classically been attributed to cohorts of antigen-specific memory T and B cells following the resolution of infection. ↘️↘️↘️
5/ This memory-conditioned inflammatory response, in conjunction with other secondary effector T cell functions, results in better control and more rapid resolution of both infection and the associated tissue pathology. ↘️↘️↘️
6/ Therefore, understanding of the impact of prior pathogen encounter on both innate and adaptive immunity is imperative for the design of innovative vaccination regimes. ↘️↘️↘️
7/ Please, refer to this article hindawi.com/journals/jir/2…
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