Not sure how anyone can read this @CIDRAP summary of the booster research and think that "booster" doses should be controversial. We risk wasting doses 1 & 2 if we don't give a 3rd. That additional dose is critical for continued protection.
Antibody levels from Pfizer vaccine with 3rd dose given 8-9 months after 2nd dose nejm.org/doi/full/10.10…
Decreasing antibody levels track with increased breakthrough infection. These data are pre-delta, so high antibody levels are likely to be far more important with delta, which spews 1000x-fold more virus. (not-yet-peer-reviewed preprint: medrxiv.org/content/10.110…)
I don't know why this is such a difficult concept: antibody protection is critical against pathogens that cause rapid and overwhelming infection. Cell-mediated immunity is slow. Simple explanation here: biodifferences.com/difference-bet…
• • •
Missing some Tweet in this thread? You can try to
force a refresh
Do people not read the methods sections of papers, in order to interpret whether the results are applicable to a given situation? I just don't get it. This is basic stuff.
I hope that the families of the vaccine hesitant who died figure out how badly they have been misled, and sues @VPrasadMDMPH and @UCSFMedicine for wrongful death.
The young man did not get vaccinated as a result of exaggeration the dangers of vaccine-induced myocarditis, when clearly the disease is more dangerous. Prasad and his GBD colleagues, and by extension UCSF, are party to this
Liver toxicity is a significant concern, particularly among people who are acutely ill and not eating. If the liver is depleted of a detoxifying substance called glutathione, toxic metabolites can add up. ncbi.nlm.nih.gov/pmc/articles/P…
Also, it can cause rebound headaches. I figured this out in my early 20s on my own. I never take more than 325mg at a time. Other pain relievers have the same problem of triggering headaches if taken often.
In case you are wondering about the ACIP (the people who decide on national immunization recommendations):
11 of the 15 members were appointed by Alex Azar, Trump’s Secretary of the U.S. Department of Health and Human Services. cdc.gov/vaccines/acip/…
4 of them were appointed during Trump’s last month in office, at a time when the maniacs at the Great Barrington Declaration were determining White House policy.
So if you are wondering why we aren’t getting boosters, this is likely part of the problem.
Now he is suing her for releasing tax documents that were legally hers, part of discovery from when she sued him for defrauding her out of her inheritance. washingtonpost.com/politics/2021/…
If you haven’t read Mary’s book (you should), you can get a gist of the awfulness of her uncle from this article. nytimes.com/2016/01/03/us/…